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无机阴离子对低温拜耳法中脱硅产物析出的影响
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作者 刘吉龙 潘晓林 +2 位作者 吴鸿飞 侯宪林 于海燕 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2024年第4期1300-1310,共11页
利用XRD、FT-IR、SEM和PSD等手段系统研究无机阴离子对低温拜耳法过程中脱硅产物(DSPs)的组成、结构以及微观形貌的影响。当溶液中存在氯化物、硫酸盐和碳酸盐时,形成氯化物型方钠石、碳酸盐型方钠石和黝方石,部分铝酸盐离子被阴离子杂... 利用XRD、FT-IR、SEM和PSD等手段系统研究无机阴离子对低温拜耳法过程中脱硅产物(DSPs)的组成、结构以及微观形貌的影响。当溶液中存在氯化物、硫酸盐和碳酸盐时,形成氯化物型方钠石、碳酸盐型方钠石和黝方石,部分铝酸盐离子被阴离子杂质取代。硫酸盐与DSPs的结合能力强于铝酸盐、氯化物和碳酸盐。随着阴离子浓度的增加,DSPs的粒径增大,且DSPs的团聚程度和圆形片层结构的厚度均有所增加。此外,阴离子杂质会促进沸石骨架的溶解和方钠石中四元环的形成,从而促进沸石向方钠石转化。 展开更多
关键词 拜耳法 水合铝硅酸钠 无机阴离子 脱硅 晶体结构
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Effect of Ce on microstructure and mechanical properties of Mg-Zn-Ce magnesium alloys
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作者 hong-fei wu Wen-xin Hu +4 位作者 Shao-bo Ma Zheng-hua Yang Wei Wang Feng Liu Wei He 《China Foundry》 SCIE CAS CSCD 2023年第4期271-279,共9页
The Mg-6Zn alloy with different contents of Ce was prepared by the gravity casting method,and then the Mg-6Zn-xCe(x=0,0.5,1.0,1.5,wt.%)alloys were extruded at 300℃and 350℃ after solution treatment.The phase constitu... The Mg-6Zn alloy with different contents of Ce was prepared by the gravity casting method,and then the Mg-6Zn-xCe(x=0,0.5,1.0,1.5,wt.%)alloys were extruded at 300℃and 350℃ after solution treatment.The phase constitution and microstructure evolution of Mg-Zn-xCe alloys were analyzed by X-ray diffraction(XRD),scanning electron microscopy(SEM),energy dispersive spectroscopy(EDS)and electron backscattering diffraction(EBSD).Meanwhile,the mechanical properties of the alloy were tested at room temperature.For as-cast alloys,the results show that the main compound in Mg-6Zn alloy is Mg4Zn7 phase,and the main compound is T-(MgZn)12Ce phase after the addition of different amounts of Ce.The microstructure and distribution of second phases are greatly improved after extrusion at 300℃and 350℃.Compared with initial mechanical properties,the strength and elongation increase obviously by means of extrusion at different temperatures.In addition,the microstructure after extrusion at 350℃is further analyzed according to EBSD data.The results show that rare earth element Ce probably promotes the activation of non-basal slip during the deformation process with the increase of Ce,which reduces the strength of basal texture and thus improves the plasticity of the alloy.Meanwhile,the increase of grain boundary migration ability leads to the gradual increase of recrystallization grain size and decreases the strength. 展开更多
关键词 Mg-Zn-Ce EXTRUSION MICROSTRUCTURE mechanical properties magnesium alloys
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Comparing the mechanism of four classic Gualou-Xiebai prescriptions for cardiovascular diseases with phlegm and blood stasis syndrome based on molecular network modeling
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作者 Bo Zhang Hua Zhong +2 位作者 Jia-Wei Chen Ya-Rong Liu hong-fei wu 《TMR Pharmacology Research》 2023年第3期33-45,共13页
Background:Four classical Traditional Chinese Medicine prescriptions,namely Gualou Xiebai Baijiu decoction,Gualou Xiebai Banxia decoction(GLXBBX),Zhishi Xiebai Guizhi decoction(ZSXBGZ)and Danlou prescription(DL),have ... Background:Four classical Traditional Chinese Medicine prescriptions,namely Gualou Xiebai Baijiu decoction,Gualou Xiebai Banxia decoction(GLXBBX),Zhishi Xiebai Guizhi decoction(ZSXBGZ)and Danlou prescription(DL),have been frequently used for treatment of phlegm and blood stasis syndrome(PBSS)-related cardiovascular diseases.However,its therapeutic mechanism has not been clearly elucidated.This study aimed to explore PBSS and its molecular mechanism,clarify and compare the mechanisms of four prescriptions in treating PBSS-related diseases.Method:In this study,we collected four prescriptions’compounds,predicted therapeutic targets,and enriched pathways which were based on network pharmacology.Then,we analysed the commen and different mechanisms by combing the network of components,targets and pathways.Finally,molecular docking was engaged to assess the binding potential of key compounds and hub targets.Results:We showed that four prescriptions’intersection genes(VEGFA,SRC,EGFR,etc.)were commonly enriched in PI3K-AKT signaling pathway,HIF-1 signaling pathway,etc.In addition,platelet activation and cAMP signaling pathway were singly enriched from the GLXBBX through unique compounds 12,13-epoxy-9-hydroxynonadeca-7,10-dienoic acid and Cyclo(L-tyrosyl-L-phenylalanyl).These bioactive compounds may exert GLXBBX’s unique pharmacological pathways via involving in mediating PPARA,PTGER3,etc.Sphingolipid signaling pathway was singly enriched from the ZSXBGZ through unique compounds tetramethoxyluteolin,ergosterol peroxide,etc.These bioactive compounds could mediate ADORA1,ADORA3 and TNFRSF1A to regulate ZSXBGZ’s unique pharmacological pathways.AMPK signaling pathway was singly enriched from the DL through unique compounds kaempferol,evofolinb,ethyl acid and aureusidin.These bioactive compounds were involved in mediating the main targets of AMPK signaling pathway,such as TNF,TNFRSF1A,etc.Conclusions:Our research demonstrated that GLXB-prescriptions involved in almost all pathological stages of PBSS-related cardiovascular diseases by modulating high-frequency shared pathways and targets mainly through key compounds(quercetin,mandenol,sitosteryl acetate and luteolin,etc.),for example,participate in the process of atherosclerosis,lipid metabolism,inflammation,immune response,thrombosis,inhibit inflammatory factors and platelet aggregation,regulate immune function,vascular function,oxidative stress.In addition to common pharmacological efficacies,there could also be specificities among GLXB prescriptions due to different compounds.For example,GLXBBX tends to regulate the function of vascular and endothelial barrier,prevent thrombosis.ZSXBGZ tends to regulate lipid metabolism and protect the heart from lipid accumulation.DL tends to maintain energy homeostasis and improve inflammation. 展开更多
关键词 Gualou Xiebai Baijiu decoction Gualou Xiebai Banxia decoction Zhishi Xiebai Guizhi decoction Danlou prescription phlegm and blood stasis syndrome network pharmacology analysis molecular docking
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低品位高硫铝土矿焙烧矿的溶出机理及晶体模拟 被引量:9
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作者 吴鸿飞 陈朝轶 +4 位作者 李军旗 兰苑培 王林珠 权变利 金会心 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2020年第6期1662-1673,共12页
采用悬浮焙烧与马弗炉焙烧对低品位高硫铝土矿进行预处理脱除硫和提高溶出性能。结果表明:悬浮焙烧能够有效除硫并显著提高铝土矿溶出性能,最佳溶出条件为:t=70 min,T=280℃,w(CaO)=8%,Nk=245 g/L,悬浮焙烧和马弗炉焙烧后氧化铝溶出率... 采用悬浮焙烧与马弗炉焙烧对低品位高硫铝土矿进行预处理脱除硫和提高溶出性能。结果表明:悬浮焙烧能够有效除硫并显著提高铝土矿溶出性能,最佳溶出条件为:t=70 min,T=280℃,w(CaO)=8%,Nk=245 g/L,悬浮焙烧和马弗炉焙烧后氧化铝溶出率分别为94.45%和92.08%,表观活化能分别为63.26和64.24k J/mol;基于悬浮焙烧和马弗炉焙烧铝土矿的XRD谱,通过MaterialsStudio建立两种Al2O3晶体模型。DFT模拟结果表明:相比于马弗炉焙烧,悬浮焙烧后矿物中Al-O更有利于氧化铝溶出,氧化铝晶体(104)和(113)晶面更易与NaOH结合。 展开更多
关键词 高硫铝土矿 悬浮焙烧 反应动力学 溶出机理 晶体结构 计算机模拟
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Relationship between XRCC1 polymorphisms and susceptibility to prostate cancer in men from Han, Southern China 被引量:5
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作者 Zheng Xu Li-Xin Hua +4 位作者 Li-Xin Qian Jie Yang Xin-Ru Wang Wei Zhang hong-fei wu 《Asian Journal of Andrology》 SCIE CAS CSCD 2007年第3期331-338,共8页
Aim: To investigate the association among XRCC1 polymorphisms, smoking, drinking and the risk of prostate cancer (PCa) in men from Han, Southern China. Methods: In a case-control study of 207 patients with PCa and... Aim: To investigate the association among XRCC1 polymorphisms, smoking, drinking and the risk of prostate cancer (PCa) in men from Han, Southern China. Methods: In a case-control study of 207 patients with PCa and 235 cancerfree controls, frequency-matched by age, we genotyped three XRCC1 polymorphisms (codons 194, 280 and 399) using the polymerase chain reaction-restriction fragment length polymorphism (PCR-RELP) method. Results: Among the three polymorphisms, we found that the XRCC1 Arg399Gln variant allele was associated with increased PCa risk (adjusted odd ratio [OR]: 1.67, 95% confident interval [CI]: 1.11-2.51), but the XRCC1 Arg 194Trp variant allele had a 38% reduction in risk of PCa (adjusted OR: 0.62, 95% CI: 0.41-0.93). However, there was no significant risk of PCa associated with Arg280His polymorphism. When we evaluated the three polymorphisms together, we found that the individuals with 194Arg/Arg wild-type genotype, Arg280His and Arg399Gln variant genotypes had a significantly higher risk of PCa (adjusted OR: 4.31; 95% CI: 1.24-14.99) than those with three wild-type genotypes. In addition, we found that Arg399Gln variant genotypes had a significant risk of PCa among heavy smokers (adjusted OR: 2.04; 95% CI: 1.03-4.05). Conclusion: These results suggest that polymorphisms of XRCC1 appear to influence the risk of PCa and may modify risks attributable to environmental exposure. 展开更多
关键词 XRCC1 polymorphism prostate cancer genetic susceptibility molecular epidemiology
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Suspension calcination and alkali leaching of low-grade high-sulfur bauxite:Desulfurization, mineralogical evolution and desilication 被引量:4
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作者 hong-fei wu Jun-qi Li +2 位作者 Chao-yi Chen Fei-long Xia Zhen-shan Xie 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 2020年第5期602-610,共9页
To enable the utilization of low-grade and high-sulfur bauxite, the suspension calcination was used to remove the sulfur and the activate silica minerals, and the calcinated bauxite was subjected to a desilication pro... To enable the utilization of low-grade and high-sulfur bauxite, the suspension calcination was used to remove the sulfur and the activate silica minerals, and the calcinated bauxite was subjected to a desilication process in Na OH solution under atmospheric pressure. The desulfurization and desilication properties and mineralogical evolution were studied by X-ray diffraction, thermogravimetry–differential thermal analysis, scanning electron microscopy, and FactSage methods. The results demonstrate that the suspension calcination method is efficient for sulfur removal: 84.21% of S was removed after calcination at 1000°C for 2 min. During the calcination process, diaspore and pyrite were transferred to α-Al2O3, magnetite, and hematite. The phase transformation of pyrite follows the order FeS2 → Fe3O4 → Fe2O3, and the iron oxides and silica were converted into iron silicate. In the alkali-soluble desilication process, the optimum condition was an alkali solution concentration of 110 g/L, a reaction time of 20 min, and a reaction temperature of 95°C. The corresponding desilication ratio and alumina loss ratio were 44.9% and 2.4%, respectively, and the alumina-to-silica mass ratio of the concentrate was 7.9. The Al2O3·2SiO2, SiO2, and Al2O3 formed during the calcination process could react with Na OH solution, and their activity decreased in the order of Al2O3·2 SiO2, SiO2, and Al2O3. 展开更多
关键词 LOW-GRADE BAUXITE sulfur SUSPENSION CALCINATION ALKALI-SOLUBLE DESILICATION Bayer process
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VEGF、VEGF-C和VEGFR-3蛋白表达增加与前列腺癌进展期的相关性研究(英文) 被引量:4
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作者 Jie Yang hong-fei wu +7 位作者 Li-Xin Qian Wei Zhang Li-Xin Hua Mei-Lin Yu Zhen Wang Zheng-Quan Xu Yuan-Geng Sui Xin-Ru Wang 《Asian Journal of Andrology》 SCIE CAS CSCD 2006年第2期169-175,共7页
目的:研究前列腺癌(PCa)组织及癌周正常组织中微血管密度(MVD)、血管内皮细胞生长因子(VEGF)、VEGF-C 及血管内皮细胞生长因子受体3(VEGFR-3)的表达差异,探讨 VEGF,VEGF-C 及 VEGFR-3蛋白的表达与 PCa 进展期的相关性。方法:采用 SABc ... 目的:研究前列腺癌(PCa)组织及癌周正常组织中微血管密度(MVD)、血管内皮细胞生长因子(VEGF)、VEGF-C 及血管内皮细胞生长因子受体3(VEGFR-3)的表达差异,探讨 VEGF,VEGF-C 及 VEGFR-3蛋白的表达与 PCa 进展期的相关性。方法:采用 SABc 免疫组化染色法检测71例 PCa 患者的组织样本中 CD34、VEGF、VEGF-C 及 VEGFR-3的表达。结果:与癌周正常组织相比,PCa 上皮/肿瘤细胞内 VEGF、VEGF-C 及 VEGFR-3的表达均显著上调(P<0.01)。Jewett-Whitmore 分期的 D 期患者癌灶内 VEGF-C 和 VEGFR-3的表达均显著高于 A、B 或 C 期患者(P<0.01)。另外在 Jewett-Whitmore 分期与 VEGF-C 表达(r_s=0.738,P<0.01)、临床分期与 VEGFR-3(r_s=0.410,P<0.01)、VEGF-C 与 Gleason 评分(r_s=0.401,P<0.01)、VEGFR-3与 Gleason评分(r_s=0.581,P<0.001)、MVD 与 VEGF(r_s=0.492,P<0.001)之间均存在显著相关性。结论:VEGF、VEGF-C 和 VEGFR-3的表达增加与 PCa 的进展期密切相关。VEGF 促进肿瘤组织内部微血管密度增加,从而维持肿瘤组织的生长优势:而 VEGF-C 及 VEGFR-3的主要作用在于促进肿瘤组织淋巴管形成,进而促进癌细胞的转移。 展开更多
关键词 血管内皮生长因子 基因表达 前列腺癌 肿瘤级数
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The ejaculatory duct ectopically invading the bladder with multiple congenital malformations of the homolateral urogenital system: a report of a rare case and an embryological review 被引量:2
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作者 Feng Wang hong-fei wu Jie Yang 《Asian Journal of Andrology》 SCIE CAS CSCD 2009年第3期379-384,共6页
We report a rare case of a left ejaculatory duct that allotropically protrudes towards or invades the left vesicle triangular area with its dead end. The patient simultaneously exhibited multiple congenital malformati... We report a rare case of a left ejaculatory duct that allotropically protrudes towards or invades the left vesicle triangular area with its dead end. The patient simultaneously exhibited multiple congenital malformations of the homolateral urogenital system, such as absence of the left kidney, dysplasia and allotopia of the left seminal vesicle, absence of the left ureterostoma, separation between the left testis and the epididymis tail, and maldevelopment of the left testis. According to all clinical and laboratory evidence, the case represented a new syndrome, which we named Wuyang's syndrome. It involved a rare phenomenon in embryonic development; the dysplastic proximal vas precursor, having intruded into a common mesonephric duct and accidentally encroaching on the ureteric bud position, resulted in the absence or dysplasia of the homolateral urinary tract and ectopic invasion of the bladder by the homolateral seminal tract. 展开更多
关键词 common mesonephric duct proximal vas precursor ureteric bud urogenital system
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Pressure assessment in intercavernous embedding of bulboperineal urethra for treatment of urinary incontinence after prostatic operation
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作者 Li-Xin QIAN hong-fei wu +4 位作者 Yuan-Geng SHUI Wei ZHANG Shuang-Guan CHENG Min GU Zheng-Quan XU Department of Urology, First Affiliated Hospital,Nanjing Medical University, Nanjing 210029, China 《Asian Journal of Andrology》 SCIE CAS CSCD 2001年第3期235-237,共3页
Aim: To put forward criteria for the pressure assessment in the operation of intercavernous embedding of bulboper-ineal urethra for the treatment of urinary incontinence after prostatic operation. Methods: A F14 ureth... Aim: To put forward criteria for the pressure assessment in the operation of intercavernous embedding of bulboper-ineal urethra for the treatment of urinary incontinence after prostatic operation. Methods: A F14 urethral catheter isinserted during the operation and upon suturing the corpora cavernosa centrally, the catheter is slowly pushed in andpulled out in order that the operator feels a certain degree of close-fit resistance. The degree of tightness of the stitches,which regulate the compression pressure, is adjusted in accordance with this close-fit sensation. To further ascertain theadequacy of the force of compression, the bladder is filled with 300 ml physiological saline and observe the appropriate-ness (size and continuity) of the outflow stream when the lower abdomen is depressed with a pressure of 80 - 90 cmH_2O. The operation was given to six patients suffered from urinary incontinence for 20 or more months after prostaticoperation. Results: Five cases achieved complete recovery, while the therapeutic effect of the 6th one was not sat-isfactory . A second stage operation was carried out 3 months later with the addition of one more stitch both proximallyand distally to reinforce the compression force. The condition was improved dramatically. The follow-up period aver-aged 3.5 years. Conclusion; The adequacy of the compression pressure exerted by the juxtaposed corpora cavernosais the key point determining the outcome of the operation. The measures for assessing the compression pressure suggest-ed by the authors are helpful in obtaining the good results of the present paper (6/6 success) as compared with 25/34success in the previous report. (Asian J Androl 2001 Sep; 3: 235 — 237) 展开更多
关键词 prostatic operation urinary incontinence intercavemous embeding pressure assessment
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Antibody and complement levels in patients with hypersplenism associated with cirrhotic portal hypertension and therapeutic principles
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作者 Kun Zhang Min Zeng +5 位作者 Ye-Juan Li hong-fei wu Jin-Cai wu Zhen-Sheng Zhang Jin-Fang Zheng Yun-Fu Lv 《World Journal of Clinical Cases》 SCIE 2022年第36期13208-13215,共8页
BACKGROUND Hypersplenism associated with cirrhotic portal hypertension is a common condition often resulting from hepatitis B-related cirrhosis.However,the levels of immunoglobulin(Ig)and complement in patients with h... BACKGROUND Hypersplenism associated with cirrhotic portal hypertension is a common condition often resulting from hepatitis B-related cirrhosis.However,the levels of immunoglobulin(Ig)and complement in patients with hypersplenism associated with cirrhotic portal hypertension remain unclear.This study was undertaken to determine the levels of Ig and complement in these patients,the relationship between these levels and Child-Pugh class and their clinical significance.AIM To investigate the antibody(Ig)and complement levels in patients with hypersplenism associated with cirrhotic portal hypertension and their clinical significance.METHODS Clinical data of 119 patients with hypersplenism associated with cirrhotic portal hypertension were statistically analyzed and compared with those of 128 control patients.RESULTS IgA and IgG levels in patients with hypersplenism were significantly higher than controls(P<0.001).There was no significant difference in IgM between the two groups(P=0.109).C3 and C4 levels in patients with hypersplenism were significantly lower than controls(P<0.001).As liver function decreased,IgA and IgG levels increased(P<0.001),and C3 and C4 levels decreased(P<0.001).CONCLUSION Patients with hypersplenism associated with cirrhotic portal hypertension have significantly higher antibody(IgA and IgG)levels and significantly lower complement(C3 and C4)levels,which are both related to liver damage.Clinically,the administration of anti-hepatitis virus agents and protection of liver function should be strengthened. 展开更多
关键词 Hypersplenism associated with cirrhotic portal hypertension COMPLEMENT Treatment HEPATITIS B-immunoglobulin
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A 30-year retrospective study of rare ectopic seminal tract opening cases 被引量:2
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作者 hong-fei wu Jia-Geng Zhu +4 位作者 Jian-Zhong Lin Guang-Dong Shi Jia-Qi Yu Wei-Zhang Xu Hong-Bo Yu 《Asian Journal of Andrology》 SCIE CAS CSCD 2020年第3期287-291,共5页
Ectopic seminal tract openi ng is a rare con genital malformation.Until rece ntly,there has been a lack of comprehensive reporting on the condition.The purpose of this retrospective study is to summarize the experienc... Ectopic seminal tract openi ng is a rare con genital malformation.Until rece ntly,there has been a lack of comprehensive reporting on the condition.The purpose of this retrospective study is to summarize the experience of diagnosis and treatment of this condition based on 28 clinical practice cases throughout the past 30 years.We conducted auxiliary examinations on such patients including routine tests,imaging examinations,and endoscopy.Among these 28 cases,there were ectopic opening of vas deferens into enlarged prostatic utricles(6 cases);ejaculatory ducts into enlarged prostatic utricles,Mullerian ducts cysts,and urethras(18 cases,2 cases,and 1 case,respectively);and ectopic opening of the unilateral vas deferens and the contralateral ejaculatory duct into enlarged prostatic utricle(1 case).The size of the enlarged prostatic utricle,the type of ectopic seminal tract opening,and the opening's location effectively assisted in the selection of clinical treatment methods,including transurethral fenestration of the utricle,transurethral cold-knife incision,open operation,laparoscopic operation,and conservative treatment.Satisfactory effect was achieved during follow-up.In conclusion,a definite diagnosis and personalized treatment are especially important for patients with ectopic seminal tract opening. 展开更多
关键词 congenital malformation ectopic opening ejaculatory duct enlarged prostatic utricle vas deferens
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