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外耳道灌注派瑞松治疗真菌性外耳道炎的疗效分析 被引量:5
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作者 曾宇慧 胡志瑛 +2 位作者 林泓霖 蔡伟伟 黄郁林 《中国内镜杂志》 2022年第2期56-62,共7页
目的探讨外耳道灌注给药方式对真菌性外耳道炎的临床价值。方法选取单侧真菌性外耳道炎患者202例,随机分为传统涂布组(n=89)和外耳道灌注组(n=113)。所有患者均在耳内镜下清理外耳道真菌团,冲洗外耳道后给予派瑞松乳膏治疗1周,第10天复... 目的探讨外耳道灌注给药方式对真菌性外耳道炎的临床价值。方法选取单侧真菌性外耳道炎患者202例,随机分为传统涂布组(n=89)和外耳道灌注组(n=113)。所有患者均在耳内镜下清理外耳道真菌团,冲洗外耳道后给予派瑞松乳膏治疗1周,第10天复诊评估疗效,并随访6个月。结果真菌性外耳道炎发病率呈逐年上升的趋势,主要发病于夏季。202例患者主要临床表现为耳痒(90.6%)、耳堵塞感(85.1%)和耳漏(54.0%);危险因素主要是掏耳(98.0%),其次是配戴耳机/耳塞(37.6%)。真菌培养阳性率为84.4%(27/32),曲霉菌属占多数(74.1%)。1周疗程完成后,传统涂布组有效71例,无效18例,外耳道灌注组有效103例,无效10例,有效率分别为79.8%和91.2%,两组患者比较,差异有统计学意义(P<0.05)。随访6个月后,传统涂布组复发22例,外耳道灌注组复发9例,复发率分别为29.3%(22/75)和8.9%(9/101),两组患者比较,差异有统计学意义(P<0.05)。复发主要原因是工作环境潮湿和年龄较大。在治疗过程中,传统涂布组耳痛发生率高于外耳道灌注组。结论外耳道灌注派瑞松治疗真菌性外耳道炎,操作简便,效果明显,不易复发,便于临床特别是基层单位推广应用。 展开更多
关键词 真菌性外耳道炎 派瑞松 外耳道灌注 耳内镜 曲霉菌
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Advances in lithium niobate photonics:development status and perspectives 被引量:11
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作者 Guanyu Chen Nanxi Li +7 位作者 Jun Da Ng hong-lin lin Yanyan Zhou Yuan Hsing Fu Lennon Yao Ting Lee Yu Yu Ai-Qun Liu Aaron J.Danner 《Advanced Photonics》 SCIE EI CAS CSCD 2022年第3期40-82,共43页
Lithium niobate(LN)has experienced significant developments during past decades due to its versatile properties,especially its large electro-optic(EO)coefficient.For example,bulk LN-based modulators with high speeds a... Lithium niobate(LN)has experienced significant developments during past decades due to its versatile properties,especially its large electro-optic(EO)coefficient.For example,bulk LN-based modulators with high speeds and a superior linearity are widely used in typical fiber-optic communication systems.However,with everincreasing demands for signal transmission capacity,the high power and large size of bulk LN-based devices pose great challenges,especially when one of its counterparts,integrated silicon photonics,has experienced dramatic developments in recent decades.Not long ago,high-quality thin-film LN on insulator(LNOI)became commercially available,which has paved the way for integrated LN photonics and opened a hot research area of LN photonics devices.LNOI allows a large refractive index contrast,thus light can be confined within a more compact structure.Together with other properties of LN,such as nonlinear/acousto-optic/pyroelectric effects,various kinds of high-performance integrated LN devices can be demonstrated.A comprehensive summary of advances in LN photonics is provided.As LN photonics has experienced several decades of development,our review includes some of the typical bulk LN devices as well as recently developed thin film LN devices.In this way,readers may be inspired by a complete picture of the evolution of this technology.We first introduce the basic material properties of LN and several key processing technologies for fabricating photonics devices.After that,various kinds of functional devices based on different effects are summarized.Finally,we give a short summary and perspective of LN photonics.We hope this review can give readers more insight into recent advances in LN photonics and contribute to the further development of LN related research. 展开更多
关键词 lithium niobate ETCHING PHOTONICS integrated optics NANOTECHNOLOGY devices.
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