Relationship between different surgical methods,hemorrhage position,hemorrhage volume,surgical timing,and treatment outcome of hypertensive intracerebral hemorrhage

BACKGROUND:The present study aimed to explore the relationship between surgical methods,hemorrhage position,hemorrhage volume,surgical timing and treatment outcome of hypertensive intracerebral hemorrhage(HICH).METHODS:A total of 1 310 patients,who had been admitted to six hospitals from January 2004 to January 2008,were divided into six groups according to different surgical methods:craniotomy through bone fl ap(group A),craniotomy through a small bone window(group B),stereotactic drilling drainage(group C1 and group C2),neuron-endoscopy operation(group D) and external ventricular drainage(group E) in consideration of hemorrhage position,hemorrhage volume and clinical practice. A retrospective analysis was made of surgical timing and curative effect of the surgical methods.RESULTS:The effectiveness rate of the methods was 74.12% for 1 310 patients after onemonth follow-up. In this series,the disability rate was 44.82% 3–6 months after the operation. Among the 1 310 patients,241(18.40%) patients died after the operation. If hematoma volume was >80 mL and the operation was performed within 3 hours,the mortality rate of group A was signifi cantly lower than that of groups B,C,D,and E(P<0.05). If hematoma volume was 50–80 mL and the operation was performed within 6–12 hours,the mortality rate of groups B and D was lower than that of groups A,C and E(P<0.05). If hematoma volume was 20–50 mL and the operation was performed within 6–24 hours,the mortality rate of group C was lower than that of groups A,B and D(P<0.05).CONCLUSIONS:Craniotomy through a bone f lap is suitable for patients with a large hematoma and hernia of the brain. Stereotactic drilling drainage is suggested for patients with hematoma volume less than 80 mL. The curative effect of HICH individualized treatment would be improved via the suitable selection of operation time and surgical method according to the position and volume of hemorrhage.

Effects of fumigation and washing with Shujin Huoluo decoction combined with Duhuo Parasitic decoction on TIMP-1 and PON1 levels in KOA patients

Objective:To study the effect of fumigation and washing with Shujin Huoluo Decoction combined with Duhuo Parasitic Decoction on Metalloproteinase inhibitor-1(TIMP-1)and Oxyphosphatase 1,PON1)level.Methods:A total of 100 KOA patients,59 males and 41 females,were selected for diagnosis and treatment in our hospital from November 2018 to November 2019.The patients were divided into the control group and the combined group with 50 patients each according to a completely random method.The control group was treated with Duhuo Parasitic Decoction and the combined group was treated with Duhuo Parasitic Decoction and Shujinhuoluo decoction.Detection of TIMP-1,PON1,Matrix metalloproteinase-3(MMP-3),C-reactive protease(CRP),Tumor necrosis factor-alpha(TNF-α)and Superoxide dismutase(SOD)levels.WOMAC score,Lysholm score,and VAS score were evaluated.Results:The levels of TIMP-1 and PON1 in the combined group were higher than those in the control group after treatment,and the levels of MMP-3 were lower than those in control group(P<0.05).The WOMAC score and VAS score of the combined group were lower than those of the control group,and the Lysholm score was higher than that of control group(P<0.05).The levels of CRP and TNF-αin the combined group were lower than those in the control group,and the SOD levels were higher than those in control group(P<0.05).The total effective rate of the combined group was higher than the total effective rate of control group(P<0.05).Conclusion:The combination of fumigation and washing with Shujin Huoluo Decoction and Duhuo Parasitic Decoction has a significant effect on the treatment of KOA patients.It improves the levels of TIMP-1 and PON1,improves the knee function of patients and pain.

Millennial climate changes since MIS 3 revealed by element records in deep-sea sediments from northern South China Sea

High resolution elemental records in core MD05-2903 from the northern South China Sea were obtained from XRF scanning and grain size and mineral component analyses.The K/Ti curve reveals climate changes since MIS 3 on a millennial scale,representing one of the best such records so far from deep-sea sediments of the South China Sea.When compared our K/Ti record with other climate records from high latitude ice cores and from East Asia stalagmites,variations in the K/Ti record show some typical saw-shaped features of rapid climate changes in the Northern Hemisphere.Grain size analysis reveals a close relationship between variations in K/Ti and in the fine end-member grain size.XRD analysis confirms that high K/Ti layers were dominated by K-rich weathering minerals,especially illite,while low K/Ti layers contain low illite but high abundance of Ti-rich heavy minerals.Therefore,the K/Ti record reflects changes in the input and deposition of fine weathering minerals and heavy minerals in the northern South China Sea region during stadials and interstadials.These elemental changes were largely controlled by variations in rainfall,erosion,and fluvial transportation induced by East Asia Monsoon.

Surface reconstruction from unorganized point clouds based on edge growing

Owing to unorganized point cloud data,unexpected triangles,such as holes and slits,may be generated during mesh surface reconstruction.To solve this problem,a mesh surface reconstruction method based on edge growing from unorganized point clouds is proposed.The method first constructs an octree structure for unorganized point cloud data,and determines the k-nearest neighbor for each point.Subsequently,the method searches for flat areas in the point clouds to be used as the initial mesh edge growth regions,to avoid incorrect reconstruction of the mesh surface owing to the growth of initial sharp areas.Finally,the optimal mesh surface is obtained by controlling the mesh edge growing based on compulsive restriction and comprehensive optimization criteria.The experimental results of mesh surface reconstruction show that the method is feasible and shows high reconstruction performance without introducing holes or slits in the reconstructed mesh surface.

A New Sign for Internal Carotid Artery Dissection Diagnosis by Ultrasound： An Unusual Curve of Bloodstream

To the Editor：Internal carotid artery dissection （ICAD） is one of the main causes of stroke in young-and middle-aged adults with a current mortality rate of 40%.Delayed diagnosis and treatment can result in permanent neurological impairment and/or death.[1] Currently,digital subtraction angiography （DSA） is considered the gold standard for diagnosis while conventional ultrasound （US） is utilized as a screening tool.The sonographic features of ICAD include a luminal flap,stenosis,or occlusion secondary to the presence ofhematoma and/or thrombus.These characteristics may be subtle,which diminishes US sensitivity for detecting ICAD.The following case report exemplifies US ability to diagnose ICAD through the demonstration of an unusual curve and the detection of an intraluminal hematoma.