期刊文献+
共找到11篇文章
< 1 >
每页显示 20 50 100
铜/钢爆炸焊接复合界面的显微组织及晶粒结构演化机理
1
作者 杨明 张冰原 +2 位作者 马宏昊 王金相 熊家艺 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2024年第5期1588-1605,共18页
采用光滑粒子仿真、先进表征和理论分析相结合的方法,对铜/钢复合材料爆炸焊接过程中的界面瞬态行为进行深入研究,并详细阐述其显微组织演化机制。根据仿真数据重构波形完整的演化过程,并揭示各种界面特征的形成机制。多尺度EBSD分析表... 采用光滑粒子仿真、先进表征和理论分析相结合的方法,对铜/钢复合材料爆炸焊接过程中的界面瞬态行为进行深入研究,并详细阐述其显微组织演化机制。根据仿真数据重构波形完整的演化过程,并揭示各种界面特征的形成机制。多尺度EBSD分析表明,界面附近区域呈多样性的晶粒结构,其演化机制主要受塑性流动、动态再结晶和凝固形核三个过程的控制。最后,通过纳米压痕实验建立晶粒结构与力学性能之间的关系。 展开更多
关键词 爆炸焊接 铜/钢复合材料 成波机理 晶粒结构 纳米压痕
下载PDF
Experimental research on the launching system of auxiliary charge with filter cartridge structure
2
作者 Zi-Jun Chen Ze He +2 位作者 hong-hao ma Lu-Qing Wang Zhao-Wu Shen 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第1期41-48,共8页
A launching system with a filter cartridge structure was proposed to improve the muzzle velocity of the projectile.The combustion chamber of the launching system is divided into two fixed chambers,one is located in th... A launching system with a filter cartridge structure was proposed to improve the muzzle velocity of the projectile.The combustion chamber of the launching system is divided into two fixed chambers,one is located in the breech chamber,and the other is arranged in the barrel.The breech chamber charge was ignited first,and the charges in the auxiliary chambers were ignited by the high-temperature,highpressure combustible gas trailing the projectile.In this way,the combustible gas in the auxiliary chambers could compensate for the pressure drop caused by the movement of the projectile.The proposed device features the advantage of launching a projectile with high muzzle velocity without exceeding the maximum pressure in the chamber.In order to obtain some internal ballistic characteristics of the launch system,some critical structure,such as the length of the filter cartridge auxiliary charge,the combustion degree of the propellant in the chamber,and the length of the barrel,are discussed.The experimental results show that with the increased auxiliary charge length,a pressure plateau or even a secondary peak pressure can be formed,which is less than the peak pressure.The projectile velocity increased by 23.57%,14.64%,and 7.65%when the diaphragm thickness was 0 mm,1 mm,and2 mm,respectively.The muzzle velocity of the projectile can be increased by 13.42%by increasing the length of the barrel.Under the same charge condition,with the increase of barrel length,the energy utilization rate of propellant increases by 28.64%. 展开更多
关键词 Interior ballistics Charge structures Launch system Charge design
下载PDF
Microstructure and mechanical properties of Al-Fe meshing bonding interfaces manufactured by explosive welding 被引量:12
3
作者 Ming YANG hong-hao ma +2 位作者 Zhao-wu SHEN Dai-guo CHEN Yong-xin DENG 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2019年第4期680-691,共12页
In order to improve the mechanical properties of Al.Fe transition joints manufactured by explosive welding,meshing bonding interfaces were obtained by prefabricating dovetail grooves in base plates.The microstructure ... In order to improve the mechanical properties of Al.Fe transition joints manufactured by explosive welding,meshing bonding interfaces were obtained by prefabricating dovetail grooves in base plates.The microstructure and mechanical properties of the meshing interfaces were systematically investigated.The microstructure observation showed that metallurgical bonding without pores was created in the form of direct bonding and melting zone bonding at the interface.Fractography on tensile specimens showed cleavage fracture on the steel side and ductile fracture on the aluminum side near the interfaces.The tensile shear test results indicated that the shear strength of the meshing interface 0°and 90°was increased by 11%and 14%,respectively,when being compared to that of the ordinary Al.Fe transition joints.The values of microhardness decreased as the distance from the interface increased.After three-point bending,cracks were observed at the bonding interface for some specimens due to the existence of brittle Fe.Al compounds. 展开更多
关键词 explosive welding meshing interface ALUMINUM stainless steel
下载PDF
Calculating detonation performance of explosives by VLWR thermodynamics code introduced with universal VINET equation of state
4
作者 Qin Liu Ying-liang Duan +3 位作者 Wei Cao hong-hao ma Xin-ping Long Yong Han 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2022年第6期1041-1051,共11页
Thermodynamic calculation is the theoretical basis for the study of initiation and detonation,as well as the prerequisite for forecasting the detonation performance of unknown explosives.Based on the VLWR(Virial-Wu)th... Thermodynamic calculation is the theoretical basis for the study of initiation and detonation,as well as the prerequisite for forecasting the detonation performance of unknown explosives.Based on the VLWR(Virial-Wu)thermodynamic code,this paper introduced the universal solid equation of state(EOS)VINET.In order to truly reflect the compressibility of nanocarbon under the extremely high-temperature and high-pressure environment in detonation,an SVM(support vector machine)was utilized to optimize the input parameters of carbon.The detonation performance of several explosives with different densities was calculated by the optimized universal EOS,and the results show that the thermodynamic code coupled with the universal solid EOS VINET can predict the detonation performance parameters of explosives well.To investigate the application of the thermodynamic code with the improved VINET EOS in the working capacity of explosives,the interrelationship between pressure P-particle velocity u and pressure P-volume V were computed for the detonation products of TNT and HMX-based PBX(HMX:binder:insensitive agent=95:4.3:0.7)in the CJ isentropic state.A universal curve proposed by Cooper was used to compared the computed isentropic state,where the ratio of pressure to CJ state were plotted against the ratio of velocity to CJ state.The parameters of the JWL(Jones-Wilkins-Lee)EOS for detonation products were obtained by fitting the P-V curve.The cylinder tests of TNT and HMX-based PBX were numerically simulated using the LS-DYNA,it is verified that,within a certain range,the improved algorithm has superiority in describing the working capacity of explosives. 展开更多
关键词 Detonation performance Thermodynamic calculation VINET equation of state VLWR thermodynamics Code Support vector machine Cylinder test
下载PDF
Deformation and Spallation of Explosive Welded Steels under Gas Gun Shock Loading 被引量:1
5
作者 Ying Yu Chao Li +2 位作者 hong-hao ma Mei-Lan Qi Sheng-Nian Luo 《Chinese Physics Letters》 SCIE CAS CSCD 2018年第1期104-108,共5页
We investigate deformation and spallation of explosive welded bi-steel plates under gas gun shock loading.Free surface histories are measured to obtain the Hugoniot elastic limit and spall strengths at different impac... We investigate deformation and spallation of explosive welded bi-steel plates under gas gun shock loading.Free surface histories are measured to obtain the Hugoniot elastic limit and spall strengths at different impact velocities.Pre-and post-shock microstructures are characterized with optical metallography,scanning electron microscopy,and electron backscatter diffraction.In addition,the Vickers hardness test is conducted.Explosive welding can result in a wavy steel/steel interface,an ultrafine grain region centered at the interface,and a neighboring high deformation region,accompanied by a hardness with the highest value at the interface.Additional shock compression induces a further increase in hardness,and shock-induced deformation occurs in the form of twinning and dislocation slip and depends on the local substructure.Spall damage nucleates and propagates along the ultrafine grain region,due to the initial cracks or weak interface bonding.Spall strengths of bimetal plates can be higher than its constituents.Plate impact offers a promising method for improving explosive welding. 展开更多
下载PDF
Effect of hydrogen-storage pressure on the detonation characteristics of emulsion explosives sensitized by glass microballoons 被引量:3
6
作者 Ji-ping Chen hong-hao ma +2 位作者 Yi-xin Wang Liang-liang Huang Zhao-wu Shen 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2022年第5期747-754,共8页
In this study,hydrogen-storage glass microballoons were introduced into emulsion explosives to improve the detonation performance of the explosives.The effect of hydrogen-storage pressure on the detonation characteris... In this study,hydrogen-storage glass microballoons were introduced into emulsion explosives to improve the detonation performance of the explosives.The effect of hydrogen-storage pressure on the detonation characteristics of emulsion explosives was systematically investigated.Detonation velocity experiments shows that the change of sensitizing gas and the increase of hydrogen pressure have different effects on the detonation velocity.The experimental parameters of underwater explosion increase first and then decreases with the increase of hydrogen pressure.The decrease of these parameters indicates that the strength of glass microballoons is the limiting factor to improve the detonation performance of hydrogen-storage emulsion explosives.Compared with the traditional emulsion explosives,the maximum peak pressure of shock wave of hydrogen-storage emulsion explosives increases by 10.6%at 1.0 m and 10.2%at 1.2 m,the maximum values of shock impulse increase by 5.7%at 1.0 m and 19.4%at 1.2 m.The stored hydrogen has dual effects of sensitizers and energetic additives,which can improve the energy output of emulsion explosives. 展开更多
关键词 Emulsion explosives Hydrogen-storage pressure Glass microballoons Underwater explosion
下载PDF
CEPC Technical Design Report 被引量:1
7
作者 Waleed Abdallah Tiago Carlos Adorno de Freitas +1111 位作者 Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed Xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An Rui An Daniele Paolo Anderle Stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai Yu Bai Yang Bai Vipul Bairathi Csaba Balazs Philip Bambade Yong Ban Tripamo Bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci Xiao-Jun Bi Yuanjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng Binglin Denis Bodrov Anton Bogomyagkov Serge Bondarenko Stewart Boogert maarten Boonekamp marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi Igor Boyko Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia Hua Cai Wenyong Cai Wujun Cai Yijian Cai Yizhou Cai Yuchen Cai Haiying Cai Huacheng Cai Lorenzo Calibbi Junsong Cang Guofu Cao Jianshe Cao Antoine Chance Xuejun Chang Yue Chang Zhe Chang Xinyuan Chang Wei Chao Auttakit Chatrabhuti Yimin Che Yuzhi Che Bin Chen Danping Chen Fuqing Chen Fusan Chen Gang Chen Guoming Chen Hua-Xing Chen Huirun Chen Jinhui Chen Ji-Yuan Chen Kai Chen mali Chen Mingjun Chen Mingshui Chen Ning Chen Shanhong Chen Shanzhen Chen Shao-Long Chen Shaomin Chen Shiqiang Chen Tianlu Chen Wei Chen Xiang Chen Xiaoyu Chen Xin Chen Xun Chen Xurong Chen Ye Chen Ying Chen Yukai Chen Zelin Chen Zilin Chen Gang Chen Boping Chen Chunhui Chen Hok Chuen Cheng Huajie Cheng Shan Cheng Tongguang Cheng Yunlong Chi Pietro Chimenti Wen Han Chiu Guk Cho Ming-Chung Chu Xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui Xiaohao Cui Zhaoyuan Cui Brunella D'Anzi Ling-Yun Dai Xinchen Dai Xuwen Dai Antonio De maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio Elisa Del Core Shuangxue Deng Wei-Tian Deng Zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding Siqin Dingl Yadong Ding Haiyi Dong Jianing Dong Jing Dong Lan Dong Mingyi Dong Xu Dong Yipei Dong Yubing Dong Milos Dordevic marco Drewes Mingxuan Du Mingxuan Du Qianqian Du Xiaokang Du Yanyan Du Yong Du Yunfei Du Chun-Gui Duan Zhe Duan Yahor Dydyshka Ulrik Egede Walaa Elmetenawee Yun Eo Ka Yan Fan Kuanjun Fan Yunyun Fan Bo Fang Shuangshi Fang Yuquan Fang Ada Farilla Riccardo Farinelli Muhammad Farooq Angeles Faus Golfe Almaz Fazliakhmetov Rujun Fei Bo Feng Chong Feng Junhua Feng Xu Feng Zhuoran Feng Zhuoran Feng Luis Roberto Flores Castillo Etienne Forest Andrew Fowlie Harald Fox Hai-Bing Fu Jinyu Fu Benjamin Fuks Yoshihiro Funakoshi Emidio Gabrielli Nan Gan Li Gang Jie Gao Meisen Gao Wenbin Gao Wenchun Gao Yu Gao Yuanning Gao Zhanxiang Gao Yanyan Gao Kun Ge Shao-Feng Ge Zhenwu Ge Li-Sheng Geng Qinglin Geng Chao-Qiang Geng Swagata Ghosh Antonio Gioiosa Leonid Gladilin Ti Gong Stefania Gori Quanbu Gou Sebastian Grinstein Chenxi Gu Gerardo Guillermo Joao Guimaraes da Costa Dizhou Guo Fangyi Guo Jiacheng Guo Jun Guo Lei Guo Lei Guo Xia Guo Xin-Heng Guo Xinyang Guo Yun Guo Yunqiang Guo Yuping Guo Zhi-Hui Guo Alejandro Gutierrez-Rodriguez Seungkyu Ha Noman Habib Jan Hajer Francois Hammer Chengcheng Han Huayong Han Jifeng Han Liang Han Liangliang Han Ruixiong Han Yang Han Yezi Han Yuanying Han Tao Han Jiankui Hao Xiqing Hao Xiqing Hao Chuanqi He Dayong He Dongbing He Guangyuan He Hong-Jian He Jibo He Jun He Longyan He Xiang He Xiao-Gang He Zhenqiang He Klaus Heinemann Sven Heinemeyer Yuekun Heng maria A.Hernandez-Ruiz Jiamin Hong Yuenkeung Hor George W.S.Hou Xiantao Hou Xiaonan Hou Zhilong Hou Suen Hou Caishi Hu Chen Hu Dake Hu Haiming Hu Jiagen Hu Jun Hu Kun Hu Shouyang Hu Yongcai Hu Yu Hu Zhen Hu Zhehao Hua Jianfei Hua Chao-Shang Huang Fa Peng Huang Guangshun Huang Jinshu Huang Ke Huang Liangsheng Huang Shuhui Huang Xingtao Huang Xu-Guang Huang Yanping Huang Yonggang Huang Yongsheng Huang Zimiao Huang Chen Huanyuan Changgi Hua Jiaqi Hui Lihua Huo Talab Hussain Kyuyeong Hwang Ara loannisian Munawar Iqbal Paul Jackson Shahriyar Jafarzade Haeun Jang Seoyun Jang Daheng Ji Qingping Ji Quan Ji Xiaolu Ji Jingguang Jia Jinsheng Jia Xuewei Jia Zihang Ja Cailian Jiang Han Ren Jiang Houbing Jiang Jun Jiang Xiaowei Jiang Xin Jiang Xuhui Jiang Yongcheng Jiang Zhongjian Jiang Cheng Jiang Ruiqi Jiao Dapeng Jin Shan Jin Song Jin Yi Jin Junji Jis Sunghoon Jung Goran Kacarevic Eric Kajfasz Lidia Kalinovskaya Aleksei Kampf Wen Kang Xian-Wei Kang Xiaolin Kang Biswajit Karmakar Zhiyong Ke Rijeesh Keloth Alamgir Khan Hamzeh Khanpour Khanchai Khosonthongkee KhanchaiKhosonthongkee Bobae Kim Dongwoon Kim Mi Ran Kim Minsuk Kim Sungwon Kim On Kim Michael Klasen Sanghyun Ko Ivan Koop Vitaliy Kornienko Bryan Kortman Gennady Kozlov Shiqing Kuang Mukesh Kumar Chia Ming Kuo Tsz Hong Kwok Fran cois Sylvain Ren Lagarde Pei-Zhu Lai Imad Laktineh Xiaofei Lan Zuxiu Lan Lia Lavezzi Justin Lee Junghyun Lee Sehwook Lee Ge Lei Roy Lemmon longxiang Leng Sze Ching Leung Hai Tao Li Bingzhi Li Bo Li Bo Li Changhong Li Chao Li Cheng Li Cheng Li Chunhua Li Cui Li Dazhang Li Dikai Li Fei Li Gang Li Gang Li Gang Li Gaosong Li Haibo Li Haifeng Li Hai-Jun Li Haotian Li Hengne Li Honglei Li Huijing Li Jialin Li Jingyi Li Jinmian Li Jun Li Leyi Li Liang Li Ling Li Mei Li Meng Li Minxian Li Pei-Rong Li Qiang Li Shaopeng Li Shenghe Li Shu Li Shuo Li Teng Li Tiange Li Tong Li Weichang Li Weidong Li Wenjun Li Xiaoling Li Xiaomei Li Xiaonan Li Xiaoping Li Xiaoting Li Xin Li Xinqiang Li Xuekang Li Yang Li Yanwei Li Yiming Li Ying Li Ying-Ying Li Yonggang Li Yonglin Li Yufeng Li Yuhui Li Zhan Li Zhao Li Zhiji Li Tong Li Lingfeng Li Fei Li Jing Liang Jinhan Liang Zhijun Liang Guangrui Liao Hean Liao Jiajun Liao Libo Liao Longzhou Liao Yi Liao Yipu Liao Ayut Limphirat AyutLimphirat Tao Lin Weiping Lin Yufu Lin Yugen Lin Beijiang Liu Bo Liu Danning Liu Dong Liu Fu-Hu Liu Hongbang Liu Huangcheng Liu Hui Liu Huiling Liu Jia Liu Jia Liu Jiaming Liu Jianbei Liu Jianyi Liu Jingdong Liu Jinhua Liu Kai Liu Kang Liu Kun Liu Mengyao Liu Peng Liu Pengcheng Liu Qibin Liu Shan Liu Shidong Liu Shuang Liu Shubin Liu Tao Liu Tao Liu Tong Liu Wei Liu Xiang Liu Xiao-Hai Liu Xiaohui Liu Xiaoyu Liu Xin Liu Xinglin Liu Xingquan Liu Yang Liu Yanlin Liu Yao-Bei Liu Yi Liu Yiming Liu Yong Liu Yonglu Liu Yu Liu Yubin Liu Yudong Liu Yulong Liu Zhaofeng Liu Zhen Liu Zhenchao Liu Zhi Liu Zhi-Feng Liu Zhiqing Liu Zhongfu Liu Zuowei Liu Mia Liu Zhen Liu Xiaoyang Liu Xinchou Lou Cai-Dian Lu Jun-Xu Lu Qiu Zhen Lu Shang Lu Shang Lu Wenxi Lu Xiaohan Lu Yunpeng Lu Zhiyong Lu Xianguo Lu Wei Lu Bayarto Lubsandorzhiev Sultim Lubsandorzhiev Arslan Lukanov Jinliang Luo Tao Luo xiaoan Luo Xiaofeng Luo Xiaolan Luo Jindong Lv Feng Lyu Xiao-Rui Lyu Kun-Feng Lyu Ande ma hong-hao ma Jun-Li ma Kai ma Lishuang ma Na ma Renjie ma Weihu ma Xinpeng ma Yanling ma Yan-Qing ma Yongsheng ma Zhonghui ma Zhongjian ma Yang ma Mousam maity Lining mao Yanmin mao Yaxian mao Aure lien martens Caccia massimo Luigi maria Shigeki matsumoto Bruce Mellado Davide Meloni Lingling Men Cai Meng Lingxin Meng Zhenghui Mi Yuhui Miao mauro Migliorati Lei Ming Vasiliki A.Mitsou Laura Monaco Arthur Moraes Karabo Mosala Ahmad Moursy Lichao Mu Zhihui Mu Nickolai Muchnoi Daniel Muenstermann DanielMuenstermann Pankaj Munbodh William John Murray Jerome Nanni Dmitry Nanzanov Changshan Nie Sergei Nikitin Feipeng Ning Guozhu Ning Jia-Shu Niu Juan-Juan Niu Yan Niu Edward Khomotso Nkadimeng Kazuhito Ohmi Katsunobu Oide Hideki Okawa Mohamed Ouchemhou Qun Ouyang Daniele Paesani Carlo Pagani Stathes Paganis Collette Pakuza Jiangyang Pan Juntong Pan Tong Pan Xiang Pan Papia Panda Saraswati Pandey Mila Pandurovic Rocco Paparella Roman Pasechnik Emilie Passemar r Hua Pei Xiaohua Peng Xinye Peng Yuemei Peng Jialun Ping Ronggang Ping Souvik Priyam Adhya Baohua Qi Hang Qi Huirong Qi Ming Qi Sen Qian Zhuoni Qian Congfeng Qiao Guangyou Qin Jiajia Qin Laishun Qin Liqing Qin Qin Qin Xiaoshuai Qin Zhonghua Qin Guofeng Qu Antonio Racioppi Michael Ramsey-Musolf Shabbar Raza Vladimir Rekovic Jing Ren Jirgen Reuter Tania Robens Giancarlo Rossi manqi Ruan manqi Ruan Leonid Rumyantsev Min Sang Ryu Renat Sadykov Minjing Sang Juan Jose Sanz-Cillero Miroslav Saur Nishil Savla Michael A.Schmidt Daniele Sertore Ron Settles Peng Sha Ding-Yu Shao Ligang Shao Hua-Sheng Shao Xin She Chuang Shen Hong-Fei Shen Jian-Ming Shen Peixun Shen Qiuping Shen Zhongtao Shen Shuqi Sheng Haoyu Shi Hua Shi Qi Shi Shusu Shi Xiaolei Shi Xin Shi Yukun Shi Zhan Shi Ian Shipsey Gary Shiu Chang Shu Zong-Guo Si Andrei Sidorenkov Ivan Smiljanc Aodong Song Huayang Song Jiaojiao Song Jinxing Song Siyuan Song Weimin Song Weizheng Song Zhi Song Shashwat Sourav Paolo Spruzzola Feng Su Shengsen Su Wei Su Shufang Su Yanfeng Sui Zexuan Sui Michael Sullivan Baiyang Sun Guoqiang Sun Hao Sun Hao-Kai Sun Junfeng Sun Liang Sun Mengcheng Sunl Pengfei Sun Sichun Sun Xianjing Sun Xiaohu Sun Xilei Sun Xingyang Sun Xin-Yuan Sun Yanjun Sun Yongzhao Sun Yue Sun Zheng Sun Zheng Sun Narumon Suwonjandee Elsayed Tag Eldin Biao Tan Bo Tang Chuanxiang Tang Gao Tang Guangyi Tang Jian Tang Jingyu Tang Liang Tang Ying'Ao Tang Junquan Tao Abdel Nasser Taw fik Geoffrey Taylor Valery Telnov Saike Tian Riccardo Torre Wladyslaw Henryk Trzaska Dmitri Tsybychev Yanjun Tu Shengquan Tuo Michael Tytgat Ghalib Ul Islam Nikita Ushakov German Valencia Jaap Velthuis Alessandro Vicini Trevor Vickey Ivana Vidakovic Henri Videau Raymond Volkas Dmitry Voronin Natasa Vukasinovic Xia Wan Xuying Wan Xiao Wang Anqing Wang Bin Wang Chengtao Wang Chuanye Wang Ci Wang Dayong Wang Dou Wang En Wang Fei Wang Fei Wang Guanwen Wang Guo-Li Wang Haijing Wang Haolin Wang Jia Wang Jian Wang Jianchun Wang Jianli Wang Jiawei Wang Jin Wang Jin-Wei Wang Joseph Wang Kechen Wang Lechun Wang Lei Wang Liguo Wang Lijiao Wang Lu Wang Meng Wang Na Wang Pengcheng Wang Qian Wang Qun Wang Shu Lin Wang Shudong Wang Taofeng Wang Tianhong Wang Tianyang Wang Tong Wang Wei Wang Wei Wang Xiaolong Wang Xiaolong Wang Xiaoning Wang Xiao-Ping Wang Xiongfei Wang Xujian Wang Yaping Wang Yaqian Wang Yi Wang Yiao Wang Yifang Wang Yilun Wang Yiwei Wang You-Kai Wang Yuanping Wang Yuexin Wang Yuhao Wang Yu-Ming Wang Yuting Wang Zhen Wang Zhigang Wang Weiping Wang Zeren Simon Wang Biao Wang Hui Wang Lian-Tao Wang Zihui Wang Zirui Wang Jia Wang Tong Wang Daihui Wei Shujun Wei Wei Wei Xiaomin Wei Yuanyuan Wei Yingjie Wei Liangjian Wen Xuejun Wen Yufeng Wen martin White Peter Williams Zef Wolffs William John Womersley Baona Wu Bobing Wu Guanjian Wu Jinfei Wu Lei Wu Lina Wu Linghui Wu Minlin Wu Peiwen Wu Qi Wu Qun Wu Tianya Wu Xiang Wu Xiaohong Wu Xing-Gang Wu Xuehui Wu Yaru Wu Yongcheng Wu Yuwen Wu Zhi Wu Xin Wu Lei Xia Ligang Xia Shang Xia Benhou Xiang Dao Xiang Zhiyu Xiang Bo-Wen Xiao Chu-Wen Xiao Dong Xiao Guangyan Xiao Han Xiao Meng Xiao Ouzheng Xiao Rui-Qing Xiao Xiang Xiao Yichen Xiao Ying Xiao Yu Xiao Yunlong Xiao Zhenjun Xiao Hengyuan Xiao Nian Xie Yuehong Xie Tianmu Xin Ye Xing Zhizhong Xing Da Xu Fang Xu Fanrong Xu Haisheng Xu Haocheng Xu Ji Xu Miaofu Xu Qingjin Xu Qingnian Xu Wei Xu Wei Xu Weixi Xu Xinping Xu Zhen Xu Zijun Xu Zehua Xu Yaoyuan Xu Feifei Xue Baojun Yan Bin Yan Fen Yan Fucheng Yan Jiaming Yan Liang Yan Luping Yan Qi-Shu Yan Wenbiao Yan Yupeng Yan Luping Yan Haoyue Yan Dong Yang Fengying Yang Guicheng Yang Haijun Yang Jin Min Yang Jing Yang Lan Yang Li Yang Li Lin Yang Lili Yang Litao Yang Mei Yang Qiaoli Yang Tiansen Yang Xiaochen Yang Yingjun Yang Yueling Yang Zhengyong Yang Zhenwei Yang Youhua Yang Xiancong Yang De-Liang Yao Shi Yao Lei Ye Lingxi Ye Mei Ye Rui Ye Rui Ye Yecheng Ye Vitaly Yermolchyk Kai Yi Li Yi Yang Yi Di Yin Peng-Fei Yin Shenghua Yin Ze Yin Zhongbao Yin Zhang Yinhong Hwi Dong Yoo Zhengyun You Charles Young Boxiang Yu Chenghui Yu Fusheng Yu Jie-Sheng Yu Jinqing Yu Lingda Yu Zhao-Huan Yu Felix Yu Bingrong Yu Changzheng Yuan Li Yuan Xing-Bo Yuan Youjin Yuan Junhui Yue Qian Yue Baobiao Yue Un Nisa Zaib Riccardo Zanzottera Hao Zeng Ming Zeng Jian Zhai Jiyuan Zhai Xin Zhe Zhai Xi-Jie Zhan Ben-Wei Zhang Bolun Zhang Di Zhang Guangyi Zhang Hao Zhang hong-hao Zhang Huaqiao Zhang Hui Zhang Jialiang Zhang Jianyu Zhang Jianzhong Zhang Jiehao Zhang Jielei Zhang Jingru Zhang Jinxian Zhang Junsong Zhang Junxing Zhang Lei Zhang Lei Zhang Liang Zhang Licheng Zhang Liming Zhang Linhao Zhang Luyan Zhang Mengchao Zhang Rao Zhang Shulei Zhang Wan Zhang Wenchao Zhang Xiangzhen Zhang Xiaomei Zhang Xiaoming Zhang Xiaoxu Zhang Xiaoyu Zhang Xuantong Zhang Xueyao Zhang Yang Zhang Yang Zhang Yanxi Zhang Yao Zhang Ying Zhang Yixiang Zhang Yizhou Zhang Yongchao Zhang Yu Zhang Yuan Zhang Yujie Zhang Yulei Zhang Yumei Zhang Yunlong Zhang Zhandong Zhang Zhaoru Zhang Zhen-Hua Zhang Zhenyu Zhang Zhichao Zhang Zhi-Qing Zhang Zhuo Zhang Zhiqing Zhang Cong Zhang Tianliang Zhang Luyan Zhang Guang Zhao Hongyun Zhao Jie Zhao Jingxia Zhao Jingyi Zhao Ling Zhao Luyang Zhao Mei Zhao Minggang Zhao Mingrui Zhao Qiang Zhao Ruiguang Zhao Tongxian Zhao Yaliang Zhao Ying Zhao Yue Zhao Zhiyu Zhao Zhuo Zhao Alexey Zhemchugov Hongjuan Zheng Jinchao Zheng Liang Zheng Ran Zheng shanxi zheng Xu-Chang Zheng Wang Zhile Weicai Zhong Yi-Ming Zhong Chen Zhou Daicui Zhou Jianxin Zhou Jing Zhou Jing Zhou Ning Zhou Qi-Dong Zhou Shiyu Zhou Shun Zhou Sihong Zhou Xiang Zhou Xingyu Zhou Yang Zhou Yong Zhou Yu-Feng Zhou Zusheng Zhou Demin Zhou Dechong Zhu Hongbo Zhu Huaxing Zhu Jingya Zhu Kai Zhu Pengxuan Zhu Ruilin Zhu Xianglei Zhu Yingshun Zhu Yongfeng Zhu Xiao Zhuang Xuai Zhuang Mikhail Zobov Zhanguo Zong Cong Zou Hongying Zou 《Radiation Detection Technology and Methods》 CSCD 2024年第1期I0003-I0016,1-1091,共1105页
The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international partners.The complex comprises four accelerators:a 3... The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international partners.The complex comprises four accelerators:a 30 GeV Linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The Linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs factory.In its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs bosons.Increasing the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of magnitude.This Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering aspects.Additionally,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection procedures.Construction is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 years.The commencement of experiments and data collection could potentially be initiated in the mid-2030s. 展开更多
关键词 initiated EXCEEDING PRECISE
原文传递
Neurological Abnormality Could be the First and Only Symptom of Familial Hemophagocytic Lymphohistiocytosis: Report of Two Families 被引量:1
8
作者 Yun-Ze Zhao Hua Cheng +7 位作者 Chang-Hong Ding hong-hao ma Tong-Li Han Jiu-Wei Li Dong Wang Zhi-Gang Li Tian-You Wang Rui Zhang 《Chinese Medical Journal》 SCIE CAS CSCD 2018年第24期3004-3006,共3页
To the Editor:Hemophagocytic lymphohistiocytosis (HLH)is a life-threatening disease which impacts many parts of the body including the digestive,circulatory,and respiratory systems.The central nervous system (CNS)can ... To the Editor:Hemophagocytic lymphohistiocytosis (HLH)is a life-threatening disease which impacts many parts of the body including the digestive,circulatory,and respiratory systems.The central nervous system (CNS)can also be affected,particularly in patients with familial HLH-2 (FHL-2),responsible for approximately 20% of all FHL.FHL-2 is a result of mutations to the perforin 1 (PRF1)gene,which can occur at numerous sites on the gene. 展开更多
关键词 NEUROLOGICAL ABNORMALITY SYMPTOM of FAMILIAL HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS
原文传递
Central Nervous System Involvement in 179 Chinese Children with Hemophagocytic Lymphohistiocytosis 被引量:19
9
作者 Yun-Ze Zhao Qing Zhang +7 位作者 Zhi-Gang Li Li Zhang Hong-Yun Lian hong-hao ma Dong Wang Xiao-Xi Zhao Tian-You Wang Rui Zhang 《Chinese Medical Journal》 SCIE CAS CSCD 2018年第15期1786-1792,共7页
Background: Central nervous system (CNS) involvement is found in many patients with hemophagocytic lymphohistiocytosis (HLH). In this study, we mainly analyzed neurological symptoms, imaging findings, cerebrospin... Background: Central nervous system (CNS) involvement is found in many patients with hemophagocytic lymphohistiocytosis (HLH). In this study, we mainly analyzed neurological symptoms, imaging findings, cerebrospinal fluid (CSF), and their relationship with outcomes of HLH children. Methods: Related data of 179 Chinese pediatric patients with HLH admitted to our center from January 2010 to December 2015 were analyzed retrospectively. Diagnosis and treatment were based on the H LH-2004 protocol. Two-tailed Chi-squared test was used to compare between different groups, and Kaplan-Meier survival curves were used to analyze the overall survival (OS) of patients with HLH. Results: In the present study, 21.2% (38/179) of total patients had neurological symptoms including seizure, irritability, somnolence, and unconsciousness. There were 80 (50.0%, excluding 19 patients without imaging data) patients with cranial imaging abnormalities. There were 14.7% (17/116, excluding 63 patients who did not accept lumbar puncture) of patients with abnormal CSF results. CNS involvement is defined as abnormalities in one or more of CNS symptoms, radiological findings, and CSF. Thus, 60.3% of them had CNS involvement, As for the prognosis, the median follow-up time was 3.2 years (17 lost to follow-up). The probable 3-year OS of children was higher without CNS involvement (86.0% ± 4.6%) than those with CNS involvement (68.9% ± 4.9%, hazard ratio [HR] = 2.286, P = 0.019), Among them, the probable 3-year OS of children without CNS symptoms was 76.0% ± 3.8%, higher than with CNS symptoms (59.5% ± 8.1%, HR = 2.147, P : 0.047). The 3-year OS of children with abnormal CSF was 64.7% ± 11.6%, compared with normal CSF (85.1% ± 3.7%, HR = 0.255, P = 0.038). Conclusions: HLH patients with CNS involvement might have worse outcomes compared with those without CNS involvement, and CNS symptoms and CSF changes are more important to access the prognosis than imaging abnormality. 展开更多
关键词 Central Nervous System Cerebrospinal Fluid Hemophagocytic Lymphohistiocytosis
原文传递
Clinical Research of Pulmonary Langerhans Cell Histiocytosis in Children 被引量:3
10
作者 Dong Wang Lei Cui +7 位作者 Zhi-Gang Li Li Zhang Hong-Yun Lian hong-hao ma Yun-Ze Zhao Xiao-Xi Zhao Tian-You Wang Rui Zhang 《Chinese Medical Journal》 SCIE CAS CSCD 2018年第15期1793-1798,共6页
Background: Pulmonary Langerhans cell histiocytosis (PLCH) is an interstitial primary pulmonary disease, characterized by Langerhans cell proliferation. It is easily misdiagnosed in children. This study aimed to ch... Background: Pulmonary Langerhans cell histiocytosis (PLCH) is an interstitial primary pulmonary disease, characterized by Langerhans cell proliferation. It is easily misdiagnosed in children. This study aimed to characterize the clinical manifestations and features of PLCH by retrospective analysis. Meihods: A retrospective analysis was performed in 117 PLCH patients out of 338 LCH patients who were admitted in our center from November 2006 to October 2013. Variables between two groups were compared by Mann-Whitney U-test and Chi-square test. Kaplan-Meier curves were constructed to compare the survival rates and Cox regression to evaluate the effect of risk factors. Results: The median age of PLCH group was significantly lower than that ofnon-PkCH group ( 18.63 months vs. 43.4 months, P 〈 0.001 ). All PLCH children had other organ involvement and only 11 cases (9.4%) had respiratory symptoms. The most common radiologic finding was cystic lesions (29 cases, 24.8%). Pulmonary thnction abnormalities were dominated by obstructive ventilatory dysfunction (63 cases, 82.9%). The 5-year overall survival (OS) of PECH children was 93.6% ± 2.3% and the event-free survival (EFS) was 55.7% ± 5.2%. Among the 38 cases with progressed or relapsed disease, five cases (13.2%) were due to progression or recurrence of lung damage. The 5-year OS of PECH children with "risk organ" involvement was significantly lower than those without "risk organ" involvement (86.0% ± 4.9% vs. 100%,X^2 = 8.793, P= 0.003). The difference of EFS between two groups was also significant (43.7% ± 7.7% vs. 66.3% ± 6.5%,X^2 = 5.399, P = 0.020). The "'risk organ" involvement had a significant impact on survival (hazard ratio = 1.9, P = 0.039). Conclusions: PLCH mainly occurs in young children, and only a small percentage of patients have respiratory symptoms. They generally have other organ involvement. Most of PLCH children have a good prognosis and most lung lesions could have improved or stabilized. Management of"risk organ" involvement is the key point to improving EFS. 展开更多
关键词 CHILDREN Langerhans Cell Histiocytosis LUNG
原文传递
Associations between PRF1 Ala91 Val polymorphism and risk of hemophagocytic lymphohistiocytosis: a meta-analysis based on 1366 subjects 被引量:2
11
作者 Guang-Hua Zhu Li-Ping Zhang +11 位作者 Zhi-Gang Li Ang Wei Ying Yang Yu Tian hong-hao ma Dong Wang Xiao-Xi Zhao Yun-Ze Zhao Na Li Wei Liu Tian-You Wang Rui Zhang 《World Journal of Pediatrics》 SCIE CAS CSCD 2020年第6期598-606,共9页
Background Perforin(PRF1)gene mutation can cause the onset of hemophagocytic lymphohistiocytosis(HLH).It has reported that PRFl Ala91 Val polymorphism was related with HLH risk.In the meta-analysis,we aim to evaluate ... Background Perforin(PRF1)gene mutation can cause the onset of hemophagocytic lymphohistiocytosis(HLH).It has reported that PRFl Ala91 Val polymorphism was related with HLH risk.In the meta-analysis,we aim to evaluate the association between PRF1 Ala91 Val polymorphism and HLH risk.Methods We accomplished a meta-analysis of six published case-control studies including 391 patients with HLH and 975 controls.We evaluated the quality of each study through Newcastle-Ottawa Scale(NOS).Data analysis was performed with Stata software.Results In general,all studies were of high quality(NOS score higher than 7).There were statistically significant between the PRFl Ala91 Val polymorphism and HLH risk though the pooled analysis[for Ala/Val vs.Ala/Ala:pooled odds ratio(OR)=3.22,95%confidence interval(Cl)1.08-9.56,P=0.035,random model;for Ala/Val+Val/Val vs.Ala/Ala:pooled OR=2.96,95%Cl 1.14-7.69,P=0.025,random model].Furthermore,sensitivity analysis also revealed a relationship between PRFl Ala91Val polymorphism and HLH risk(for Ala/Val vs.Ala/Ala:pooled OR=5.236,95%Cl 2.72-10.08,P<0.000,/2=12.1%,^heterogeneity=0-332;for Ala/Val+Val/Val vs.Ala/Ala,pooled OR=4.856,95%Cl 2.66-8.85,P<0.000,/2=5.9%,Pheterogeneity=0.373).Funnel plot and Egger’s test did not indicate obvious published bias(P=0.841 for Ala/Val vs.Ala/Ala;?=0.284 for Ala/Val+Val/Val vs.Ala/Ala).Conclusion This meta-analysis indicated that PRFl Ala91 Val polymorphism affects the factor for developing HLH and future studies of PRFl Ala91 Val on the onset of HLH will be guaranteed. 展开更多
关键词 Ala91Val polymorphism Hemophagocytic lymphohistiocytosis PRFl
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部