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角膜绷带镜对复发性翼状胬肉术后角膜上皮愈合和疼痛评分及角膜规则度的影响 被引量:15
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作者 朱红梅 宋峰伟 杨卫华 《国际眼科杂志》 CAS 北大核心 2018年第6期1142-1145,共4页
目的:研究角膜绷带镜对复发性翼状胬肉患者术后角膜上皮愈合、疼痛程度评分和角膜表面规则度的影响。方法:回顾性病例研究。将2015-09/2017-09就诊于湖州师范学院附属第一医院并行手术治疗的64例64眼复发性翼状胬肉患者,根据术后是否使... 目的:研究角膜绷带镜对复发性翼状胬肉患者术后角膜上皮愈合、疼痛程度评分和角膜表面规则度的影响。方法:回顾性病例研究。将2015-09/2017-09就诊于湖州师范学院附属第一医院并行手术治疗的64例64眼复发性翼状胬肉患者,根据术后是否使用角膜绷带镜分组,A组34眼术后配戴1wk角膜绷带镜,B组30眼术后不使用角膜绷带镜。采用荧光素钠角膜染色法评价翼状胬肉患者术后1d和1wk时角膜上皮愈合程度;通过视觉模拟评分法评估患者术后2h,1d,1wk时疼痛程度;采用角膜地形图系统分析术前及术后1mo时角膜表面规则指数、角膜表面不对称指数和角膜散光情况。结果:A组患者术后1d,1wk时角膜上皮愈合评分与B组相比,差异均有统计学意义(P<0.01)。A组患者术后各时间点的疼痛程度评分均明显低于B组,差异均有统计学意义(P<0.01)。A组患者术前角膜表面规则指数、角膜表面不对称指数及角膜散光与B组相比,差异无统计学意义(P>0.05),而术后1mo时角膜表面规则指数、角膜表面不对称指数及角膜散光与B组相比,差异均有统计学意义(P<0.01)。结论:复发性翼状胬肉患者术后配戴角膜绷带镜,有助于角膜上皮愈合,减轻术后刺激症状,改善角膜表面规则度,降低术后角膜散光。 展开更多
关键词 角膜绷带镜 视觉模拟评分法 角膜荧光染色 疼痛 角膜表面规则指数 角膜表面不对称指数
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Expression Patterns and Implications of LaminBl in Rat Cochleae
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作者 Zhi-hui DU Jin CHEN +8 位作者 Qing-guo CHEN Liang-qiang ZHOU Dan BING Yun LIU Yan-bo SUN Peng-jun LI Fan QI hong-mei zhu Han-qi CHU 《Current Medical Science》 SCIE CAS 2019年第2期305-309,共5页
LaminB1,a major component of the nuclear lamina,is a potent regulator of cellular proliferation and senescence and also known to be essential for neuronal migration and brain development.However,the expression pattern... LaminB1,a major component of the nuclear lamina,is a potent regulator of cellular proliferation and senescence and also known to be essential for neuronal migration and brain development.However,the expression patterns of LaminB1 in the rat cochleae are still not fully revealed.Utilizing immunofluorescence.Western blotting,and quantitative real-time PCR,we identified the distribution and expression of LaminB1 in the rat cochleae.Immunofluorescence staining indicated that LaminBl was mainly localized in the auditory hair cells(HCs),spiral ganglion cells(SGC),stria vascularis(STV,including spiral ligament),Reissner's membrane(RM),and limbus laminae spiralis(LLS).Western blotting analysis illustrated that the distribution of LaminBl in rat cochleae was characterized by tissue specificity.The LaminB1 protein was expressed more in SGC and basilar membrane(BM)than in STV.Meanwhile,the mRNA expression of LaminB1 displayed difference in cochlear tissues.These observations preliminarily revealed the expression patterns of LaminB1,providing a theoretical basis for further study on the role of LaminB1 in auditory function. 展开更多
关键词 LaminB1 cochleae RAT HAIR CELL SPIRAL GANGLION CELL stria vascularis
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Effects of Xueshuantong combined with antioxidant drugs on nerve conduction function and oxidative stress in patients with diabetic peripheral neuropathy
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作者 Yuan-Zhen Chu Zhang Yu-Mei +2 位作者 Dan Cai Wei Yan hong-mei zhu 《Journal of Hainan Medical University》 2017年第13期67-70,共4页
Objective:To study the effect of Xueshuantong combined with antioxidant drugs on nerve conduction function and oxidative stress in patients with diabetic peripheral neuropathy. Methods: 138 cases of patients with diab... Objective:To study the effect of Xueshuantong combined with antioxidant drugs on nerve conduction function and oxidative stress in patients with diabetic peripheral neuropathy. Methods: 138 cases of patients with diabetic peripheral neuropathy who were treated in endocrinology department of our hospital between June 2014 and October 2016 were enrolled and randomly divided into two groups. The combination group received Xueshuantong combined with antioxidant drug therapy, and the control group received antioxidant drug therapy. Before and after treatment, the nerve conduction velocity as well as serum content of oxidative stress indexes and nerve cytokines was measured.Results: 4 weeks and 8 weeks after treatment, common peroneal nerve and median nerve MNCV and SNCV as well as serum SOD, GSH-Px, HO-1, CAT, CNTF, BDNF and SDF-1 levels of both groups were significantly higher than those before treatment while serum MDA, AOPP and 8-OHdG levels were significantly lower than those before treatment, and common peroneal nerve and median nerve MNCV and SNCV as well as serum SOD, GSH-Px, HO-1, CAT, CNTF, BDNF and SDF-1 levels of combination group were significantly higher than those of control group while serum MDA, AOPP and 8-OHdG levels were significantly lower than those of control group.Conclusion:Xueshuantong combined with antioxidant drugs can improve the nerve conduction function, inhibit oxidative stress response and improve neurotrophy status in patients with diabetic peripheral neuropathy. 展开更多
关键词 DIABETIC PERIPHERAL NEUROPATHY XUESHUANTONG OXIDATIVE stress CYTOKINES
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