Objective:To observe the clinical effect of electroacupuncture"Tongmin point"combined with heat-sensitive moxibustion on knee osteoarthritis and its effect on blood lipid level,polyprotein polysaccharide enz...Objective:To observe the clinical effect of electroacupuncture"Tongmin point"combined with heat-sensitive moxibustion on knee osteoarthritis and its effect on blood lipid level,polyprotein polysaccharide enzyme-4(a disintegrin and metalloprotease with thrombospondin motifs,ADAMTS-4,matrix metalloproteinase-3(matrix metalloproteinase-3,);and MMPs-3)Impact.Methods:80 patients were randomly divided into two groups,40 cases per group,Treatment and control groups,The treatment group was given electroacupuncture combined with heat-sensitive moxibustion,Six times a week,Continuous treatment for 4 weeks;The control group was given intraarticular sodium hyaluronate,Once a week,continuous treatment for 4 weeks.Results:During the treatment period,Visual analogue scale visual analogue scale,VAS)show a downward trend,Intra-group comparisons,Differences were statistically significant(P<0.05);After 2 weeks of treatment,4 weeks of treatment and 2 weeks of follow-up,All the scores in the treatment group were lower than those in the control group(P<0.05).After treatment in two groups(The Western Ontario and Mc Master Universities Osteoarthritis Index,)of osteoarthritis index,University of Western Ontario WOMAC)The scores of each item decreased significantly,treatment group was better than the control group(P<0.05).After four weeks of treatment,(Total cholesterol,)Total cholesterol TC,triglycerides(Triglyceride,);and TG,LDL(Low density lipoprotein,);and LDL-C)A decrease in content,High density lipoprotein High density lipoprotein,HDL-C)Increased content,and the improvement was better than that of the control group(P<0.05).After treatment,the ADAMTS-4,MMPs-3 content decreased,Intergroup comparisons,Differences were statistically significant(P<0.05);The effective rate in the treatment group was 87.5%,The control rate was 60%,treatment group was more effective(P<0.05).Conclusions:Electroacupuncture"Tongmin point"combined with heat-sensitive moxibustion can obviously improve the symptoms of knee osteoarthritis patients,Regulate blood lipids,High security,It is worth popularizing in clinic.展开更多
In this work,a novel bisbenzimidazolylpyridine-functionalized fluorescent epoxy resin was synthesized for organophosphate pesticide detection.The epoxy resin was characterized by Fourier-transform infrared spectroscop...In this work,a novel bisbenzimidazolylpyridine-functionalized fluorescent epoxy resin was synthesized for organophosphate pesticide detection.The epoxy resin was characterized by Fourier-transform infrared spectroscopy(FT-IR),proton nuclear magnetic resonance spectroscopy(~1H NMR),gel permeation chromatography(CPC),differential scanning calorimetry(DSC) and fluorescence spectroscopy.After loading with Eu(Ⅲ) ions,the epoxy resin showed a strong fluorescence emission.The fluorescence emission was observed to be instantaneously quenched when exposed to trace amount of diethyl chlorophosphate in solution.The Stern-Volmer quenching constants Ksv for quenching at617 nm was determined to be 0.377 × 10^3 L/mol.This sensitive emission-quenching function and easy processing nature of the polymeric support enable the resin to be a promising chemosensor candidate for the detection of organophosphates.展开更多
Objective:To analyze the efficacy and safety of moxibustion(A kind of complementary and alternative methods of traditional Chinese medicine)for the Functional dyspepsia(FD).Methods:Six electronic databases were search...Objective:To analyze the efficacy and safety of moxibustion(A kind of complementary and alternative methods of traditional Chinese medicine)for the Functional dyspepsia(FD).Methods:Six electronic databases were searched for randomized controlled trials investigating the efficacy of moxibustion in the treatment of FD.The search period was from inception to February 25,2019.Eligible reports of RCT on the moxibustion compare with medication were enrolled.Article's quality was evaluated with the Cochrane Risk Bias Tool in the Cochrane Handbook by two independent reviewers.The Review Manager 5.3 was used to evaluate the publication bias.Result:Eleven eligible reports comprising a total of 870 participants were enrolled.The risk of bias was generally high.In the primary outcome,compared with medications,moxibustion significantly alleviated overall FD symptoms but there was a moderate inconsistency among studies(11 RCTs,RR=1.27,95% CI[1.20,1.36]).Moxibustion appears to be associated with few adverse events but the evidence is limited due to poor report quality.Conclusion:Moxibustion showed greater improvement in terms of clinical efficacy in the treatment of FD than pharmacological medications,and although it was not possible to draw a definitive conclusion due to the small sample size,high risk of bias,and low quality of the reports.Large multi-center and long-term high-quality randomized control trials are needed.展开更多
Shallow lakes are an important part of the earth's water circulation system, and many factors may impact the evolution of the lake water circulation, including the wind, the topography, the human activities, and t...Shallow lakes are an important part of the earth's water circulation system, and many factors may impact the evolution of the lake water circulation, including the wind, the topography, the human activities, and the aquatic plants. This paper proposes a depth-averaged 2-D hydrodynamic model to investigate the interaction of the wind-induced current and the aquatic plant in the lake. The model is based on the generalized shallow water equations solved by an explicit finite volume method with unstructured triangular grids. The drag force of the vegetation is considered into the momentum equations as the source term. Remote sensing techniques are applied to evaluate the aquatic vegetation in the Taihu Lake, China, based on Landsat TM satellite images. The study model is then used to simulate the characteristics of the wind-induced currents in the Taihu Lake, without and with the vegetation effects. The simulation results are in good agreement with the field measurements, demonstrating that the aquatic plants significantly affect the magnitude of the velocity and the flow circulation induced by the wind in the Taihu Lake. In addition, a sensitivity analysis reveals that the plant parameters (the density and the drag force coefficient) are significant factors influencing the velocity and the structure of the currents in the Taihu Lake.展开更多
基金Clinical Medical Research Project of Wuhan Municipal Health and Family Planning Commission(No.WZ20Q12)Major project of the National Natural Science Foundation of China"Clinical Application Research on Different Functional States of Acupoints"(No.81590955)。
文摘Objective:To observe the clinical effect of electroacupuncture"Tongmin point"combined with heat-sensitive moxibustion on knee osteoarthritis and its effect on blood lipid level,polyprotein polysaccharide enzyme-4(a disintegrin and metalloprotease with thrombospondin motifs,ADAMTS-4,matrix metalloproteinase-3(matrix metalloproteinase-3,);and MMPs-3)Impact.Methods:80 patients were randomly divided into two groups,40 cases per group,Treatment and control groups,The treatment group was given electroacupuncture combined with heat-sensitive moxibustion,Six times a week,Continuous treatment for 4 weeks;The control group was given intraarticular sodium hyaluronate,Once a week,continuous treatment for 4 weeks.Results:During the treatment period,Visual analogue scale visual analogue scale,VAS)show a downward trend,Intra-group comparisons,Differences were statistically significant(P<0.05);After 2 weeks of treatment,4 weeks of treatment and 2 weeks of follow-up,All the scores in the treatment group were lower than those in the control group(P<0.05).After treatment in two groups(The Western Ontario and Mc Master Universities Osteoarthritis Index,)of osteoarthritis index,University of Western Ontario WOMAC)The scores of each item decreased significantly,treatment group was better than the control group(P<0.05).After four weeks of treatment,(Total cholesterol,)Total cholesterol TC,triglycerides(Triglyceride,);and TG,LDL(Low density lipoprotein,);and LDL-C)A decrease in content,High density lipoprotein High density lipoprotein,HDL-C)Increased content,and the improvement was better than that of the control group(P<0.05).After treatment,the ADAMTS-4,MMPs-3 content decreased,Intergroup comparisons,Differences were statistically significant(P<0.05);The effective rate in the treatment group was 87.5%,The control rate was 60%,treatment group was more effective(P<0.05).Conclusions:Electroacupuncture"Tongmin point"combined with heat-sensitive moxibustion can obviously improve the symptoms of knee osteoarthritis patients,Regulate blood lipids,High security,It is worth popularizing in clinic.
基金Financial supports from the Research Foundation of the General Armament Department(No.2008 CD 012) are gratefully acknowledged
文摘In this work,a novel bisbenzimidazolylpyridine-functionalized fluorescent epoxy resin was synthesized for organophosphate pesticide detection.The epoxy resin was characterized by Fourier-transform infrared spectroscopy(FT-IR),proton nuclear magnetic resonance spectroscopy(~1H NMR),gel permeation chromatography(CPC),differential scanning calorimetry(DSC) and fluorescence spectroscopy.After loading with Eu(Ⅲ) ions,the epoxy resin showed a strong fluorescence emission.The fluorescence emission was observed to be instantaneously quenched when exposed to trace amount of diethyl chlorophosphate in solution.The Stern-Volmer quenching constants Ksv for quenching at617 nm was determined to be 0.377 × 10^3 L/mol.This sensitive emission-quenching function and easy processing nature of the polymeric support enable the resin to be a promising chemosensor candidate for the detection of organophosphates.
基金Supported by National Natural Science Foundation of China:81473790
文摘Objective:To analyze the efficacy and safety of moxibustion(A kind of complementary and alternative methods of traditional Chinese medicine)for the Functional dyspepsia(FD).Methods:Six electronic databases were searched for randomized controlled trials investigating the efficacy of moxibustion in the treatment of FD.The search period was from inception to February 25,2019.Eligible reports of RCT on the moxibustion compare with medication were enrolled.Article's quality was evaluated with the Cochrane Risk Bias Tool in the Cochrane Handbook by two independent reviewers.The Review Manager 5.3 was used to evaluate the publication bias.Result:Eleven eligible reports comprising a total of 870 participants were enrolled.The risk of bias was generally high.In the primary outcome,compared with medications,moxibustion significantly alleviated overall FD symptoms but there was a moderate inconsistency among studies(11 RCTs,RR=1.27,95% CI[1.20,1.36]).Moxibustion appears to be associated with few adverse events but the evidence is limited due to poor report quality.Conclusion:Moxibustion showed greater improvement in terms of clinical efficacy in the treatment of FD than pharmacological medications,and although it was not possible to draw a definitive conclusion due to the small sample size,high risk of bias,and low quality of the reports.Large multi-center and long-term high-quality randomized control trials are needed.
基金Project supported by the National Nature Science Foundation of China (Grant No. 51779039, 51879028)supported by the Wetland Degra-dation and Ecological Restoration Program of Panjin Pink Beach (Grant No. PHL-XZ-2017013-002)the Fund of Liaoning Marine Fishery Department (Grant No. 201725).
文摘Shallow lakes are an important part of the earth's water circulation system, and many factors may impact the evolution of the lake water circulation, including the wind, the topography, the human activities, and the aquatic plants. This paper proposes a depth-averaged 2-D hydrodynamic model to investigate the interaction of the wind-induced current and the aquatic plant in the lake. The model is based on the generalized shallow water equations solved by an explicit finite volume method with unstructured triangular grids. The drag force of the vegetation is considered into the momentum equations as the source term. Remote sensing techniques are applied to evaluate the aquatic vegetation in the Taihu Lake, China, based on Landsat TM satellite images. The study model is then used to simulate the characteristics of the wind-induced currents in the Taihu Lake, without and with the vegetation effects. The simulation results are in good agreement with the field measurements, demonstrating that the aquatic plants significantly affect the magnitude of the velocity and the flow circulation induced by the wind in the Taihu Lake. In addition, a sensitivity analysis reveals that the plant parameters (the density and the drag force coefficient) are significant factors influencing the velocity and the structure of the currents in the Taihu Lake.