Objective:To systematically evaluate the efficacy and safety of Guipi Decoction combined with Western medicine in the treatment of insomnia with deficiency of heart and spleen.Methods:English databases(PubMed,Web of S...Objective:To systematically evaluate the efficacy and safety of Guipi Decoction combined with Western medicine in the treatment of insomnia with deficiency of heart and spleen.Methods:English databases(PubMed,Web of Science,The Cochrane Library,EMBASE)and Chinese databases(CNKI,Wanfang database,China Biomedical Literature Service System,VIP database)were searched by computer.Randomized controlled trials of Guipi Decoction on insomnia with deficiency of heart and spleen were searched from the database construction to November 2021.After the first and second authors independently screened the literature,extracted the data and evaluated the risk of bias in the included studies,meta-analysis was performed using RevMan5.3 software.Results:A total of 9 RCTS were included after screening,including 914 patients.Meta-analysis results showed that:Total effective rate[RR=1.22,95%CI(1.16,1.30),P<0.00001],total PSQI score[MD=-3.05,95%CI(-3.96,-2.14),P=0.008],number of night awakening times[[MD=-1.18,95%CI(-1.42,-0.94),P<0.00001],adverse reaction rate[RR=0.32,95%CI(0.21,0.51),P<0.00001]were better than the control group,and the differences were statistically significant.Conclusion:The current evidence shows that,compared with pure using conventional western medicine,belongs to the spleen decoction combined western medicine therapy,cases both deficiency type of insomnia in the total effective rate,reducing the total PSQI score(improve sleep quality,sleep efficiency,sleep disorder,daytime function,etc.),reducing frequency of nighttime awakening,security,have more advantages.However,due to the limitation of the quality and quantity of articles included in the study,more randomized,double-blind,large-sample clinical studies are needed to confirm the above conclusions.展开更多
LA-ICP MS zircon U-Pb dating results of granites from Sawuer Mountains in North Xinjiang, NW China, are reported based on 1：50 000 regional geologic surveys. Zircon U-Pb dating shows that the granitoids have magmatic...LA-ICP MS zircon U-Pb dating results of granites from Sawuer Mountains in North Xinjiang, NW China, are reported based on 1：50 000 regional geologic surveys. Zircon U-Pb dating shows that the granitoids have magmatic crystallization age of 320 ± 2 Ma. In addition, zircons with ages of 341 -358 Ma could be subdivided into two groups, i. e. , Group 1 with a weighted mean age of 342 ± 3 Ma and Group 2 with a weighted mean age of 354 ± 2 Ma. The petrology and geochemistry of granitoids from Sawuer Mountains suggest their mixed origin. The granite from Sawuer Mountains occurred in an extensional setting, most probably related to post-orogenic processes during the closure of the Peo-Asian Ocean ; namely, represent the tectonic setting shifted from compress to post-collisional setting.展开更多
文摘Objective:To systematically evaluate the efficacy and safety of Guipi Decoction combined with Western medicine in the treatment of insomnia with deficiency of heart and spleen.Methods:English databases(PubMed,Web of Science,The Cochrane Library,EMBASE)and Chinese databases(CNKI,Wanfang database,China Biomedical Literature Service System,VIP database)were searched by computer.Randomized controlled trials of Guipi Decoction on insomnia with deficiency of heart and spleen were searched from the database construction to November 2021.After the first and second authors independently screened the literature,extracted the data and evaluated the risk of bias in the included studies,meta-analysis was performed using RevMan5.3 software.Results:A total of 9 RCTS were included after screening,including 914 patients.Meta-analysis results showed that:Total effective rate[RR=1.22,95%CI(1.16,1.30),P<0.00001],total PSQI score[MD=-3.05,95%CI(-3.96,-2.14),P=0.008],number of night awakening times[[MD=-1.18,95%CI(-1.42,-0.94),P<0.00001],adverse reaction rate[RR=0.32,95%CI(0.21,0.51),P<0.00001]were better than the control group,and the differences were statistically significant.Conclusion:The current evidence shows that,compared with pure using conventional western medicine,belongs to the spleen decoction combined western medicine therapy,cases both deficiency type of insomnia in the total effective rate,reducing the total PSQI score(improve sleep quality,sleep efficiency,sleep disorder,daytime function,etc.),reducing frequency of nighttime awakening,security,have more advantages.However,due to the limitation of the quality and quantity of articles included in the study,more randomized,double-blind,large-sample clinical studies are needed to confirm the above conclusions.
文摘LA-ICP MS zircon U-Pb dating results of granites from Sawuer Mountains in North Xinjiang, NW China, are reported based on 1：50 000 regional geologic surveys. Zircon U-Pb dating shows that the granitoids have magmatic crystallization age of 320 ± 2 Ma. In addition, zircons with ages of 341 -358 Ma could be subdivided into two groups, i. e. , Group 1 with a weighted mean age of 342 ± 3 Ma and Group 2 with a weighted mean age of 354 ± 2 Ma. The petrology and geochemistry of granitoids from Sawuer Mountains suggest their mixed origin. The granite from Sawuer Mountains occurred in an extensional setting, most probably related to post-orogenic processes during the closure of the Peo-Asian Ocean ; namely, represent the tectonic setting shifted from compress to post-collisional setting.
