Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of eme...Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in China, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up.展开更多
Syncope is defined as a transient loss of consciousness due to global cerebral hypoperfusion, accompanied by loss of muscle tone and failure to maintain an active position. Vasovagal syncope (VVS) is the most common p...Syncope is defined as a transient loss of consciousness due to global cerebral hypoperfusion, accompanied by loss of muscle tone and failure to maintain an active position. Vasovagal syncope (VVS) is the most common presentation of syncope, and its diagnostic criteria include:(1) absence of any other evident etiology for syncope or presyncope,(2) positive response to head-up tilt test with evident vasovagal reaction (hypotension and/or bradycardia), and (3) no concomitant chronic or acute disease [1, 2]. The onset of VVS peaks initially in childhood and adolescence, and accounts for 60%–70% of all syncopal cases. Clinicians pay great attention to syncope among children and adolescents, due to its high prevalence and its impact on patients’ quality of life. Affected individuals often experience mental stress, economic burdens, and accidental bodily injuries related to syncope [2]. While the pathogenesis of VVS is not fully understood, autonomic nervous dysfunction has been identified as a contributing mechanism. The examination of autonomic nervous function can provide important information about patients with syncope.展开更多
Syncope,a transient loss of consciousness due to global cerebral hypoperfusion,is common in the young.Around 15%–20%of children and adolescents experience at least one episode of syncope,which greatly impacts their l...Syncope,a transient loss of consciousness due to global cerebral hypoperfusion,is common in the young.Around 15%–20%of children and adolescents experience at least one episode of syncope,which greatly impacts their life quality.Therefore,continuous improvement of the management of syncope is an important issue in the field.On August 24th,2019,the 7th congress on pediatric syncope in China was held in Changsha,China.Over 300 participants from 11 countries attended the conference,at which the treatment progress of pediatric syncope was actively discussed.展开更多
Sitting intolerance refers to a series of symptoms(e.g.,dizziness,headache,blurred vision,chest tightness,nausea,abdominal pain,numbness,and syncope)induced by sedentariness or a sudden transition from a supine positi...Sitting intolerance refers to a series of symptoms(e.g.,dizziness,headache,blurred vision,chest tightness,nausea,abdominal pain,numbness,and syncope)induced by sedentariness or a sudden transition from a supine position to a sitting position.1,2 Many investigations regarding the pathogenesis,clinical manifestation,diagnosis,and treatment of orthostatic intolerance have been conducted in recent years,but little is known about these issues with respect to sitting intolerance among children and adolescents.Notably,sitting syncope is not rare among adults with a history of syncope.In a study of 111 adult patients,Khadilkar et al.展开更多
文摘Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in China, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up.
基金supported by the Science and Technology Program of Beijing Municipality, China (Z171100001017253)Peking University Clinical Scientist Program, China (BMU2019LCKXJ001)
文摘Syncope is defined as a transient loss of consciousness due to global cerebral hypoperfusion, accompanied by loss of muscle tone and failure to maintain an active position. Vasovagal syncope (VVS) is the most common presentation of syncope, and its diagnostic criteria include:(1) absence of any other evident etiology for syncope or presyncope,(2) positive response to head-up tilt test with evident vasovagal reaction (hypotension and/or bradycardia), and (3) no concomitant chronic or acute disease [1, 2]. The onset of VVS peaks initially in childhood and adolescence, and accounts for 60%–70% of all syncopal cases. Clinicians pay great attention to syncope among children and adolescents, due to its high prevalence and its impact on patients’ quality of life. Affected individuals often experience mental stress, economic burdens, and accidental bodily injuries related to syncope [2]. While the pathogenesis of VVS is not fully understood, autonomic nervous dysfunction has been identified as a contributing mechanism. The examination of autonomic nervous function can provide important information about patients with syncope.
文摘Syncope,a transient loss of consciousness due to global cerebral hypoperfusion,is common in the young.Around 15%–20%of children and adolescents experience at least one episode of syncope,which greatly impacts their life quality.Therefore,continuous improvement of the management of syncope is an important issue in the field.On August 24th,2019,the 7th congress on pediatric syncope in China was held in Changsha,China.Over 300 participants from 11 countries attended the conference,at which the treatment progress of pediatric syncope was actively discussed.
基金This work was supported by the National High-Level Hospital Clinical Research Funding(Multi-center Clinical Research Project of Peking University First Hospital)(2022CR59).
文摘Sitting intolerance refers to a series of symptoms(e.g.,dizziness,headache,blurred vision,chest tightness,nausea,abdominal pain,numbness,and syncope)induced by sedentariness or a sudden transition from a supine position to a sitting position.1,2 Many investigations regarding the pathogenesis,clinical manifestation,diagnosis,and treatment of orthostatic intolerance have been conducted in recent years,but little is known about these issues with respect to sitting intolerance among children and adolescents.Notably,sitting syncope is not rare among adults with a history of syncope.In a study of 111 adult patients,Khadilkar et al.