OBJECTIVE It has been recognized that HBV infection andalcohol consumption are two important risk factors for primaryhepatocellular carcinoma (HCC). Recently, the role of clonorchiasisas a risk factor for HCC is contr...OBJECTIVE It has been recognized that HBV infection andalcohol consumption are two important risk factors for primaryhepatocellular carcinoma (HCC). Recently, the role of clonorchiasisas a risk factor for HCC is controversial. We aimed to investigatewhether these factors increase the risk of HCC in Guangxi, China.METHODS A hospital-based, case-control study of HCCwas conducted from July 2005 to July 2007. We enrolled 500consecutive patients with HCC as an experimental group and 500patients without tumor in liver as a control group. The risk factorsthat the patients were exposed to were assessed.RESULTS Comparing the risks of developing the HCC, wefound out the following results. The risk of developing HCC forthe patients with clonorchiasis was 5 folds of that for the patientswithout clonorchiasis (OR = 5.0; 95% CI: 3.1-8.1), and the risk forthe patients with alcohol consumption was 3 folds of that for thepatients without drinking alcohol (OR = 3.4; 95% CI: 2.3-4.9), andsimilarly, the risk for the patients with HBV infection was 21 timesof that for the patients without HBV infection (OR = 20.6; 95% CI:14.3-29.7). According to crossover analysis, there was significantinteraction among clonorchiasis, HBV infection and alcoholconsumption, with synergistic indices greater than 1. The etiologicfractions attributed to these interactions [EF (A x B)] are 0.7465,0.5789 and 0.5506, respectively.CONCLUSION Clonorchiasis, HBV infection and heavy alcoholconsumption are independent risk factors for developing HCC inour population in Guangxi, and as they can interact synergistically,the risk of developing HCC is increased. Data from this study mayindicate new prevention strategies of developing HCC in high-riskindividuals.展开更多
This paper investigates the performance of T-stub connected semi-rigid joint of rectangular tubular columns and H-shaped steel beams.The finite element analysis software ABAQUS is used to analyze the nonlinear perform...This paper investigates the performance of T-stub connected semi-rigid joint of rectangular tubular columns and H-shaped steel beams.The finite element analysis software ABAQUS is used to analyze the nonlinear performance of the joint under monotonic loading.Meanwhile,the dimensions of T-stub,column and beam are considered as analytic parameters to discuss the performance of the joint.The analysis shows that the thickness and the length of T-stub webs,the height of beam section,bolt diameter,shear connector and the preloaded force affect the performance of the joint largely,and the thickness of the steel tube,the thickness and length of T-stub flange,bolt spacing have relatively little influences on the performance of the joint.The research results indicate that this joint is semi-rigid joint.展开更多
基金supported by a grant from the National Natural Science Foundation of China(No.30660162).
文摘OBJECTIVE It has been recognized that HBV infection andalcohol consumption are two important risk factors for primaryhepatocellular carcinoma (HCC). Recently, the role of clonorchiasisas a risk factor for HCC is controversial. We aimed to investigatewhether these factors increase the risk of HCC in Guangxi, China.METHODS A hospital-based, case-control study of HCCwas conducted from July 2005 to July 2007. We enrolled 500consecutive patients with HCC as an experimental group and 500patients without tumor in liver as a control group. The risk factorsthat the patients were exposed to were assessed.RESULTS Comparing the risks of developing the HCC, wefound out the following results. The risk of developing HCC forthe patients with clonorchiasis was 5 folds of that for the patientswithout clonorchiasis (OR = 5.0; 95% CI: 3.1-8.1), and the risk forthe patients with alcohol consumption was 3 folds of that for thepatients without drinking alcohol (OR = 3.4; 95% CI: 2.3-4.9), andsimilarly, the risk for the patients with HBV infection was 21 timesof that for the patients without HBV infection (OR = 20.6; 95% CI:14.3-29.7). According to crossover analysis, there was significantinteraction among clonorchiasis, HBV infection and alcoholconsumption, with synergistic indices greater than 1. The etiologicfractions attributed to these interactions [EF (A x B)] are 0.7465,0.5789 and 0.5506, respectively.CONCLUSION Clonorchiasis, HBV infection and heavy alcoholconsumption are independent risk factors for developing HCC inour population in Guangxi, and as they can interact synergistically,the risk of developing HCC is increased. Data from this study mayindicate new prevention strategies of developing HCC in high-riskindividuals.
基金This project was supported by Shenyang Technology Development Program(F11-166-9-00)Liaoning Key Laboratory Program(LS2010134)+1 种基金Liaoning Bai Qian Wan Talents Program(2009921095)Technology Program of Ministry of Housing and Urban-Rural Development(2011-k3-23).
文摘This paper investigates the performance of T-stub connected semi-rigid joint of rectangular tubular columns and H-shaped steel beams.The finite element analysis software ABAQUS is used to analyze the nonlinear performance of the joint under monotonic loading.Meanwhile,the dimensions of T-stub,column and beam are considered as analytic parameters to discuss the performance of the joint.The analysis shows that the thickness and the length of T-stub webs,the height of beam section,bolt diameter,shear connector and the preloaded force affect the performance of the joint largely,and the thickness of the steel tube,the thickness and length of T-stub flange,bolt spacing have relatively little influences on the performance of the joint.The research results indicate that this joint is semi-rigid joint.
