Investigating the Thermal Stress of Millisecond Pulsed Laser Irradiation on Charge-Coupled Devices

In this study, a two-dimensional model describing thermal stress on a charge-coupled device (CCD) induced by ms laser pulses was examined. Considering the nonlinearity of the CCD’s material parameters and the melting phase transition process of aluminum electrode materials was considered by using equivalent specific heat capacity method, the physical process where a laser pulse irradiating a CCD pixel array was simulated using COMSOL Multiphysics software. The temperature field and thermal stress field were calculated and analyzed. In order to clarify the mechanism producing damage on the CCD detector, Raman spectra from silicon were measured with a micro-Raman spectrometer to determine stress change in the CCD chip. The procedure presented herein illustrates a method for evaluating strain in a CCD after laser irradiation.

Isolation and Identification of an Insecticidal Compound from Streptomyces sp. HBUM 174093

[Objective]This study aimed to isolate and identify the insecticidal compound produced by the Streptomyces strain.[Method]Extraction,PTLC,HPLC,and other instrumental analysis were applied to obtain the bioactive compound.[Result]Yellow-white crystals were obtained and their MS and NMR spectra were analyzed.[Conclusion]Crystals were identified as the analogue of dimeric dinactin.

Inversion and Error Analysis of Target Material Proportion from Scattering Spectrum

In this work, we have proposed a scattering spectra-based method for inverting the surface materials and material proportions of space objects (SOs) from long distances. The results of this work shall improve efforts to characterize and predict the orbits of space debris. We first constructed a physical model for SO characterization based on scattering spectra and then provided a least-squares solution with minimum-norm (LSMN) algorithm for inverting the surface materials and material proportions of an SO. The optical reflectance of complex material surfaces was characterized using a bidirectional reflectance distribution function (BRDF)-based multimodal fusion model that uses the characteristics of the light source, the reflectance of the target’s surface materials, and structures, and the angle of incidence and reflection. The area of each material in the BRDF was then treated as the to-be-inverted parameter. The proposed method was then experimentally validated using four sets of materials. The materials and proportions of equiproportional and non-equiproportional combinations of materials were inverted by the proposed method, and the average inversion error was less than 10%. According to the relationship curve be-tween experimental data error and inversion error, and between theoretical error and inversion error, it can be concluded that the accuracy of inversion error has a linear relationship with the measurement data error. In summary, we have provided a new technical approach for the inversion and characterization of SO materials and material proportions from long distances.

Weakened humoral immune responses of inactivated SARS-CoV-2 vaccines in patients with solid tumors

Dear Editor Coronavirus disease 19(COVID-19),caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),remains a pandemic.Cancer patients have a higher risk of poor outcomes for SARS-CoV-2 infection than the general population[1].Vaccines were shown to effectively prevent SARS-CoV-2 infection,severe disease progression,and mortality.Inactivated SARS-CoV-2 vaccines(BBIBPCorV and CoronaVac)have been approved and widely used in China,with the former shown to be more effective than the latter[2].Hence,there is an urgent need to investigate the safety and humoral immune responses of inactivated vaccines in cancer patients.