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A novel package system based on an EBV replicon vector for producing high titer recombinant adeno-associated virus vector
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作者 Yan, ZY Yao, EM +2 位作者 Zhang, T Shu, YL hou, yd 《Chinese Science Bulletin》 SCIE EI CAS 1997年第20期1741-1744,共4页
ADENO-ASSOCIATED virus (AAV) was a human parvovirus considered as a gene delivery vehiclefor human gene therapy. Recombinant AAV vector (rAAV) could mediate the foreign DNAintegration into chromosome and establish a s... ADENO-ASSOCIATED virus (AAV) was a human parvovirus considered as a gene delivery vehiclefor human gene therapy. Recombinant AAV vector (rAAV) could mediate the foreign DNAintegration into chromosome and establish a stable expression in the infected cells. As a viraltransduction vector, rAAV was superior to the traditional retrovirus vector for its high safety.no pathogenicity, and capacity of infecting postmitosis cells. The current strategy for produc- 展开更多
关键词 RECOMBINANT AAV VECTOR EBV REPLICON VECTOR PACKAGE cell line.
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