Helicobacter pylori(H.pylori)has long been believed to be the major colonizer of the stomach,but recent advances in genetic sequencing have allowed for further differentiation of the gastric microbiome and revealed th...Helicobacter pylori(H.pylori)has long been believed to be the major colonizer of the stomach,but recent advances in genetic sequencing have allowed for further differentiation of the gastric microbiome and revealed the true complexity of the gastric microbiome.One of the few studies specifically evaluated the microbiome in the H.pylori negative patient population.They concluded that various stages of gastric carcinogenesis are associated with distinct bacterial taxa that could service both a predictive and diagnostic purpose.While the study has some limitations,the conclusions they make are intriguing and should prompt a larger prospective study to be done that spans multiple geographic regions.展开更多
Endoscopy is a complex procedure that requires advanced training and a highly skilled practitioner.The advances in the field of endoscopy have made it an invaluable diagnostic tool,but the procedure remains provider d...Endoscopy is a complex procedure that requires advanced training and a highly skilled practitioner.The advances in the field of endoscopy have made it an invaluable diagnostic tool,but the procedure remains provider dependent.The quality of endoscopy may vary from provider to provider and,as a result,is not perfect.Consequently,11.3%of upper gastrointestinal neoplasms are missed on the initial upper endoscopy and 2.1%-5.9%of colorectal polyps or cancers are missed on colonoscopy.Pathology is overlooked if endoscopic exam is not done carefully,bypassing proper visualization of the scope’s entry and exit points or,if exam is not taken to completion,not visualizing the most distal bowel segments.We hope to shed light on this issue,establish areas of weakness,and propose possible solutions and preventative measures.展开更多
文摘Helicobacter pylori(H.pylori)has long been believed to be the major colonizer of the stomach,but recent advances in genetic sequencing have allowed for further differentiation of the gastric microbiome and revealed the true complexity of the gastric microbiome.One of the few studies specifically evaluated the microbiome in the H.pylori negative patient population.They concluded that various stages of gastric carcinogenesis are associated with distinct bacterial taxa that could service both a predictive and diagnostic purpose.While the study has some limitations,the conclusions they make are intriguing and should prompt a larger prospective study to be done that spans multiple geographic regions.
文摘Endoscopy is a complex procedure that requires advanced training and a highly skilled practitioner.The advances in the field of endoscopy have made it an invaluable diagnostic tool,but the procedure remains provider dependent.The quality of endoscopy may vary from provider to provider and,as a result,is not perfect.Consequently,11.3%of upper gastrointestinal neoplasms are missed on the initial upper endoscopy and 2.1%-5.9%of colorectal polyps or cancers are missed on colonoscopy.Pathology is overlooked if endoscopic exam is not done carefully,bypassing proper visualization of the scope’s entry and exit points or,if exam is not taken to completion,not visualizing the most distal bowel segments.We hope to shed light on this issue,establish areas of weakness,and propose possible solutions and preventative measures.
