[Objective] The paper was to study the metroptosis pathogenesis of dairy buffalo.[Method]A total of 53 dairy buffaloes were selected to detect serum calcium,phosphorus,malondialdehyde（MDA） and total antioxidant capa...[Objective] The paper was to study the metroptosis pathogenesis of dairy buffalo.[Method]A total of 53 dairy buffaloes were selected to detect serum calcium,phosphorus,malondialdehyde（MDA） and total antioxidant capacity（TAC） levels.Dairy buffaloes were divided into metroptosis group（M） and healthy control group（UM） according to metroptosis situations of buffalo.The correlation between metroptosis of buffalo and calcium,phosphorus and oxidation/antioxidation levels in plasma was analyzed.[Result] The contents of serum calcium and phosphorus and oxidation/antioxidation level of dairy buffalo at the prenatal week and the calving day in M group were significantly lower than that in UM group.The TAC level of dairy buffalo in M group from the first three weeks to the calving day was significantly lower than that in UM group.The MDA level in M group was significantly higher than that in UM group.[Conclusion] The occurrence of postpartum metroptosis in buffalo was related to insufficient levels of calcium and phosphorus in prepartum buffalo,declined total antioxidation capacity and accumulation of peroxide products.展开更多
目的评价青岛市儿童水痘减毒活疫苗(Varicella attenuated live vaccine,VarV)的保护效果(Vaccine effectiveness,VE)。方法采用病例对照研究设计,选择青岛市14所学校48个班级的6-13岁学生,将2013-2018年有、无水痘发病史的学生分别纳...目的评价青岛市儿童水痘减毒活疫苗(Varicella attenuated live vaccine,VarV)的保护效果(Vaccine effectiveness,VE)。方法采用病例对照研究设计,选择青岛市14所学校48个班级的6-13岁学生,将2013-2018年有、无水痘发病史的学生分别纳入病例组、对照组,收集水痘发病和VarV接种信息,计算VarV的VE。结果本研究纳入532例水痘病例和1 596例对照。VarV的总体VE为51.7%(95%CI:40.9%-60.6%);接种1剂次、2剂次VarV的VE分别为44.4%(95%CI:31.5%-54.8%)、81.8%(95%CI:71.0%-88.6%)。在接种1剂次VarV后0-2、3-4、5-6、7-8、≥9年的VE分别为90.1%、64.8%、50.2%、40.8%、34.5%。结论儿童接种1剂次VarV的保护效果较差,且随着接种后时间的推移而递减;建议适龄儿童接种2剂次VarV,并纳入国家免疫规划。展开更多
文摘[Objective] The paper was to study the metroptosis pathogenesis of dairy buffalo.[Method]A total of 53 dairy buffaloes were selected to detect serum calcium,phosphorus,malondialdehyde（MDA） and total antioxidant capacity（TAC） levels.Dairy buffaloes were divided into metroptosis group（M） and healthy control group（UM） according to metroptosis situations of buffalo.The correlation between metroptosis of buffalo and calcium,phosphorus and oxidation/antioxidation levels in plasma was analyzed.[Result] The contents of serum calcium and phosphorus and oxidation/antioxidation level of dairy buffalo at the prenatal week and the calving day in M group were significantly lower than that in UM group.The TAC level of dairy buffalo in M group from the first three weeks to the calving day was significantly lower than that in UM group.The MDA level in M group was significantly higher than that in UM group.[Conclusion] The occurrence of postpartum metroptosis in buffalo was related to insufficient levels of calcium and phosphorus in prepartum buffalo,declined total antioxidation capacity and accumulation of peroxide products.
