Dear Editor,Alternative splicing (AS) of pre-mRNA is an evolutionarily conserved mechanism to increase transcriptomic and proteomic complexity, and hence phenotypic diversity, via the production of multiple mRNA iso...Dear Editor,Alternative splicing (AS) of pre-mRNA is an evolutionarily conserved mechanism to increase transcriptomic and proteomic complexity, and hence phenotypic diversity, via the production of multiple mRNA isoforms from a single gene (Reddy et al., 2013). AS is regulated by various cis-acting regulatory elements and RNA-binding proteins (Reddy et al., 2013).展开更多
文摘Dear Editor,Alternative splicing (AS) of pre-mRNA is an evolutionarily conserved mechanism to increase transcriptomic and proteomic complexity, and hence phenotypic diversity, via the production of multiple mRNA isoforms from a single gene (Reddy et al., 2013). AS is regulated by various cis-acting regulatory elements and RNA-binding proteins (Reddy et al., 2013).