Seven new drimane-type sesquiterpennoids,phellinuins A-G(1-7),together with one known compound 3b,11,12-trihydroxydrimene(8)were isolated from the cultures of mushroom Phellinus tuberculosus.Their structures were eluc...Seven new drimane-type sesquiterpennoids,phellinuins A-G(1-7),together with one known compound 3b,11,12-trihydroxydrimene(8)were isolated from the cultures of mushroom Phellinus tuberculosus.Their structures were elucidated on the basis of NMR and MS spectroscopic data and by comparison with data reported in the literature.展开更多
A novel chirality pairing recognition was found between D-and L-amino acid derivatives.Novel spiral alkaloids formed in the recognition reaction.Possible mechanism was proposed for the stereoselective and chemoselecti...A novel chirality pairing recognition was found between D-and L-amino acid derivatives.Novel spiral alkaloids formed in the recognition reaction.Possible mechanism was proposed for the stereoselective and chemoselective reactions.展开更多
Marine-derived fungi are well known as rich sources of bioactive natural products.Growing evidences indicated that indole alkaloids,isolated from a variety of marine-derived fungi,have attracted considerable attention...Marine-derived fungi are well known as rich sources of bioactive natural products.Growing evidences indicated that indole alkaloids,isolated from a variety of marine-derived fungi,have attracted considerable attention for their diverse,challenging structural complexity and promising bioactivities,and therefore,indole alkaloids have potential to be pharmaceutical lead compounds.Systemic compilation of the relevant literature.In this review,we demonstrated a comprehensive overview of 431 new indole alkaloids from 21 genera of marine-derived fungi with an emphasis on their structures and bioactivities,covering literatures published during 1982–2019.展开更多
基金financially supported by National Natural Sciences Foundation of China(U1132607)Youth Innovation Promotion Association,CAS(2011312D11019).
文摘Seven new drimane-type sesquiterpennoids,phellinuins A-G(1-7),together with one known compound 3b,11,12-trihydroxydrimene(8)were isolated from the cultures of mushroom Phellinus tuberculosus.Their structures were elucidated on the basis of NMR and MS spectroscopic data and by comparison with data reported in the literature.
基金supports from NSFC(30873141)973 Program(2009CB522300)Hebei University and the State Key Laboratory of Phytochemistry and Plant Resources in West China.
文摘A novel chirality pairing recognition was found between D-and L-amino acid derivatives.Novel spiral alkaloids formed in the recognition reaction.Possible mechanism was proposed for the stereoselective and chemoselective reactions.
基金This work was supported by the National Natural Science Foundation of China(Nos.41606174,21877025)the Scientific Research Foundation of Hebei educational committee(No.BJ2020048)+1 种基金the China Postdoctoral Science Foundation(No.2019M661045)the Natural Science Interdisciplinary Research Program of Hebei University(No.DXK201913).
文摘Marine-derived fungi are well known as rich sources of bioactive natural products.Growing evidences indicated that indole alkaloids,isolated from a variety of marine-derived fungi,have attracted considerable attention for their diverse,challenging structural complexity and promising bioactivities,and therefore,indole alkaloids have potential to be pharmaceutical lead compounds.Systemic compilation of the relevant literature.In this review,we demonstrated a comprehensive overview of 431 new indole alkaloids from 21 genera of marine-derived fungi with an emphasis on their structures and bioactivities,covering literatures published during 1982–2019.
