Mobile Edge Computing(MEC)is a technology for the fifth-generation(5G)wireless communications to enable User Equipment(UE)to offload tasks to servers deployed at the edge of network.However,taking both delay and energ...Mobile Edge Computing(MEC)is a technology for the fifth-generation(5G)wireless communications to enable User Equipment(UE)to offload tasks to servers deployed at the edge of network.However,taking both delay and energy consumption into consideration in the 5G MEC system is usually complex and contradictory.Non-orthogonal multiple access(NOMA)enable more UEs to offload their computing tasks to MEC servers using the same spectrum resources to enhance the spectrum efficiency for 5G,which makes the problem even more complex in the NOMA-MEC system.In this work,a system utility maximization model is present to NOMA-MEC system,and two optimization algorithms based on Newton method and greedy algorithm respectively are proposed to jointly optimize the computing resource allocation,SIC order,transmission time slot allocation,which can easily achieve a better trade-off between the delay and energy consumption.The simulation results prove that the proposed method is effective for NOMA-MEC systems.展开更多
10-（4-Formylphenyl）-5,15-bis（pentafluorophenyl）corrole 1 and its gallium complex 1-Ga were used to investigate their photocytotoxicity in liver cancer （BEL-7402）, lung cancer （A549） and cervical cancer （Siha,...10-（4-Formylphenyl）-5,15-bis（pentafluorophenyl）corrole 1 and its gallium complex 1-Ga were used to investigate their photocytotoxicity in liver cancer （BEL-7402）, lung cancer （A549） and cervical cancer （Siha, Hela） cell lines. Among all the tested tumor cells, Siha tumor cells were the most sensitive to photodynamic therapy （PDT） treatment by 1 and 1-Ga. PDT IC50 of 1 and 1-Ga toward Siha tumor cell reaches 1.3 and 0.8 gmol/L respectively, which is 10-fold higher than that of cisplatin. 1 and 1-Ga might pass across the tumor cell membrane smoothly without the help of carrier protein, and mainly localized in the cytoplasm of tumor cell. After PDT treatment, the intracellular reactive oxygen species （ROS） level increased and the mitochondrial membrane potential decreased significantly, which would finally result in the apoptosis of tumor cells.展开更多
文摘Mobile Edge Computing(MEC)is a technology for the fifth-generation(5G)wireless communications to enable User Equipment(UE)to offload tasks to servers deployed at the edge of network.However,taking both delay and energy consumption into consideration in the 5G MEC system is usually complex and contradictory.Non-orthogonal multiple access(NOMA)enable more UEs to offload their computing tasks to MEC servers using the same spectrum resources to enhance the spectrum efficiency for 5G,which makes the problem even more complex in the NOMA-MEC system.In this work,a system utility maximization model is present to NOMA-MEC system,and two optimization algorithms based on Newton method and greedy algorithm respectively are proposed to jointly optimize the computing resource allocation,SIC order,transmission time slot allocation,which can easily achieve a better trade-off between the delay and energy consumption.The simulation results prove that the proposed method is effective for NOMA-MEC systems.
基金This work was supported by National Natural Sci-ence Foundation of China （NNSFC） under Grant （Nos., 21371059, 21671068）, the National Science Foundation of Guangdong Province （No. 2016A030313728）, the Open Fund of State Key Laboratory of Optoelectronic Materials and Technologies （Sun Yat-sen University） （No. OEMT-2015-KF-05）.
文摘10-（4-Formylphenyl）-5,15-bis（pentafluorophenyl）corrole 1 and its gallium complex 1-Ga were used to investigate their photocytotoxicity in liver cancer （BEL-7402）, lung cancer （A549） and cervical cancer （Siha, Hela） cell lines. Among all the tested tumor cells, Siha tumor cells were the most sensitive to photodynamic therapy （PDT） treatment by 1 and 1-Ga. PDT IC50 of 1 and 1-Ga toward Siha tumor cell reaches 1.3 and 0.8 gmol/L respectively, which is 10-fold higher than that of cisplatin. 1 and 1-Ga might pass across the tumor cell membrane smoothly without the help of carrier protein, and mainly localized in the cytoplasm of tumor cell. After PDT treatment, the intracellular reactive oxygen species （ROS） level increased and the mitochondrial membrane potential decreased significantly, which would finally result in the apoptosis of tumor cells.
