Recently, we have analyzed expressional transcriptome and proteome for a number of cancer cell lines, including 8 hepatocellular carcinoma (HCC) ones [1,2]. These 8 HCC cell lines consist of 6 metastatic (all with ...Recently, we have analyzed expressional transcriptome and proteome for a number of cancer cell lines, including 8 hepatocellular carcinoma (HCC) ones [1,2]. These 8 HCC cell lines consist of 6 metastatic (all with mutant p53) and 2 non-metastatic (with a mutant and a lost p53) ones, being all HBV traceable for relatively close genetic-backgrounds. We have analyzed the related dataset and obtained transcrip- tome (16353 genes) and proteome (7861 proteins) of these 8 HCC cell lines, and explored a group of up-regulated and down-regulated genes [3].展开更多
基金the International S&T Cooperation Program of China (2014DFB30020)the National Basic Research Program of China (2013CB910502, 2011CB910600)+1 种基金the National High Technology Research and Development Program of China(2012AA020200)the National Science and Technology Major Project (2012ZX1002012)
文摘Recently, we have analyzed expressional transcriptome and proteome for a number of cancer cell lines, including 8 hepatocellular carcinoma (HCC) ones [1,2]. These 8 HCC cell lines consist of 6 metastatic (all with mutant p53) and 2 non-metastatic (with a mutant and a lost p53) ones, being all HBV traceable for relatively close genetic-backgrounds. We have analyzed the related dataset and obtained transcrip- tome (16353 genes) and proteome (7861 proteins) of these 8 HCC cell lines, and explored a group of up-regulated and down-regulated genes [3].