The concept of adaptive radiotherapy(ART) was proposed 20 years ago, and since then a variety of methodologies and techniques have been developed to accommodate different clinical requirements, including both online a...The concept of adaptive radiotherapy(ART) was proposed 20 years ago, and since then a variety of methodologies and techniques have been developed to accommodate different clinical requirements, including both online and offline plan adaptations. Compared with pre-treatment planning, plan adaptation involves more computational tasks and consequently has increased complexity and computational burden. While ART can benefit many cancer patients, challenges still exist in development and implementation of high-quality ART programs. In this short review, we will focus on the development of offline ART for lung cancer. We will also discuss the advantages and disadvantages of different clinical implementations of ART.展开更多
文摘The concept of adaptive radiotherapy(ART) was proposed 20 years ago, and since then a variety of methodologies and techniques have been developed to accommodate different clinical requirements, including both online and offline plan adaptations. Compared with pre-treatment planning, plan adaptation involves more computational tasks and consequently has increased complexity and computational burden. While ART can benefit many cancer patients, challenges still exist in development and implementation of high-quality ART programs. In this short review, we will focus on the development of offline ART for lung cancer. We will also discuss the advantages and disadvantages of different clinical implementations of ART.
