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内镜切除术与腹腔镜切除术治疗非微小胃间质瘤的对比研究 被引量:6
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作者 何斌 范卫东 +1 位作者 邹欢 严苏 《中国内镜杂志》 2021年第12期39-44,共6页
目的对比分析内镜下切除和腹腔镜手术切除非微小胃间质瘤(直径大于1 cm且小于5 cm)的疗效及安全性。方法回顾性分析2012年1月-2017年12月在苏州大学附属第一医院和苏州大学附属张家港医院行内镜下切除和外科腹腔镜手术治疗、并经术后病... 目的对比分析内镜下切除和腹腔镜手术切除非微小胃间质瘤(直径大于1 cm且小于5 cm)的疗效及安全性。方法回顾性分析2012年1月-2017年12月在苏州大学附属第一医院和苏州大学附属张家港医院行内镜下切除和外科腹腔镜手术治疗、并经术后病理及免疫组化确诊为非微小胃间质瘤患者的临床资料。根据手术方式将患者分为内镜切除组和腹腔镜手术组,比较两组患者术后住院时间、并发症、治愈性切除率等。结果内镜切除组术后进食时间、术后排气时间、住院时间较腹腔镜手术组短,住院费用较腹腔镜手术组少,两组患者比较,差异有统计学意义(均P<0.05)。术后对所有患者进行随访,内镜切除组平均随访时间为32个月,有1例出现复发;腹腔镜手术组平均随访时间为35个月,有1例出现复发,1例出现转移,两组患者比较,差异无统计学意义(P>0.05)。结论内镜下切除直径大于1 cm且小于5 cm的非微小胃间质瘤,具有肿瘤切除率高、术后恢复快、并发症少等优势,且与腹腔镜手术相比,复发率无明显差异。 展开更多
关键词 胃间质瘤 内镜切除术 腹腔镜手术 安全性 疗效
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Clinical features of ankylosing spondylitis associated with acute anterior uveitis in Chinese patients 被引量:5
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作者 Shu-Xing Ji, huan zou 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2012年第2期164-166,共3页
AIM: To characterize the clinical features, diagnosis, treatment and prognosis of uveitis associated with ankylosing spondylitis (AS) in Chinese patients. METHODS: Two hundred and three patients with uveitis associate... AIM: To characterize the clinical features, diagnosis, treatment and prognosis of uveitis associated with ankylosing spondylitis (AS) in Chinese patients. METHODS: Two hundred and three patients with uveitis associated with AS followed-up in the Third Military Medical University Daping Hospital between 2005 and 2010 were retrospectively evaluated in this study. Complete ophthalmological examinations were evaluated at baseline and during the follow-up period. The gender, age, follow-up time, mean frequency of uveitis onset, and accompanying eye examination findings, history, demographical parameters were reviewed. All the patients presented complete clinical and radiologic (sacroiliac, lumbar, dorsal and cervical spine, knee, ankle, shoulder, hip, elbow) evaluation. HLA-B27 typing was also searched. RESULTS: There were 203 patients diagnosed with AS associated welt's. All showed sacroiliac X-ray changes indicative of AS. There were 184 male and 19 female patients. The average age of patients was 35 +/- 12 (range 18-50). Mean follow-up period was 2.4 years (1-5 years). Acute anterior wets was the most common type of uveitis in both genders. 121 eyes presented unilateral involvement (55.2%), and 92 eyes presented bilateral involvement (45.3%) with onset alternately. 22 eyes occurred hypopyon, 16 eyes were found anterior vitreous cells, 7 eyes were noted reactive macular edema or exudation, 29 eyes presented posterior synechiae of iris, and 14 eyes presented cataract, 9 eyes presented secondary glaucoma, 2 eyes presented bend corneal degeneration and 1 eyes presented atrophy of eyeball. At the final visit, uveitis was well controlled in most patients. CONCLUSION: AS associated with uveitis in Chinese patients mainly manifests as acute anterior uveitis. A combination of corticosteroids with other mydriasis agents is effective for most AS associated with uveitis patients. In general, the prognosis is good in these cases. 展开更多
关键词 HLA-B27 anterior uveitis acute anterior uveitis ankylosing spondylitis associated uveitis HLA-B27 associated uveitis
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Moderating effect of psychological resilience on the perceived social support and loneliness in the left-behind elderly in rural areas
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作者 Yue Liu Lin huang +3 位作者 Qin Liu Gui-Zhen Qian huan zou Shan Zhang 《Frontiers of Nursing》 2021年第4期357-363,共7页
Objective:To investigate the loneliness and psychological resilience with the perceived social support of the left-behind elderly in rural areas and explore the moderating effect of psychological resilience on the und... Objective:To investigate the loneliness and psychological resilience with the perceived social support of the left-behind elderly in rural areas and explore the moderating effect of psychological resilience on the understanding of social support and loneliness of the left-behind elderly in rural areas.Methods:A cross-sectional study was conducted;272 left-behind elderly people in 6 rural villages in the Sichuan Province were investigated by using the General Situation Questionnaire,Perceived Social Support Scale(PSSS),Connor-Davidson Resilience Scale(CD-RISC),and the University of California at Los Angeles Loneliness Scale(UCLA)with a stratified random cluster sampling method.Results:The loneliness score of the left-behind elderly in rural areas was 52.54±7.25,the psychological resilience score was 78(68.87),and the perceived social support score was 57(51.62).The perceived social support and psychological resilience were negatively correlated with loneliness,while the perceived social support was positively correlated with psychological resilience.The moderating effect of psychological resilience on the perceived social support and loneliness of the left-behind elderly in rural areas was−0.102(P<0.001).Conclusions:Higher level resilience is of positive significance to alleviate the negative effect of social support on loneliness.Improving the resilience of the left-behind elderly in rural areas is a beneficial exploration to promote their mental health. 展开更多
关键词 LONELINESS moderating effect perceived social support psychological resilience the left-behind elderly
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抗癫痫药物左乙拉西坦注射液和口服片剂在中国健康志愿者中的药动学、安全性和生物等效性研究(英文) 被引量:2
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作者 胡岚岚 周娟 +2 位作者 邹欢 张玥 汤建林 《Journal of Chinese Pharmaceutical Sciences》 CAS CSCD 2018年第11期777-786,共10页
左乙拉西坦(LEV)的静脉注射制剂在世界范围内的临床应用已有多年,但在中国还没有上市。在本研究中,我们旨在评估静脉和口服的抗癫痫药物左乙拉西坦在中国健康志愿者中的生物等效性。两个随机、单剂量(1500毫克)、开放、双周期、交叉试... 左乙拉西坦(LEV)的静脉注射制剂在世界范围内的临床应用已有多年,但在中国还没有上市。在本研究中,我们旨在评估静脉和口服的抗癫痫药物左乙拉西坦在中国健康志愿者中的生物等效性。两个随机、单剂量(1500毫克)、开放、双周期、交叉试验按照如下方式进行:A试验:入选健康男性受试者22例,静脉滴注15分钟,于口服给药和静脉滴注结束后进行血样的采集; B试验:入选健康男性和女性受试者24例,静脉滴注45分钟,于口服给药和静脉滴注开始后进行血样的采集。最后对左乙拉西坦静脉注射和口服两种制剂的AUC0-t(从0到最后可测血浆浓度的曲线下面积)、Cmax(最大血浆浓度)的几何均值比及安全性进行评价。结果显示,左乙拉西坦(1500mg)静脉滴注15分钟与口服片剂相比, AUC0-t和Cmax的90%置信区间未在80.00%~125.00%的接受范围之内,而静脉滴注45分钟的AUC0-t和Cmax与口服片剂相比显示等效。两次试验最常见的不良反应是嗜睡,在试验A中共有8例受试者发生了9次轻度不良反应,在试验B中共有19例受试者发生29次轻度不良反应。由于45分钟的静脉滴注试验证实了片剂和注射液的生物等效性,所以左乙拉西坦1500mg的静脉注射制剂(45分钟滴注)和口服制剂具有可替换性。 展开更多
关键词 左乙拉西坦 癫痫 静脉注射剂型 生物等效性 安全性和耐受性
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Preparation and Characterization of Flame Retardant and Low Smoke Releasing Oil-resistant EVA/NBR Blends 被引量:8
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作者 huan zou Jun Sun +3 位作者 Xiao-yu Gu Peng Jiang Xi-shan Liu 张胜 《Chinese Journal of Polymer Science》 SCIE CAS CSCD 2015年第4期554-563,共10页
Nano-SiO2 and/or MoO3 were introduced to ethylene-vinyl acetate/nitrile butadiene rubber (EVA/NBR) blends containing magnesium hydroxide (MH) and red phosphorus (RP) to further improve the mechanical properties,... Nano-SiO2 and/or MoO3 were introduced to ethylene-vinyl acetate/nitrile butadiene rubber (EVA/NBR) blends containing magnesium hydroxide (MH) and red phosphorus (RP) to further improve the mechanical properties, oil resistance, smoke suppression and flame retardancy. The results indicated that the tensile strength and oil resistance were significantly improved by incorporating nano-SiO2. Smoke suppression tests for EVA/NBR blend samples showed that both nano-SiO2 and MoO3 can significantly reduce smoke release amount. The flammability characterization indicated that the blended sample with an LOI value of 33.0 could achieve V-0 level in the UL-94 test. Cone calorimetry test data showed the peak heat release rate was 67% lower than that for pure EVA/NBR. Thermal analysis showed that the presence of both nano-SiO2 and MoO3 was beneficial to promoting char formation of the EVA/NBR blends. Char residual analysis suggested that MoO3 aggregated in solid phase during combustion. 展开更多
关键词 Ethylene-vinyl acetate/nitrile butadiene rubber Tensile properties Oil resistance Smoke suppression Flame retardancy.
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Advancing index-based climate risk assessment to facilitate adaptation planning:Application in Shanghai and Shenzhen,China
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作者 Zhan TIAN Xin-Yang LYU +6 位作者 huan zou Hong-Long YANG Laixiang SUN Maria Sunyer PINYA Qing-Chen CHAO Ai-Qing FENG Ben SMITH 《Advances in Climate Change Research》 SCIE CSCD 2022年第3期432-442,共11页
One of the key issues in climate risk management is to develop climate resilient infrastructure so as to ensure safety and sustainability of urban functioning systems as well as mitigate the adverse impacts associated... One of the key issues in climate risk management is to develop climate resilient infrastructure so as to ensure safety and sustainability of urban functioning systems as well as mitigate the adverse impacts associated with increasing climate hazards.However,conventional methods of assessing risks do not fully address the interaction of various subsystems within the city system and are unable to consolidate diverse opinions of various stakeholders on their assessments of sector-specific risks posed by climate change.To address this gap,this study advances an integrated-systems-analysis tool-Climate Risk Assessment of Infrastructure Tool(CRAIT),and applies it to analyze and compare the extent of risk factor exposure and vulnerability over time across five critical urban infrastructure sectors in Shanghai and Shenzhen,two cities that have distinctive geo-climate profiles and histories of infrastructure development.The results show significantly higher level of variation between the two cities in terms of vulnerability levels than that of exposure.More specifically,the sectors of critical buildings,water,energy,and information&communication in Shenzhen have significantly higher vulnerability levels than Shanghai in both the 2000s and the 2050s.We further discussed the vulnerability levels of subsystems in each sector and proposed twelve potential adaptation options for the roads system based on four sets of criteria:technical feasibility,flexibility,co-benefits,and policy compatibility.The application of CRAIT is bound to be a knowledge co-production process with the local experts and stakeholders.This knowledge co-production process highlights the importance of management advancements and nature-based green solutions in managing climate change risk in the future though differences are observed across the efficacy categories due to the geographical and meteorological conditions in the two cities.This study demonstrates that this knowledge co-creation process is valuable in facilitating policymakers'decision-making and their feedback to scientific understanding in climate risk assessment,and that this approach has general applicability for cities in other regions and countries. 展开更多
关键词 Climate risk assessment MEGACITIES Resilient urban infrastructures SUBSYSTEM Knowledge co-creation process China
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