背景:生物医学领域碳纳米材料的研究蓬勃发展,相关科研成果逐年增加,但此领域的年发文量、国家、机构、作者的研究情况及研究热点与趋势等内容的可视化分析相对匮乏。目的:展现生物医学领域碳纳米材料研究现状,揭示主要的研究主体,探索...背景:生物医学领域碳纳米材料的研究蓬勃发展,相关科研成果逐年增加,但此领域的年发文量、国家、机构、作者的研究情况及研究热点与趋势等内容的可视化分析相对匮乏。目的:展现生物医学领域碳纳米材料研究现状,揭示主要的研究主体,探索研究热点及发展趋势,为此领域未来发展提供参考。方法:以Web of Science核心集数据库为文献来源,检索2012-2023年生物医学领域碳纳米材料的相关文献,运用Citespace软件以国家、机构、作者、关键词、共被引为节点生成知识图谱并进行可视化分析。结果与结论:①共纳入2932篇文献,碳纳米材料在医学领域年发文量多且增长速度较快;美国发文量较多;中国是该领域的新兴力量,发文量虽然最多,但研究水平和影响力还有待提高;中国科学院是最大的合作网络机构,主要以国内机构为合作对象,缺少与国外知名单位的合作。②关键词分析显示,碳点的绿色合成方式及应用是近年来的研究热点;其次碳纳米材料与癌症光疗、免疫疗法相结合的新方法是未来研究中的重点方向。③共被引动态发展趋势提示,组织工程是生物医学领域碳纳米材料的热点研究主题,主要包括碳纳米材料对于心脏和神经组织修复和再生的研究以及作为3D和4D生物打印的生物墨水添加剂。④未来随着生物医学领域朝着以治疗为中心的精准方向发展,科研人员应加快创建科学有效的碳纳米材料与科技、新型聚合物或有机分子及新治疗方法等结合形成的碳基体系,发挥碳纳米材料的最大效应。展开更多
This study aims to investigate the correlation between the permeation effect and microfabric of the slip zone soils with Huangtupo landslide in the Three Gorges Reservoir as the study case. Based on the permeability t...This study aims to investigate the correlation between the permeation effect and microfabric of the slip zone soils with Huangtupo landslide in the Three Gorges Reservoir as the study case. Based on the permeability test and scanning electron microscope(SEM) images analysis, the fractal theory and probability entropy are used to quantify the characteristics of the remodeling specimens. First, the relationships between initial moisture content(IMC) and microstructure of the soil(percentage of particle area(PPA), pore roundness(Rp)) before and after permeability test are summarized. Then, the fractal dimension of the soil(pore distribution(Dpd), pore size(Dps)) are analyzed under the permeation effect. Based on the probability entropy, the entropy of pore(Ep) is used to characterize the porosity orientation, and the rose diagrams are used to show the particle orientation under the permeation effect. Finally, the relationship between the microstructure of the soil and its mechanical property is discussed. Results show that under the permeation effect, the microstructure of the soil has undergone tremendous changes. A flat long pore channel is formed. The order of the pore arrangement is enhanced, and soil particles switch the long axis to parallel infiltration direction to reach a new steady state. It can be inferred that the strength of soil would be weakened if the fractal dimension of soil pore decreases under any external environment.展开更多
文摘背景:生物医学领域碳纳米材料的研究蓬勃发展,相关科研成果逐年增加,但此领域的年发文量、国家、机构、作者的研究情况及研究热点与趋势等内容的可视化分析相对匮乏。目的:展现生物医学领域碳纳米材料研究现状,揭示主要的研究主体,探索研究热点及发展趋势,为此领域未来发展提供参考。方法:以Web of Science核心集数据库为文献来源,检索2012-2023年生物医学领域碳纳米材料的相关文献,运用Citespace软件以国家、机构、作者、关键词、共被引为节点生成知识图谱并进行可视化分析。结果与结论:①共纳入2932篇文献,碳纳米材料在医学领域年发文量多且增长速度较快;美国发文量较多;中国是该领域的新兴力量,发文量虽然最多,但研究水平和影响力还有待提高;中国科学院是最大的合作网络机构,主要以国内机构为合作对象,缺少与国外知名单位的合作。②关键词分析显示,碳点的绿色合成方式及应用是近年来的研究热点;其次碳纳米材料与癌症光疗、免疫疗法相结合的新方法是未来研究中的重点方向。③共被引动态发展趋势提示,组织工程是生物医学领域碳纳米材料的热点研究主题,主要包括碳纳米材料对于心脏和神经组织修复和再生的研究以及作为3D和4D生物打印的生物墨水添加剂。④未来随着生物医学领域朝着以治疗为中心的精准方向发展,科研人员应加快创建科学有效的碳纳米材料与科技、新型聚合物或有机分子及新治疗方法等结合形成的碳基体系,发挥碳纳米材料的最大效应。
基金supported by the National Key R&D Program of China (2017YFC1501301)the National Natural Science Foundation of China (No. 41572278 and No. 41772310)
文摘This study aims to investigate the correlation between the permeation effect and microfabric of the slip zone soils with Huangtupo landslide in the Three Gorges Reservoir as the study case. Based on the permeability test and scanning electron microscope(SEM) images analysis, the fractal theory and probability entropy are used to quantify the characteristics of the remodeling specimens. First, the relationships between initial moisture content(IMC) and microstructure of the soil(percentage of particle area(PPA), pore roundness(Rp)) before and after permeability test are summarized. Then, the fractal dimension of the soil(pore distribution(Dpd), pore size(Dps)) are analyzed under the permeation effect. Based on the probability entropy, the entropy of pore(Ep) is used to characterize the porosity orientation, and the rose diagrams are used to show the particle orientation under the permeation effect. Finally, the relationship between the microstructure of the soil and its mechanical property is discussed. Results show that under the permeation effect, the microstructure of the soil has undergone tremendous changes. A flat long pore channel is formed. The order of the pore arrangement is enhanced, and soil particles switch the long axis to parallel infiltration direction to reach a new steady state. It can be inferred that the strength of soil would be weakened if the fractal dimension of soil pore decreases under any external environment.