目的分析基于从头训练模式深度学习-卷积神经网络模型[the deep learning convolutional neural network model trained from scratch,DL-CNN(fs)]的人工智能算法评估急性肺动脉血栓栓塞(acute pulmonary thromboembolism,APE)的价值。...目的分析基于从头训练模式深度学习-卷积神经网络模型[the deep learning convolutional neural network model trained from scratch,DL-CNN(fs)]的人工智能算法评估急性肺动脉血栓栓塞(acute pulmonary thromboembolism,APE)的价值。方法回顾性纳入214例可疑APE行CT肺动脉造影(CTPA)的住院患者,包括急性肺动脉血栓栓塞137例,阴性77例。放射科医师根据CTPA图像判断有无APE,并计算Qanadli评分、Mastora评分和其他CTPA参数。采用DL-CNN(fs)训练网络模型自动检测栓子的分布及容积。评估DL-CNN(fs)模型测量血栓分布的价值,计算血栓负荷与Qanadli评分、Mastora评分和其他CTPA参数的相关性。结果DL-CNN(fs)测算的中心肺动脉栓子敏感度、特异度、感兴趣区曲线下面积(AUC)分别为100%、16.8%、0.584(95%CI,0.508~0.661);DL-CNN(fs)测算的外周肺动脉栓子敏感度、特异度、AUC均较高(R1-R9,60.8%~95.2%,67.9%~87.1%,0.740~0.844;L1-L10,64.6%~93.4%,62.7%~83.1%,0.732~0.791)。DL-CNN(fs)测算的栓子体积与Qanadli score肺栓塞指数显著正相关(r=0.867,P<0.001),与Mastora score肺栓塞指数显著正相关(r=0.854,P<0.001),与右心室及左心室最大横径比、右心室及左心室最大面积比呈正相关(r=0.549,0.559,P<0.01)。结论DL-CNN(fs)模型检测外周肺动脉栓子具有较高的价值,对中心肺动脉栓子诊断特异度有待进一步提高。DL-CNN(fs)模型自动提供APE患者的栓子体积,可以一定程度反映栓塞程度及右心功能,能够辅助医生对于APE患者血栓负荷及危险分层的快速评估。展开更多
A group of A-Kr dating data of volcanic rocks in Taiwan Island is listed in thes paper, which clarifies the data of volcanic activity. And according to changes of plate movement in East Asia, a basic regularity of the...A group of A-Kr dating data of volcanic rocks in Taiwan Island is listed in thes paper, which clarifies the data of volcanic activity. And according to changes of plate movement in East Asia, a basic regularity of the volcanic activity in Taiwan can be obtainted, i.e. it is closely related with plate movement. The volcanic activity in Taiwan has always been moving about since Mesozoic, as the island lies in a special place of plate tectonic in East Asia, and the volcanic activity zone has changed with variations of plate motion. The paleo-Pacific plate launched a subduction toward the west in Cretaceous. Kula plate took a subduction toward the north from Cretaceous to Eogene. In Oligocene, the direction of the subduction of the Pacific plate changed from northward to westward. Taiwan Island has been the first to be affected by this change since Miocene Epoch. Therefore, volcanic activity occurs in the middle and the east of Taiwan Island. In addition, as the border of subduction moved eastward, the volcanic activity zone moves toward the east, too.Penglai movement in the period ranging from Tertiary to Quatemary is the most magnificent transformation in geological history of Taiwan. As the subduction movement of the Philippine Sea plate was replaced by the collision with Taiwan crust, the volcanic activity in the east of Taiwan Island ceased. Only the northem island and some offshore islands constitute a part of the Quatemary volcanic arc where the signs of volcanic activiy has been still displayed by now. However, the volcanic activity of the Penghu Island Group fell into the same category as that in Quatemary which was caused by the fracture activations in the eastem coast of China.展开更多
文摘目的分析基于从头训练模式深度学习-卷积神经网络模型[the deep learning convolutional neural network model trained from scratch,DL-CNN(fs)]的人工智能算法评估急性肺动脉血栓栓塞(acute pulmonary thromboembolism,APE)的价值。方法回顾性纳入214例可疑APE行CT肺动脉造影(CTPA)的住院患者,包括急性肺动脉血栓栓塞137例,阴性77例。放射科医师根据CTPA图像判断有无APE,并计算Qanadli评分、Mastora评分和其他CTPA参数。采用DL-CNN(fs)训练网络模型自动检测栓子的分布及容积。评估DL-CNN(fs)模型测量血栓分布的价值,计算血栓负荷与Qanadli评分、Mastora评分和其他CTPA参数的相关性。结果DL-CNN(fs)测算的中心肺动脉栓子敏感度、特异度、感兴趣区曲线下面积(AUC)分别为100%、16.8%、0.584(95%CI,0.508~0.661);DL-CNN(fs)测算的外周肺动脉栓子敏感度、特异度、AUC均较高(R1-R9,60.8%~95.2%,67.9%~87.1%,0.740~0.844;L1-L10,64.6%~93.4%,62.7%~83.1%,0.732~0.791)。DL-CNN(fs)测算的栓子体积与Qanadli score肺栓塞指数显著正相关(r=0.867,P<0.001),与Mastora score肺栓塞指数显著正相关(r=0.854,P<0.001),与右心室及左心室最大横径比、右心室及左心室最大面积比呈正相关(r=0.549,0.559,P<0.01)。结论DL-CNN(fs)模型检测外周肺动脉栓子具有较高的价值,对中心肺动脉栓子诊断特异度有待进一步提高。DL-CNN(fs)模型自动提供APE患者的栓子体积,可以一定程度反映栓塞程度及右心功能,能够辅助医生对于APE患者血栓负荷及危险分层的快速评估。
文摘A group of A-Kr dating data of volcanic rocks in Taiwan Island is listed in thes paper, which clarifies the data of volcanic activity. And according to changes of plate movement in East Asia, a basic regularity of the volcanic activity in Taiwan can be obtainted, i.e. it is closely related with plate movement. The volcanic activity in Taiwan has always been moving about since Mesozoic, as the island lies in a special place of plate tectonic in East Asia, and the volcanic activity zone has changed with variations of plate motion. The paleo-Pacific plate launched a subduction toward the west in Cretaceous. Kula plate took a subduction toward the north from Cretaceous to Eogene. In Oligocene, the direction of the subduction of the Pacific plate changed from northward to westward. Taiwan Island has been the first to be affected by this change since Miocene Epoch. Therefore, volcanic activity occurs in the middle and the east of Taiwan Island. In addition, as the border of subduction moved eastward, the volcanic activity zone moves toward the east, too.Penglai movement in the period ranging from Tertiary to Quatemary is the most magnificent transformation in geological history of Taiwan. As the subduction movement of the Philippine Sea plate was replaced by the collision with Taiwan crust, the volcanic activity in the east of Taiwan Island ceased. Only the northem island and some offshore islands constitute a part of the Quatemary volcanic arc where the signs of volcanic activiy has been still displayed by now. However, the volcanic activity of the Penghu Island Group fell into the same category as that in Quatemary which was caused by the fracture activations in the eastem coast of China.
