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皮肌炎继发肺部星形奴卡菌感染
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作者 易清玲 唐洁 +3 位作者 宋君 黄忠奎 罗军 何沅莉 《临床皮肤科杂志》 CAS CSCD 北大核心 2024年第4期224-227,共4页
报告1例皮肌炎继发肺部星形奴卡菌感染。患者女,46岁。因眶周、胸部及双上肢红斑伴四肢肌肉乏力4个月,声嘶、颈部及胸痛10余天入院。皮肤科检查:满月脸,眶周、胸部、双上肢和指关节背侧散在色素沉着斑,肌力Ⅲ~Ⅳ级。天门冬氨酸氨基转移... 报告1例皮肌炎继发肺部星形奴卡菌感染。患者女,46岁。因眶周、胸部及双上肢红斑伴四肢肌肉乏力4个月,声嘶、颈部及胸痛10余天入院。皮肤科检查:满月脸,眶周、胸部、双上肢和指关节背侧散在色素沉着斑,肌力Ⅲ~Ⅳ级。天门冬氨酸氨基转移酶、丙氨酸氨基转移酶、乳酸脱氢酶、肌酸激酶均升高。肌电图示肌源性损害活动期。胸部CT示右肺上叶尖段空洞软组织结节。右肺上叶穿刺组织细菌培养可见星形奴卡菌。诊断:皮肌炎继发肺部星形奴卡菌感染。停用免疫抑制剂后,予复方磺胺甲唑、泼尼松及羟氯喹等治疗。 展开更多
关键词 皮肌炎 星形奴卡菌 肺部
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阿维A与环孢素A联合311nm窄谱紫外线治疗重度银屑病的疗效 被引量:1
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作者 唐帮丽 黄忠奎 +2 位作者 丁钰 易清玲 刘渝鹏 《世界中医药》 CAS 2017年第A01期53-54,共2页
目的观察A与环孢素A联合311nm窄谱紫外线(NB-UVB)治疗重度银屑病的疗效及讨论其治疗机制。方法采用平行随机方法,对照组口服阿维A胶囊0.6mg/(kg·d),治疗组给予口服阿维A胶囊0.6mg/kg/d+环孢素A3mg/(kg·d),同时给予311nmNB-... 目的观察A与环孢素A联合311nm窄谱紫外线(NB-UVB)治疗重度银屑病的疗效及讨论其治疗机制。方法采用平行随机方法,对照组口服阿维A胶囊0.6mg/(kg·d),治疗组给予口服阿维A胶囊0.6mg/kg/d+环孢素A3mg/(kg·d),同时给予311nmNB-UVB治疗。于治疗前、治疗后6周、12周PASI评分,治疗前、治疗后6周、12周监测血清T细胞及肿瘤坏死因子(TNF-α)水平及实验室检查,并记录不良反应。结果治疗组在治疗后6周、12周PASI评分较对照组明显降低,治疗组治疗有效率明显高于对照组。2组血清TNF-α在治疗前后变化不明显。结论阿维A胶囊联合环孢素A对重度银屑病的疗效明显,但是否通过调节TNF-α达到疗效还不明确,需更多的临床资料进一步证实。 展开更多
关键词 阿维A 311nm窄谱紫外线 银屑病
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单发性肝转移瘤的CT与MRI特征分析 被引量:4
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作者 覃夏丽 黄仲奎 +4 位作者 陈钇地 谢雨恩 龙莉玲 高银娟 周春懿 《广西医科大学学报》 CAS 2020年第9期1677-1680,共4页
目的:探讨单发性肝转移瘤(IHM)的CT及MRI影像特征,以提高诊断及鉴别诊断能力。方法:回顾性收集广西医科大学第一附属医院2010年2月至2018年4月收治的IHM患者69例,65例患者CT平扫加增强检查,37例患者同时CT和MRI平扫加增强检查,41例行MR... 目的:探讨单发性肝转移瘤(IHM)的CT及MRI影像特征,以提高诊断及鉴别诊断能力。方法:回顾性收集广西医科大学第一附属医院2010年2月至2018年4月收治的IHM患者69例,65例患者CT平扫加增强检查,37例患者同时CT和MRI平扫加增强检查,41例行MRI平扫加增强检查,其中13例使用特殊对比剂检查。将病灶分为直径≤3 cm组(n=47)和直径>3 cm组(n=22),分析其临床特点及CT和MRI的强化特征等。结果:直径>3 cm组IHM在T2WI表现为不均匀高信号、DWI出现“反靶征”,与直径≤3 cm组IHM比较,差异均具有统计学意义(P<0.05);两组转移瘤的CT、MRI强化方式均有其特征性。13例IHM在肝胆期均表现为低信号,其中8例出现中央或边缘斑片状稍高信号。结论:IHM在CT和MRI表现上有其特征性,有助于诊断和鉴别诊断,可为临床提供重要的影像学信息。 展开更多
关键词 肝转移瘤 单发 CT 磁共振成像
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度普利尤单抗辅助治疗中重度特应性皮炎的疗效及对外周血Th1/Th2细胞的调控作用 被引量:4
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作者 唐帮丽 郑旭海 +4 位作者 黄忠奎 易清玲 丁钰 何沅莉 李燕 《中国美容医学》 CAS 2022年第12期77-80,共4页
目的:分析度普利尤单抗辅助治疗中重度特应性皮炎(Atopicdermatitis,AD)的疗效及对外周血Th1/Th2细胞的调控作用。方法:选择笔者科室2019年1月-2020年6月诊治的134例AD患者,采用计算机随机数字分组法分成对照组和治疗组,每组67例。对照... 目的:分析度普利尤单抗辅助治疗中重度特应性皮炎(Atopicdermatitis,AD)的疗效及对外周血Th1/Th2细胞的调控作用。方法:选择笔者科室2019年1月-2020年6月诊治的134例AD患者,采用计算机随机数字分组法分成对照组和治疗组,每组67例。对照组患者接受基础治疗,治疗组患者使用度普利尤单抗辅助治疗。治疗结束后评定两组患者外周血Th1/Th2比值,血清总IgE、血嗜酸性粒细胞(EOS)计数和皮损改善情况,以及湿疹面积和严重程度、临床疗效、疼痛及瘙痒情况和不良反应发生情况。结果:治疗前,两组患者外周血Th1/Th2比值,血清总IgE及EOS计数差异比较,差异均无统计学意义(P>0.05);治疗后,治疗组患者外周血Th1/Th2比值高于对照组(P<0.05),治疗组血清总IgE及EOS计数均低于对照组,差异均有统计学意义(P<0.05)。治疗前,两组皮损改善评分、EASI评分比较,差异均无统计学意义(P>0.05);治疗后,治疗组患者皮损改善评分、EASI评分均低于对照组,差异均有统计学意义(P<0.05),治疗组患者临床总有效率高于对照组(P<0.05)。治疗前两组患者疼痛及瘙痒评分差异比较无统计学意义(P>0.05),治疗后,治疗组患者疼痛及瘙痒评分均低于对照组(P<0.05),且治疗组患者不良反应发生率低于对照组,差异均有统计学意义(P<0.05)。结论:度普利尤单抗辅助治疗对中重度AD能提升患者临床疗效及免疫功能,建议临床推广应用。 展开更多
关键词 度普利尤单抗 中重度 特应性皮炎 皮损改善情况 外周血Th1、Th2 疗效
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4 - 10 Test Experimental Results for Laser Cooling of C3+ Ions at CSRe
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作者 Wang Hanbing Ma Xinwen +14 位作者 Wen W eiqiang huang zhongkui Zhang Dacheng Zhu Xiaolong Zhao Dongmei Li Jie Ma Xiaoming Yan Tailai Mao Ruishi Zhao Tiecheng Wu Junxia Yang Jiancheng Yuan Youjin Xia Jiawen Michael Bussmann 《IMP & HIRFL Annual Report》 2013年第1期186-187,共2页
关键词 英语 阅读 理解 物理研究
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4 - 9 Dielectronic Recombination Experiment of 78Kr28+ on HIRFL-CSRm
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作者 huang zhongkui Ma Xinwen +20 位作者 Wen Weiqiang Wang Hanbing Xu Weiqing Zhu Xiaolong Gao Yong Zhao Dongmei Cheng Xiaowei Yang Xiaodong Li jie Ma Xiaoming Yan Tailai Yang Jiancheng Mao Lijun Xia Jiawen Yuan Youjin Xu Hushan Xiao Guoqing Xu Xin ZhuLinfan ShiYinglong Dong Chenzhong 《IMP & HIRFL Annual Report》 2013年第1期185-186,共2页
关键词 英语 阅读 理解 物理研究
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4 - 5 Observation of Enhanced Schottky Signals of RF-bunched C3+ Ion Beam at the CSRe
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作者 Wen Weiqiang Ma Xinwen +14 位作者 Wang Hanbing huang zhongkui Zhang Dacheng Zhu Xiaolong Zhao Dongmei Li Jie Ma Xiaoming Yan Tailai Mao Ruishi Zhao Tiecheng Wu Junxia Yang Jiancheng Yuan Youjin Xia Jiawen Michael Bussmann 《IMP & HIRFL Annual Report》 2013年第1期181-181,共1页
关键词 英语 阅读 理解 物理研究
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4-6 Theoretical Study of Dielectronic Recombination of Li-Like 36Ar15+ Ions
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作者 Dou lijun Xie Luyou +2 位作者 huang zhongkui Dong Chenzhong Ma Xinwen 《IMP & HIRFL Annual Report》 2015年第1期200-200,共1页
Dielectronic recombination (DR) is an important electron–ion recombination process. This process is generallyconsidered to occur in two steps,e??+Aq+![A(q??1)+]![A(q??1)+]+nhv ; (1) where in the first step a free ... Dielectronic recombination (DR) is an important electron–ion recombination process. This process is generallyconsidered to occur in two steps,e??+Aq+![A(q??1)+]![A(q??1)+]+nhv ; (1) where in the first step a free electron is captured simultaneously with the excitation of a bound electron. In the second step the doubly-excited ion is stabilized by emitting photons. 展开更多
关键词 THEORETICAL Study DIELECTRONIC
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4-1 Dielectronic Recombination of 36Ar15+ and 112Sn34+ at the CSRm
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作者 huang zhongkui Ma Xinwen +19 位作者 Wen Weiqiang Wang Hanbing Chuai Xiaoya Dou Lijun Zhu Xiaolong Xu Xin Zhu Linfan Xu Weiqing Mao Lijun Li Jie Zhang Xiaohu Ma Xiaoming Yan Tailai Yang Jiancheng Yuan Youjin Xiao Guoqing Xia Jiawen Xie Luyou Dong Chenzhong DR collaboration 《IMP & HIRFL Annual Report》 2015年第1期195-195,共1页
The total recombination rate coefficients of lithium-like 36Ar15+ ions have been measured by employing the electron-ion merged-beams technique at the heavy ion storage ring CSRm at IMP[1]. Fig. 1 (a) shows the DR spec... The total recombination rate coefficients of lithium-like 36Ar15+ ions have been measured by employing the electron-ion merged-beams technique at the heavy ion storage ring CSRm at IMP[1]. Fig. 1 (a) shows the DR spectrum for electron energy from 0 to 35 eV in the center-of-mass (c.m.) frame involving all the DR resonances associated with 2s1=2!2p1=2 and 2s1=2!2p3=2 excitations. 展开更多
关键词 DIELECTRONIC Recombination 36Ar15+
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4-2 Lifetime and the Ratio of 12C3+ and 16O4+ at the CSRe
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作者 Wang Hanbing Ma Xinwen +14 位作者 Wen Weiqiang huang zhongkui Zhang Dacheng Hai Bang Chuai Xiaoya Zhao Dongmei Zhu Xiaolong Yang Jie Li Jie Mao Lijun Mao Ruishi Yang Jiancheng Yuan Youjin Zhao Hongwei Laser Cooling Collaboration 《IMP & HIRFL Annual Report》 2015年第1期196-196,共1页
Laser cooling is the most promising method to achieve high phase-space densities, even crystalline beams for relativistic heavy ion at storage rings[1]. A test laser cooling experiment has been performed with 12C3+ io... Laser cooling is the most promising method to achieve high phase-space densities, even crystalline beams for relativistic heavy ion at storage rings[1]. A test laser cooling experiment has been performed with 12C3+ ions at the CSRe. In this experiment, the 12C3+ ions were produced from an electron cyclotron resonance (ECR) ion source, and due to the residual gas and the injection gases such as CO and CO2, 16O4+ ions will be produced at the same time. 展开更多
关键词 12C3+ 16O4+ CSRe
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4-7 Isotope Shift in the Dielectronic Recombination of Highly-charged Ions
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作者 Chuai Xiaoya Ma Xinwen +2 位作者 Wen Weiqiang huang zhongkui Wang Hanbing 《IMP & HIRFL Annual Report》 2015年第1期201-201,共1页
Dielectronic recombination (DR) is a two-step resonance electron-ion collision process which can be utilized as a tool to measure precision spectroscopy for highly-charged ions (HCI). As a result, the isotope shift of... Dielectronic recombination (DR) is a two-step resonance electron-ion collision process which can be utilized as a tool to measure precision spectroscopy for highly-charged ions (HCI). As a result, the isotope shift of highly-charged ions can be measured by the DR technique and the nuclear properties such as the change in the mean-square charge radius can be extracted from the isotope shift[1]. 展开更多
关键词 Dielectroni Recombination Highly-charged
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4-8 Dielectronic Recombination of 112Sn35+ Ions at the CSRm
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作者 Xu Xin Wang Shuxing +15 位作者 Zhu Linfan huang zhongkui Ma Xinwen Wen Weiqiang Wang Hanbing Chuai Xiaoya Dou Lijun Zhu Xiaolong Zhao Dongmei Yuan Youjin Mao Lijun Li Jie Ma Xiaoming Yan Tailai Yang Jiancheng Xia Jiawen 《IMP & HIRFL Annual Report》 2015年第1期202-202,共1页
The total recombination rate coefficient of Phosphorus-like 112Sn35+ have been measured at the main cooler storage ring (CSRm) employing the electron-ion merged-beams technique. The Phosphorus-like 112Sn35+ ions were ... The total recombination rate coefficient of Phosphorus-like 112Sn35+ have been measured at the main cooler storage ring (CSRm) employing the electron-ion merged-beams technique. The Phosphorus-like 112Sn35+ ions were injected into the CSRm at an energy of 3.7 MeV/u with a typical current of 50 eA, and the momentum spread of the ion beam is 210?4 after several seconds of cooling. 展开更多
关键词 112Sn35+ IONS CSRM
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4-9 Progress of Laser Cooling of 12C3+ Ions at the CSRe
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作者 Wang Hanbing Wen Weiqiang +16 位作者 huang zhongkui Zhang Dacheng Hai Bang Zhu Xiaolong Li Jie Mao Lijun Mao Ruishi Yang Jiancheng Yuan Youjin Xia Jiawen Lewin Eidam Benjamin Rein Markus Loeser Zhu jiangfeng Danyal Winters Michael Bussmann Ma Xinwen 《IMP & HIRFL Annual Report》 2014年第1期187-187,共1页
Laser cooling is one of the most promising techniques to reach high phase-space densities and achieve phasetransition, ordered beam even crystalline beam for relativistic heavy ion beams at storage rings[1]. In order ... Laser cooling is one of the most promising techniques to reach high phase-space densities and achieve phasetransition, ordered beam even crystalline beam for relativistic heavy ion beams at storage rings[1]. In order torealize laser cooling at the CSRe in IMP, we performed a test experiment by using a pulsed laser system to coolthe relativistic 12C3+ ion beams on the CSRe in September 2014. Fig. 1 is the schematic view of the experimentalsetup. 展开更多
关键词 PROGRESS LASER COOLING
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4-5 Dielectronic Recombination of Li-like Argon Ions at the CSRm
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作者 huang zhongkui Ma Xinwen +13 位作者 Wen Weiqiang Wang Hanbing Chuai Xiaoya Zhu Xiaolong Zhao Dongmei Yuan Youjin Mao Lijun Li Jie Ma Xiaoming Yan Tailai Yang Jiancheng Xia Jiawen Xu Xin Zhu Linfan 《IMP & HIRFL Annual Report》 2014年第1期183-183,共1页
The main cooler storage ring (CSRm) equipped with an electron-cooler creates an ideal platform for dielectronicrecombination (DR) experiments. In order to fully understand our DR experimental setup and especially the ... The main cooler storage ring (CSRm) equipped with an electron-cooler creates an ideal platform for dielectronicrecombination (DR) experiments. In order to fully understand our DR experimental setup and especially the electronenergy detuning system, we have performed a DR calibration experiment using the Li-like argon ions at theCSRm. The Ar15+ has a simple electronic structure so the DR spectrum can be calculated with an ultra-highprecision and compared with the existing experimental data. The experiment was carried out at the relative energyfrom 0 to 32 eV that includes all DR resonances associated with 2s1=2 ! 2p1=2 and most of the 2s1=2 ! 2p3=2excitations. 展开更多
关键词 DIELECTRONIC Recombination ARGON
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4-8 Test Experiments of Laser Propagation and Control for Laser Cooling Experiment at the CSRe
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作者 Hai Bang Zhang Dacheng +3 位作者 Wang Hanbing Wen Weiqiang huang zhongkui Ma Xinwen 《IMP & HIRFL Annual Report》 2014年第1期186-186,共1页
Laser cooling of heavy ion beams is the most promising method to realize crystalline beams at storage rings[1].In order to perform the laser cooling experiment of C3+ at the CSRe[2], we tested the laser propagation an... Laser cooling of heavy ion beams is the most promising method to realize crystalline beams at storage rings[1].In order to perform the laser cooling experiment of C3+ at the CSRe[2], we tested the laser propagation and controlby using the He-Ne laser at the straight part (about 25 m long) before the experiment. The experimental resultsindicated that the laser was collimated and stable, and the laser intensity was strong enough after a long distancepropagation at the CSRe which satis ed the requirement of laser cooling of heavy ion beams. 展开更多
关键词 EXPERIMENTS LASER PROPAGATION
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4-6 Measurement of the Ratio of C3+ and O4+ Ions Produced by ECR Source to Prepare a Laser Cooling Experiment at Storage Rings
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作者 Zhu Xiaolong Wen Weiqiang +16 位作者 Ma Xinwen Li Jinyu Feng Wentian Zhang Ruitian Yan Shuncheng Guo Dalong Hai Bang Qian Dongbin Zhang Pengju Xu Shenyue Zhao Dongmei Yang Jie Zhang Dacheng Li Bin Gao Yong huang zhongkui Wang Hanbing 《IMP & HIRFL Annual Report》 2014年第1期184-184,共1页
The cooling of heavy ions can provide high-quality beams that are especially important for high-precisionexperimental nuclear and atomic physics. The laser cooling of relativistic C3+ ion beams at the experimental coo... The cooling of heavy ions can provide high-quality beams that are especially important for high-precisionexperimental nuclear and atomic physics. The laser cooling of relativistic C3+ ion beams at the experimental coolerstorage ring (CSRe) is being currently prepared at Institute of Modern Physics (IMP) in Lanzhou. An electroncyclotron resonance ion source (ECRIS) will be used to produce C3+ ion beams. Meanwhile, O4+ ions could alsobe produced due to residual gas because of the same mass-to-charge ratio. Therefore, both C3+ and O4+ ion beamswill be injected and circulate in a storage ring during the laser cooling experiment at the same time. A higher ratioof C3+ ions will lead to a better result for the laser cooling experiment. 展开更多
关键词 Measurement RATIO IONS
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Radiative Recombination Rates Enhancement at Low Energy Range in the Heavy Ion Storage Ring CSRm
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作者 Khan Nadir huang zhongkui +15 位作者 Wen Weiqiang Wang Shuxing Wang Hanbing Ma Wanlu Zhu Xiaolong Zhao Dongmei Zhu Linfan Mao Lijun Li Jie Ma Xiaoming Tang Meitang Yin Dayu Yang Weiqing Yang Jiancheng Yuan Youjin Ma Xinwen 《IMP & HIRFL Annual Report》 2019年第1期74-75,共2页
Recombination of Ar^(14+),Ar^(15+),Ca^(16+) and Ni^(19+) ions with electrons has been investigated at low energy range at the CSRm.For each ion,the absolute recombination rate coefficients have been measured with elec... Recombination of Ar^(14+),Ar^(15+),Ca^(16+) and Ni^(19+) ions with electrons has been investigated at low energy range at the CSRm.For each ion,the absolute recombination rate coefficients have been measured with electron-ion collision energies from 0 to 1000 meV which include the radiative recombination(RR)and also dielectronic recombination(DR)processes.In order to interpret the measured results. 展开更多
关键词 processes. ABSOLUTE COLLISION
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Dielectronic Recombination of F-like Ni^(25+) at the CSRm
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作者 Wang Shuxing huang zhongkui +14 位作者 Wen Weiqiang Wang Hanbing Nadir Khan Zhao Dongmei Zhu Xiaolong Mao Lijun Li Jie Ma Xiaoming Yin Dayu Mao Ruishi Yuan Youjin Yang Jiancheng Chen Chongyang Ma Xinwen Zhu Linfan 《IMP & HIRFL Annual Report》 2019年第1期73-73,共1页
The absolute rate cofficients for dielectronic recombination(DR)of F-like Ni^(19+) ions were measured by employing the electron-ion merged-beam technique at the heavy-ion storage ring CSRm.The measured DR spectrum cov... The absolute rate cofficients for dielectronic recombination(DR)of F-like Ni^(19+) ions were measured by employing the electron-ion merged-beam technique at the heavy-ion storage ring CSRm.The measured DR spectrum covers the energy range of 0~70 eV. 展开更多
关键词 ABSOLUTE SPECTRUM BEAM
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A Compact,Flexible Low Energy Experimental Platform of Highly Charged Ions for Atomic Physics Experimental Research
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作者 Zhu Xiaolong Ma Xinwen +17 位作者 Li Jinyu M.Schmidt Feng Wentian Peng Haibo Xu Jiawei G.Zschornack Liu Huiping Zhang Tongmin Zhao Dongmei Guo Dalong huang zhongkui Zhou Xianmin Gao Yong Cheng Rui Wang Hanbing Yang Jie Kang Long 《IMP & HIRFL Annual Report》 2019年第1期71-71,共1页
A new,compact and exible low energy experimental platform of highly charged ions(HCIs)based on an electron beam ion source of the Dresden EBIS-A type is presented.The so-called IMP EBIS-A Facility of the Institute of ... A new,compact and exible low energy experimental platform of highly charged ions(HCIs)based on an electron beam ion source of the Dresden EBIS-A type is presented.The so-called IMP EBIS-A Facility of the Institute of Modern Physics(IMP)in Lanzhou is designed as a user facility for the state-resolved charge exchange studies in HCIs with atoms and molecules collisions by cold target recoil ion momentum spectroscopy(COLTRIMS). 展开更多
关键词 HIGHLY MOMENTUM RESOLVED
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Dielectronic Recombination of Na-like Kr^(25+) at the CSRm
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作者 huang zhongkui Wen Weiqiang +15 位作者 Wang Shuxing Ma wanlu Wang Hanbing Nadir Khan Zhao Dongmei Zhu Xiaolong Mao Lijun Li Jie Ma Xiaoming Yin Dayu Mao Ruishi Yuan Youjin Yang Jiancheng Chen Chongyang Zhu Linfan Ma Xinwen 《IMP & HIRFL Annual Report》 2019年第1期72-72,共1页
The absolute rate coefficients for dielectronic recombination(DR)of Na-like Kr^(25+) ions were measured by employing the electron-ion merged-beam technique at the heavy-ion storage ring CSRm.The measured DR spectrum c... The absolute rate coefficients for dielectronic recombination(DR)of Na-like Kr^(25+) ions were measured by employing the electron-ion merged-beam technique at the heavy-ion storage ring CSRm.The measured DR spectrum covers the energy range of 0~70 eV. 展开更多
关键词 ABSOLUTE SPECTRUM BEAM
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