Molecular cytogenetic analyses of two new wheat-rye 6RL translocation lines with resistance to wheat powdery mildew

Rye(Secale cereale)is a valuable gene donor for wheat improvement,especially for its resistance to diseases.Developing rye-derived resistance sources is important for wheat breeding.In the present study,two wheat-rye derivatives,designated JS016 and JS110,were produced by crossing common wheat cultivar Yangmai 23 with Pakistani rye accession W2A.Using sequential genomic in situ hybridization(GISH)and multicolor fluorescence in situ hybridization(mc-FISH),JS016 and JS110 were identified as a T6BS.6RL translocation line and a T6BS.6BL6RL translocation line,respectively.Ten newly 6RL chromosome arm-specific markers were developed and used to confirm the 6RL translocation.The wheat 55K single-nucleotide polymorphism(SNP)array further verified the molecular cytogenetic identification results above and clarified their breakpoints at 430.9 and 523.0 Mb of chromosome 6B in JS016 and JS110,respectively.Resistance spectrum and allelism test demonstrated that JS016 and JS110 possessed novel powdery mildew resistance gene(s)that was derived from the 6RL translocation but differed from Pm20.Moreover,JS016 and JS110 had better agronomic traits than the previously reported 6RL translocation line carrying Pm20.To efficiently transfer and detect the 6RL translocation from JS016 and JS110,one 6RL-specific Kompetitive allele specific PCR(KASP)marker was developed and validated in high throughput marker-assisted selection(MAS).

Field-assisted conductive substrate sparks the redox kinetics of Co_(9)S_(8) in Li-and Na-ion batteries

As a promising candidate electrode material in both Li-and Na-ion batteries(L/SIBs),the application of Co_(9)S_(8) is being hindered by its unsatisfactory electrochemical performance caused by the sluggish ion diffusion kinetics and drastic volume expansion.Herein,a hybrid material composed of Co_(9)S_(8-x),N-doped carbon foam that seeded with Co nanoparticles(Co_(9)S_(8-x)@Co-NC) is constructed.Particularly,theoretical and experimental results imply that a built-in electric field at the interface of Co and NC is observed due to the variation of Fermi levels,forming rich Mott-Schottky-like heterointerfaces,which can significantly enhance the charge transfer capability between the active materials of Co_(9)S_(8) and conductive NC skeleton.Moreover,the sulfur defects in Co_(9)S_(8-x)can not only effectively lower the energy barrier of the ion diffusion and charge transfer processes,but also endow the target sample with more storage/adsorption/active sites for Li^(+)/Na^(+) ions,thus improving the rate performance of the Co_(9)S_(8-x)@Co-NC composite.As a result,the Co_(9)S_(8-x)@Co-NC exhibits fast surface-controlled redox kinetics and robust cycling stability.For instance,the Co_(9)S_(8-x)@Co-NC displays impressive Li-storage properties in both half and full cells with a high reversible capacity of 1007.4 mA h g^(-1)at 0.1 A g^(-1)after 100 cycles and superior rate capability up to 5 A g^(-1).Moreover,based on these comprehensive merits,the Co_(9)S_(8-x)@Co-NC composite shows decent electrochemical performance(472.2 and 311.1 mA h g^(-1)at 0.1 and 10 A g^(-1),respectively) as an anode for SIBs.This work presents an effective strategy for the construction of Mott-Schottky-like heterointerfaces in Co_(9)S_(8) based materials and provides specific inspiration for future works designing high-performance electrodes via interfacial engineering.

Growth of SnO_2 Nanoflowers on N-doped Carbon Nanofibers as Anode for Li-and Na-ion Batteries

It is urgent to solve the problems of the dramatic volume expansion and pulverization of SnO_2 anodes during cycling process in battery systems. To address this issue, we design a hybrid structure of N-doped carbon fibers@SnO_2 nanoflowers(NC@SnO_2) to overcome it in this work. The hybrid NC@SnO_2 is synthesized through the hydrothermal growth of SnO_2 nanoflowers on the surface of N-doped carbon fibers obtained by electrospinning. The NC is introduced not only to provide a support framework in guiding the growth of the SnO_2 nanoflowers and prevent the flower-like structures from agglomeration, but also serve as a conductive network to accelerate electronic transmission along one-dimensional structure effectively. When the hybrid NC@SnO_2 was served as anode, it exhibits a high discharge capacity of 750 Ah g^(-1) at 1 A g^(-1) after 100 cycles in Li-ion battery and 270 mAh g^(-1) at 100 mA g^(-1) for 100 cycles in Na-ion battery, respectively.

H_∞ Output Feedback Control of Linear Time-invariant Fractional-order Systems over Finite Frequency Range

This paper focuses on the H_∞ output feedback control problem of linear time-invariant fractional-order systems over finite frequency range. Based on the generalized KalmanYakubovic-Popov(KYP) Lemma and a key projection lemma, a necessary and sufficient condition is established to ensure the existence of the H_∞ output feedback controller over finite frequency range, a desirable property in control engineering practice. By using the matrix congruence transformation, the feedback control gain matrix is decoupled and further parameterized by a scalar matrix. Two iterative linear matrix inequality algorithms are developed to solve this problem. Finally, numerical examples are provided to illustrate the effectiveness of the proposed method.

Altered Neurogranin Phosphorylation and Protein Levels Are Associated with Anxiety- and Depression-Like Behaviors in Rats Following Forced Swim Stress

Here we tested the hypothesis that stress-induced alterations in Neurogranin (Ng) synthesis and/ or utilization might underlie stress-related depression and anxiety. Rats were randomly divided into five conditions: chronic swim stress (CS), acute swim stress (AS), and three control groups. The CS group was exposed to daily swim stress (5 min/day) for 14 consecutive days, the AS group received a single swim stress, and control groups were maintained in a stress-free condition. Both before and after swim stress, rats were tested for body weight gain, open-field locomotor activity, and saccharine preference. Ng and phospho-Ng (P-Ng) levels in the hippocampus and prefrontal cortex were determined by Western blot analysis. Compared to controls, CS animals displayed significantly decreased body weight gain, ambulation, and saccharine intake, and increased grooming behavior. CS animals had decreased Ng levels in the hippocampus and prefrontal cortex. In CS animals, Ng levels were positively correlated with saccharine intake and ambulation, and inversely correlated with grooming behavior. Compared to controls, AS increased immobility behavior and P-Ng and Ng levels in the hippocampus and prefrontal cortex. In AS animals, immobility behavior was positively correlated with the P-Ng in the prefrontal cortex. Thus, CS and AS produced opposing effects on Ng and P-Ng levels in the hippocampus and prefrontal cortex. Low Ng levels in the hippocampus were associated with anhedonic behavior in CS animals, whereas high P-Ng levels in the prefrontal cortex were associated with anxiety-like behavior in AS animals. Thus, Ng dysfunction might contribute to the neural mechanisms underlying stress-induced depression and anxiety.

Nitrogen-doped porous carbon nanosheets as both anode and cathode for advanced potassium-ion hybrid capacitors

Potassium-ion hybrid capacitors(PIHCs)as a burgeoning research hotspot are an ideal replacement for lithium-ion hybrid capacitors(LIHCs).Here,we report nitrogen-doped porous carbon nanosheets(NPCNs)with enlarged interlayer spacing,abundant defects,and favorable mesoporous structures.The structural changes of NPCNs in potassiation and depotassiation processes are analyzed by using Raman spectroscopy and transmission electron microscopy.Due to the unique structure of NPCNs,the PIHC device assembled using NPCNs as both the anode and cathode material(double-functional self-matching material)exhibits a superior energy density of 128 Wh kg^(-1)with a capacity retention of 90.8%after 9000 cycles.This research can promote the development of double-functional self-matching materials for hybrid energy storage devices with ultra-high performance.

The Implementation of Waste Sawdust in Concrete

Nowadays, sawdust has been widely regarded as a sand replacement material to produce sawdust concrete. This thesis uses orthogonal test to analyze the mechanical and heat preservation as well as heat insulation property with the sawdust replacement ratio of 0%, 3%, 5%, 7%, 10%, respectively, to get an optimal sawdust replacement ratio. Besides, it also discusses the deficiencies of this research.

Targeting ASIC1a Promotes Neural Progenitor Cell Migration and Neurogenesis in Ischemic Stroke

Cell replacement therapy using neural progenitor cells(NPCs)has been shown to be an effective treatment for ischemic stroke.However,the therapeutic effect is unsatisfactory due to the imbalanced homeostasis of the local microenvironment after ischemia.Microenvironmental acidosis is a common imbalanced homeostasis in the penumbra and could activate acid-sensing ion channels 1a(ASIC1a),a subunit of proton-gated cation channels following ischemic stroke.However,the role of ASIC1a in NPCs post-ischemia remains elusive.Here,our results indicated that ASIC1a was expressed in NPCs with channel functionality,which could be activated by extracellular acidification.Further evidence revealed that ASIC1a activation inhibited NPC migration and neurogenesis through RhoA signaling-mediated reorganization of filopodia formation,which could be primarily reversed by pharmacological or genetic disruption of ASIC1a.In vivo data showed that the knockout of the ASIC1a gene facilitated NPC migration and neurogenesis in the penumbra to improve behavioral recovery after stroke.

Facile construction of two-dimensional coordination polymers with a well-designed redox-active organic linker for improved lithium ion battery performance

A well-designed redox-active organic linker,pyrazine-2,3,5,6-tetracarboxylate(H_4pztc)with brimming active sites for lithium ions storage was utilized to construct coordination polymers(CPs)via a facile hydrothermal reaction.Those two isostructural two-dimensional(2D)CPs,namely[M_2(pztc)(H_2O)_6]_n(M=Co for 1 and Ni for 2),delivered excellent reversible capacities and stable cycling performance as anodes in lithium ion batteries.As demonstrated in electrochemical studies,1 and 2 can achieve highly reversible capacities of 815 and 536 mA h g^(-1)at 200 mA g^(-1)for 150 cycles,respectively,best performed for the reported2D-CP-based anode materials.The electrochemical mechanism studies showed that the remarkable performances can be ascribed to the synergistic Li-storage redox reactions of metal centers and organic moieties.Our work highlights the opportunities of using a well-designed organic ligand to construct low-dimensional CPs as new type of electrode materials for advanced lithium ion batteries.

Microarray Analysis of Gene Expression Changes in Neuroplastin 65-Knockout Mice: Implications for Abnormal Cognition and Emotional Disorders

Neuroplastin 65 （Np65） is an immunoglobulin superfamily cell adhesion molecule involved in synaptic formation and plasticity. Our recent study showed that Np65-knockout （KO） mice exhibit abnormal cognition and emotional disorders. However, the underlying mechanisms remain unclear. In this study, we found 588 differentially- expressed genes in Np65-KO mice by microarray analysis. RT-PCR analysis also revealed the altered expression of genes associated with development and synaptic structure, such as Cdhl, Htr3a, and Kcnj9. In addition, the expression of Wnt-3, a Wnt protein involved in development, was decreased in Np65-KO mice as evidenced by western blotting. Surprisingly, MRI and DAPI staining showed a significant reduction in the lateral ventricular volume of Np65-KO mice. Together, these findings suggest that ablation of Np65 influences gene expression, which may contribute to abnormal brain development. These results provide clues to the mechanisms underlying the altered brain functions of Np65-deficient mice.

Hochschild Cohomology Rings of Temperley-Lieb Algebras

The authors first construct an explicit minimal projective bimodule resolution(P, δ) of the Temperley-Lieb algebra A, and then apply it to calculate the Hochschild cohomology groups and the cup product of the Hochschild cohomology ring of A based on a comultiplicative map Δ:P → PAP. As a consequence, the authors determine the multiplicative structure of Hochschild cohomology rings of both Temperley-Lieb algebras and representation-finite q-Schur algebras under the cup product by giving an explicit presentation by generators and relations.

Molecular deconvolution of the neutralizing antibodies in duced by an in activated SARS-CoV-2 virus vaccine

Dear Editor,The rapid emerge nee and persistence of the pan demic caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has had enormous impacts on global health and the economy.Effective vaccines against SARS-CoV-2 are urgently needed to control the coronavirus disease 2019(COVID-19)pandemic,and multiple vaccines have been found to be efficacious in preventing symptomatic COVID-19(Polack et al.,2020;Wu et al.,2020;Jones and Roy,2021).

An Explicit Ladder of Homotopy Categories

For an upper triangular matrix ring, an explicit ladder of height 2 of triangle functors between homotopy categories is constructed. Under certain conditions, the author obtains a localization sequence of homotopy categories of acyclic complexes of injective modules.

Koszulity and Koszul modules of dual extension algebras

Let A and B be algebras, and let T be the dual extension algebra of A and B. We provide a different method to prove that T is Koszul if and only if both A and B are Koszul. Furthermore, we prove that an algebra is Koszul if and only if one of its iterated dual extension algebras is Koszul, if and only if all its iterated dual extension algebras are Koszul. Finally, we give a necessary and sufficient condition for a dual extension algebra to have the property that all linearly presented modules are Koszul modules, which provides an effective way to construct algebras with such a property.

弱溶剂化学助力水系锌金属电池在-50~80℃的宽温度范围内稳定运行

开发具有宽温度范围、无枝晶生长和耐腐蚀的电解质对于水系金属锌电池的实际应用至关重要.本研究开发了一种γ-戊内酯共溶剂,以扩大水系电解质的工作温度范围并稳定锌金属阳极的界面.这种弱溶剂作为强氢键配体和“稀释剂”,高效地打破了自由水分子之间的氢键,从而提高了电解液的温度耐受性和化学稳定性.同时,γ-戊内酯也可以吸附在阳极表面从而促进锌的成核和调节锌的生长织构,实现无枝晶的锌沉积.这种优化后的电解质可以使对称电池的寿命达到2160 h,并可以在-50~80℃的宽温度范围内稳定运行.相应的ZnⅡ活性炭电容器和ZnⅡ聚苯胺电池在8100和1600次循环后,容量保持率分别为92.5%和85%.这种弱溶剂调控氢键和锌离子的溶剂鞘的机制为先进的水系电解质的设计提供了新的见解.

开发稳定有机阴离子自由基实现可应用于余辉照明的长持续发光

稳定阴离子自由基的开发在获得高效激基复合物有机超长持续发光材料体系中起到重要作用,但仍然是一个艰巨的挑战.有鉴于此,我们通过提高阴离子自由基的稳定性和降低激基复合物中电荷分离后形成的自由基中间体的再复合速率来开发高效的激基复合物有机长持续发光.我们所开发的激基复合物体系展现出了优异的绿色长持续发光,发光持续时间超过了180分钟.时间分辨的电子顺磁共振测试证实了超长持续发光的获得是因为开发的受体能形成稳定的阴离子自由基和低的自由基阴阳离子再复合速率.将我们所开发的材料应用到发光二极管中,能够制备出智能余辉照明器件.当关闭余辉照明器件的电压180秒后,纸上的英文单词还能被照亮并辨识出来.当前的工作不仅为开发受体材料来实现高效的激基复合物有机长持续发光提供了重要借鉴,也为有机长持续发光在节能余辉照明领域的应用开辟了道路.

Heat Transfer Characteristics of the Microfluidic Biomimetic Chameleon Skin with Active Thermal Camouflage

Natural organisms have different techniques to avoid enemies,such as chameleon skin with innate camouflage ability to change with the surrounding environment.Inspired by this,a microfluidic biomimetic chameleon skin based on infrared(IR)information processing is proposed for active thermal camouflage in a dynamic infrared background.Microfluidic circulation in microcavities distributed under the skin is controlled by a thermal camouflage system.The structure and working principle of the biomimetic skin are introduced,and the thermal camouflage system is established and tested to explore the heat transfer characteristics between the skin and the fluid.The mechanism of collecting the background infrared information and regulating the skin temperature through the control signal generated by the infrared information processing system is illustrated.Furthermore,the dynamic thermal response of the skin is tested when transitioning between different temperature backgrounds,modeling the ambient temperature of the sand,woodland and lakes where chameleons live.The performance of the skin is evaluated by measuring the camouflage responding time of the skin to an external heat source.The results show that the chameleon biomimetic skin is naturally transitioned and matched by infrared information processing and microfluidics.The limitation that the conventional thermal camouflage technology cannot adapt to the dynamic combat environment is overcome and the weaknesses of a small camouflage band range and a single form of camouflage are resolved in this study,thus effectively improving the target’s survivability in combat.

从三维体外培养窥探灵长类原肠运动和器官发生的奥秘

After attaching to the uterus,mammalian blastocysts undergo tremendous morphological changes and cell lineage specification events.Failure to execute these correctly results in abnormal development characterized by fetal malformation or failure of pregnancy.Due to differences to primate development,it is difficult to translate the knowledge obtained in the mouse model to humans.

Adaptive Resource Allocation Algorithm for 5G Vehicular Cloud Communication

The current resource allocation in 5G vehicular networks for mobile cloud communication faces several challenges,such as low user utilization,unbalanced resource allocation,and extended adaptive allocation time.We propose an adaptive allocation algorithm for mobile cloud communication resources in 5G vehicular networks to address these issues.This study analyzes the components of the 5G vehicular network architecture to determine the performance of different components.It is ascertained that the communication modes in 5G vehicular networks for mobile cloud communication include in-band and out-of-band modes.Furthermore,this study analyzes the single-hop and multi-hop modes in mobile cloud communication and calculates the resource transmission rate and bandwidth in different communication modes.The study also determines the scenario of one-way and two-way vehicle lane cloud communication network connectivity,calculates the probability of vehicle network connectivity under different mobile cloud communication radii,and determines the amount of cloud communication resources required by vehicles in different lane scenarios.Based on the communication status of users in 5G vehicular networks,this study calculates the bandwidth and transmission rate of the allocated channels using Shannon’s formula.It determines the adaptive allocation of cloud communication resources,introduces an objective function to obtain the optimal solution after allocation,and completes the adaptive allocation process.The experimental results demonstrate that,with the application of the proposed method,the maximum utilization of user communication resources reaches approximately 99%.The balance coefficient curve approaches 1,and the allocation time remains under 2 s.This indicates that the proposed method has higher adaptive allocation efficiency.

热活化延迟荧光聚合物及其电致发光器件

热活化延迟荧光(TADF)聚合物,不仅具有小分子TADF材料高的激子利用效率特性,而且还具备分子多样性好、可溶液加工、低成本、以及易实现大面积柔性器件等诸多优势,在近几年受到广泛的关注并展现了良好的应用前景。本文从TADF聚合物分子设计原理、器件结构及发光机理出发,依据TADF聚合物的构筑方法不同,概括了其结构设计策略,详述了各种类型TADF聚合物的分子结构和光电性能及其在有机电致发光器件领域应用的研究进展,最后探讨了TADF聚合物存在的问题,并展望了其发展前景。