Hepatitis B cirrhosis combined with Budd-Chiari syndrome treated by liver transplantation:Case report and literature review

Objective:To summarize and analyze the clinical treatment experience of hepatitis B cirrhosis combined with Budd-Chiari syndrome.Methods:Data was obtained from a patient who were diagnosed with hepatitis B cirrhosis combined with Budd-Chiari syndrome.We retrospectively analyzed the clinical character of the patient.Results:The patient was diagnosed with Budd-Chiari syndrome incidentally during operation.so the patient underwent orthotopic liver transplanation,in which the liver and retrohepatic vena cava were resected,and recovered uneventfully.Conclusion:Orthotopic liver transplantation is not only an ideal treatment but also improves the prognosis of patients for hepatitis B cirrhosis combined with Budd-Chiari syndrome.

Screening microRNA expression profile in patients with acute T cell mediated rejection after kidney transplantation

Objective:To explore the expression profile of miRNA in peripheral blood of patients with acute T cell mediated rejection after kidney transplantation.Method:4 patients with acute T cell mediated rejection(TCMR)after kidney transplantation were collected as experimental group.Meanwhile,4 patients under stable condition after kidney transplantation were collected as control group.The elbow blood was taken from two groups.The next generation sequencing was used to study miRNA libraries.Then,they were analyzed of variance by R language software.Results:14 miRNAs were differently expressed in the experimental group and control group,including 5 up-regulated miRNAs(P<0.05)and 9 down-regulated miRNAs(P<0.05).Conclusions:Peripheral blood miRNAs expression variations might be ideal biomarkers and reveal mechanisms for acute TCMR.

Super-minimal incision kidney transplantation: Report of 6 cases

Objective:TReport of 6 cases super-minimal incision kidney transplantation,to further explore its application in renal transplantation.Method:We reviewed the clinical data of 6 cases of SMIKT:operative time,incision size,postoperative pain score,scar score and renal function 1 month after operation.Result:The average operation time of 6 recipients was 95±33min,the average incision size was 6.1±1.1cm,the average pain scores of three days after operation were2.7±0.7,2.2±0.3,2.3±0.5.postoperative analgesia with analgesia pump,no use on the second day,one month after operation,the scar score was 6.85±0.58,and the serum creatinine was 98±16umol/L.Conclusion:The length of incision in the study SMIKT was short,little harm to patients,for the receptor with BMI<25kg/m2,this method can be used.At the same time,the current sample capacity of the study was small and the follow-up time was short,more samples will be needed to enrich the data and further prove its advantages in the future.