We propose a new multipath mitigation technique based on cross-correlation function for the new cosine phased binary off-set carrier (cosine-BOC) modulated signals, which will most likely be employed in both Europea...We propose a new multipath mitigation technique based on cross-correlation function for the new cosine phased binary off-set carrier (cosine-BOC) modulated signals, which will most likely be employed in both European Galileo system and Chinese Compass system. This technique is implemented to create an optimum cross-correlation function via designing the modulated symbols of the local signal. And the structure of the code tracking loop for cosine-BOC signals is quite simple including only two real correlators. Results demonstrate that the technique efficiently eliminates the ranging errors in the medium and long multipath regions with respect to the conventional receiver correlation techniques.展开更多
Spondylis buprestoides adults in Pians masoniana forests in Xianju Dabei Dixi Forestry Center were continuously investigated during 2006 and 2011. According to the survey data, multiple spatial pattern indicators of a...Spondylis buprestoides adults in Pians masoniana forests in Xianju Dabei Dixi Forestry Center were continuously investigated during 2006 and 2011. According to the survey data, multiple spatial pattern indicators of adult population were calculated, and the relationship between various indicators and density was analyzed. The K values of negative binomial distribution less affected by density were selected to describe the spatial pattern and time series dynamics of S. buprestoides adults. The results indicated that S. buprestoides adults showed aggregated distribution in the forest, but the aggregation degree varied with the season. There were 2 obvious diffusion peaks during May and June as well as September and October each year. The aggregation trend within a generation was aggregation-diffusion-aggregation.展开更多
With the rapid social development,people s living habits have undergone great changes.Fast-paced lifestyles have led to an increase in people s unhealthy living habits,especially in diet,such as unreasonable dietary s...With the rapid social development,people s living habits have undergone great changes.Fast-paced lifestyles have led to an increase in people s unhealthy living habits,especially in diet,such as unreasonable dietary structure and irregular diet.In this situation,the number of patients with hyperuricemia has also been increasing,and the hyperuricemia trend is becoming younger.Clinically,western medicines for lowering uric acid are commonly used,which are not safe and have the risk of injuring the liver and kidney functions.Cichorium intybus L.as a medicinal and edible material,plays an important role in treating the hyperuricemia.Recent studies have shown that C.intybus has significant effect of lowering the uric acid.This paper reviewed the experimental studies of C.intybus inhibiting uric acid production and promoting uric acid excretion,discussed its therapeutic effects and action mechanism,to provide a reference for the development of C.intybus drugs for lowering the uric acid.展开更多
Exercise training has been widely recognized as a healthy lifestyle as well as an effective non-drug therapeutic strategy for cardiovascular diseases(CVD).Functional and mechanistic studies that employ animal exercise...Exercise training has been widely recognized as a healthy lifestyle as well as an effective non-drug therapeutic strategy for cardiovascular diseases(CVD).Functional and mechanistic studies that employ animal exercise models as well as observational and interventional cohort studies with human participants,have contributed considerably in delineating the essential signaling pathways by which exercise promotes cardiovascular fitness and health.First,this review summarizes the beneficial impact of exercise on multiple aspects of cardiovascular health.We then discuss in detail the signaling pathways mediating exercise’s benefits for cardiovascular health.The exercise-regulated signaling cascades have been shown to confer myocardial protection and drive systemic adaptations.The signaling molecules that are necessary for exercise-induced physiological cardiac hypertrophy have the potential to attenuate myocardial injury and reverse cardiac remodeling.Exercise-regulated noncoding RNAs and their associated signaling pathways are also discussed in detail for their roles and mechanisms in exercise-induced cardioprotective effects.Moreover,we address the exercise-mediated signaling pathways and molecules that can serve as potential therapeutic targets ranging from pharmacological approaches to gene therapies in CVD.We also discuss multiple factors that influence exercise’s effect and highlight the importance and need for further investigations regarding the exercise-regulated molecules as therapeutic targets and biomarkers for CVD as well as the cross talk between the heart and other tissues or organs during exercise.We conclude that a deep understanding of the signaling pathways involved in exercise’s benefits for cardiovascular health will undoubtedly contribute to the identification and development of novel therapeutic targets and strategies for CVD.展开更多
基金supported by the National Natural Science Foundation of China(6117900461179005)
文摘We propose a new multipath mitigation technique based on cross-correlation function for the new cosine phased binary off-set carrier (cosine-BOC) modulated signals, which will most likely be employed in both European Galileo system and Chinese Compass system. This technique is implemented to create an optimum cross-correlation function via designing the modulated symbols of the local signal. And the structure of the code tracking loop for cosine-BOC signals is quite simple including only two real correlators. Results demonstrate that the technique efficiently eliminates the ranging errors in the medium and long multipath regions with respect to the conventional receiver correlation techniques.
文摘Spondylis buprestoides adults in Pians masoniana forests in Xianju Dabei Dixi Forestry Center were continuously investigated during 2006 and 2011. According to the survey data, multiple spatial pattern indicators of adult population were calculated, and the relationship between various indicators and density was analyzed. The K values of negative binomial distribution less affected by density were selected to describe the spatial pattern and time series dynamics of S. buprestoides adults. The results indicated that S. buprestoides adults showed aggregated distribution in the forest, but the aggregation degree varied with the season. There were 2 obvious diffusion peaks during May and June as well as September and October each year. The aggregation trend within a generation was aggregation-diffusion-aggregation.
基金Supported by Project of Special Fund Project for Innovation Driven Development of Guangxi(Gui Ke AA17202046)Project of Guangxi Natural Science Foundation(2020GXNSFAA238026)+8 种基金Project of Guangxi Key Laboratory of Zhuang&Yao Medicine(GXZYZZ2020-05)The First-Class Subject of Traditional Chinese Medicine(Ethnic Pharmacy)in Guangxi(Gui Jiao Ke Yan[2018]12)Collaborative Innovation Center of Zhuang&Yao Medicine(Gui Jiao Ke Yan[2013]20)Guangxi Province Key Laboratory of Zhuang&Yao Medicine(Gui Ke Ji Zi[2014]32)The Eighth Batch of Special Experts Project of Guangxi Zhuang Autonomous Region(Study on quality standard of Zhuang&Yao medicine,Gui Ren Cai Tong Zi[2019]13)Cultivating Highlevel Talent Teams in the Qi Huang Project of Guangxi University of Chinese Medicine(2018002)Program for Innovative Research Team of High Education and Outstanding Scholar in Guang Xi(Gui Jiao Shi Fan[2019]52)Guangxi One Thousand Young and Middle-aged College and University Backbones Teachers Cultivation Program(Gui Jiao Ren[2019]5)Project of Guangxi Science and Technology Base and Talent(Gui Ke AD20238058)。
文摘With the rapid social development,people s living habits have undergone great changes.Fast-paced lifestyles have led to an increase in people s unhealthy living habits,especially in diet,such as unreasonable dietary structure and irregular diet.In this situation,the number of patients with hyperuricemia has also been increasing,and the hyperuricemia trend is becoming younger.Clinically,western medicines for lowering uric acid are commonly used,which are not safe and have the risk of injuring the liver and kidney functions.Cichorium intybus L.as a medicinal and edible material,plays an important role in treating the hyperuricemia.Recent studies have shown that C.intybus has significant effect of lowering the uric acid.This paper reviewed the experimental studies of C.intybus inhibiting uric acid production and promoting uric acid excretion,discussed its therapeutic effects and action mechanism,to provide a reference for the development of C.intybus drugs for lowering the uric acid.
基金supported by the grants from National Key Research and Development Project(2018YFE0113500 to J.X.)ational Natural Science Foundation of China(82020108002 and 81911540486 to J.X.,81970335 and 82170285 to Y.H.B.)+3 种基金the grant from Science and Technology Commission of Shanghai Municipality(21XD1421300 and 20DZ2255400 to J.X.)the“Dawn”Program of Shanghai Education Commission(19SG34 to J.X.)Shanghai Rising-Star Program(19QA1403900 to Y.H.B.)the grant from Science and Technology Commission of Shanghai Municipality(21SQBS00100 to Y.H.B.).
文摘Exercise training has been widely recognized as a healthy lifestyle as well as an effective non-drug therapeutic strategy for cardiovascular diseases(CVD).Functional and mechanistic studies that employ animal exercise models as well as observational and interventional cohort studies with human participants,have contributed considerably in delineating the essential signaling pathways by which exercise promotes cardiovascular fitness and health.First,this review summarizes the beneficial impact of exercise on multiple aspects of cardiovascular health.We then discuss in detail the signaling pathways mediating exercise’s benefits for cardiovascular health.The exercise-regulated signaling cascades have been shown to confer myocardial protection and drive systemic adaptations.The signaling molecules that are necessary for exercise-induced physiological cardiac hypertrophy have the potential to attenuate myocardial injury and reverse cardiac remodeling.Exercise-regulated noncoding RNAs and their associated signaling pathways are also discussed in detail for their roles and mechanisms in exercise-induced cardioprotective effects.Moreover,we address the exercise-mediated signaling pathways and molecules that can serve as potential therapeutic targets ranging from pharmacological approaches to gene therapies in CVD.We also discuss multiple factors that influence exercise’s effect and highlight the importance and need for further investigations regarding the exercise-regulated molecules as therapeutic targets and biomarkers for CVD as well as the cross talk between the heart and other tissues or organs during exercise.We conclude that a deep understanding of the signaling pathways involved in exercise’s benefits for cardiovascular health will undoubtedly contribute to the identification and development of novel therapeutic targets and strategies for CVD.