Research Progress in Toxicity and Toxicity-reducing and Efficacy-enhancing Compatibility of Radix Aconiti Lateralis Praeparata

Radix Aconiti Lateralis Praeparata contains alkaloids,flavonoids,polysaccharides,organic acids and organic alkalis,among which diester alkaloids are important effective ingredients,which can be used for treating heart failure,rheumatic heart disease,coronary heart disease,hypotension,shock and other diseases.However,it also contains the main ingredients that produce toxic effects and are highly toxic to the cardiovascular system,nervous system,digestive system,reproductive system,embryos,and livers and kidneys.In this study,we analyzed the toxicity-reducing and efficacy-enhancing effects of the compatibility of Radix Aconiti Lateralis Praeparata with with single herbs Glycyrrhiza uralensis Fisch.,Panax ginseng C.A.Meyer,Zingiber ojjicinale Rosc.and Rheum palmatum L.,aiming to provide references for further exploring the appropriate compatibility conditions of traditional Chinese medicine in the future and improving the safety of the clinical application of Radix Aconiti Lateralis Praeparata.

Research Progress of Herb Pair Rhizoma Coptidis-Fructus Evodiae

The herb pair is the basic form of compatibility and application of traditional Chinese medicine.Herb pairs have the advantages of simple structure,clear compatibility and effective characteristics,and are suitable for scientific research.Rhizoma Coptidis-Fructus Evodiae is a relatively fixed combination of two herbs commonly used in clinical Chinese medicine.Chinese medicine uses it to treat various diseases caused by damp-heat accumulation in the liver and gallbladder,and spleen and stomach.The two medicines in the herb pair are opposite in nature but complement each other,and can achieve a great effect based on simple combination.Modern research shows that the herb pair has a wide range of pharmacological effects and good anti-tumor,analgesic,bacteriostatic and anti-inflammatory activity,and show good curative effects on stress ulcers,functional dyspepsia,chronic colitis,etc.This paper reviewed the research progress on the herb pair of Rhizoma Coptidis-Fructus Evodiae.

Clinical Application of Traditional Chinese Medicine in the Treatment of Ovarian Cancer

Ovarian cancer is one of the most common gynecological malignancies and can occur at any time in a woman's life.This paper analyzed the etiology and pathogenesis of ovarian cancer in traditional Chinese medicine,and simply sorted out the methods and means of oral administration and external application of traditional Chinese medicine in the treatment of ovarian cancer,hoping to provide new therapeutic ideas for the treatment of the disease.

Review of Modern Research on Toxicity of Traditional Chinese Medicine Aconm Lateralis Radix Praeparaia

The traditional Chinese medicine Aconm Lateralis Radix Praeparaia(Fuzi)is pungent and sweet in taste,hot in nature,and has high toxicity.It governs the meridians of the heart,kidney and spleen.It has the functions of restoring yang to save from collapse,dispersing cold and removing dampness,and warming the middle to relieve pain.It is often used for the treatment of yang collapse,cold limbs,weak pulse,heart yang deficiency,heart pain due to chest impediment,abdominal cold-pain,kidney yang deficiency,impotence and cold in womb,and syndrome of exogenous disease due to yang deficiency,etc.Its great yang qi and strong medicinal properties often bring about toxic and adverse effects.However,after processing or combination with other medicinal materials,the effects of Aconm Lateralis Radix Praeparaia are quite different.Not only the toxicity is greatly reduced,but also the curative effects are strengthened.Through searching related literature,this paper reviewed the researches about the toxicity reduction and curative effect improvement of Aconm Lateralis Radix Praeparaia,in order to provide a certain theoretic reference for future further research of Aconm Lateralis Radix Praeparaia.

Two-dimensional porous zinc cobalt sulfide nanosheet arrays with superior electrochemical performance for supercapatteries

Unique two-dimensional(2D)porous nanosheets with overwhelmingly rich channels and large specific surface area exhibit superior electrochemical capacitance performance,as compared to the conventional zero-and one-dimensional counterparts.As ternary transition metal sulfides(TMSs)are well recognized for their high electrochemical activity and capacity,and the replacement of oxygen with sulfur may result in high stability and flexible properties of the nanomaterials,as compared to transition metal oxides,herein we report the synthesis of 2D porous nanosheet arrays of Zn_(x)Co_(1-x)S(x=0,0.25,0.5,0.75,and 1)via a facile hydrothermal process.Due to the synergistic effect of the metal components and a unique 2D porous structure,the Zn_(0.5)Co_(0.5)S electrode was found to stand out as the best among the series,with a high specific capacity of 614 C g^(-1)at 1 A g^(-1)and excellent cycle retention rate of 90%over 10,000 cycles at 10 A g^(-1).Notably,a supercapattery based on a Zn_(0.5)Co_(0.5)S positive electrode and an activated carbon(AC)negative electrode(Zn_(0.5)Co_(0.5)S//AC)was found to display a 1.6 V voltage window,a 61 mA h g^(-1)specific capacity at 1 A g^(-1),a 49 Wh kg^(-1)energy density at 957 W kg^(-1)power density,and excellent cycling performance(88%over 10,000 cycles),suggesting tremendous potential of Zn_(0.5)Co_(0.5)S in the development of high-performance supercapattery devices.