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Dendritic spine degeneration:a primary mechanism in the aging process
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作者 Gonzalo Flores Leonardo Aguilar-Hernández +3 位作者 Fernado García-Dolores humberto nicolini Andrea Judith Vázquez-Hernández Hiram Tendilla-Beltrán 《Neural Regeneration Research》 SCIE CAS 2025年第6期1696-1698,共3页
Recent reports suggest that aging is not solely a physiological process in living beings;instead, it should be considered a pathological process or disease(Amorim et al., 2022). Consequently, this process involves a w... Recent reports suggest that aging is not solely a physiological process in living beings;instead, it should be considered a pathological process or disease(Amorim et al., 2022). Consequently, this process involves a wide range of factors, spanning from genetic to environmental factors, and even includes the gut microbiome(GM)(Mayer et al., 2022). All these processes coincide at some point in the inflammatory process, oxidative stress, and apoptosis, at different degrees in various organs and systems that constitute a living organism(Mayer et al., 2022;AguilarHernández et al., 2023). 展开更多
关键词 AGING PROCESS STRESS
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Neuropsychiatric genetics in developing countries: Current challenges 被引量:1
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作者 Diego A Forero Alberto Vélez-van-Meerbeke +2 位作者 Smita N Deshpande humberto nicolini George Perry 《World Journal of Psychiatry》 2014年第4期69-71,共3页
Neuropsychiatric disorders(NPDs) constitute a heavyburden on public health systems around the world and studies have demonstrated that the negative impact of NPDs is larger in Low and Middle Income Countries(LMICs). I... Neuropsychiatric disorders(NPDs) constitute a heavyburden on public health systems around the world and studies have demonstrated that the negative impact of NPDs is larger in Low and Middle Income Countries(LMICs). In recent decades, several studies have come to the understanding that genetic factors play a major role in the risk for a large number of NPDs. However, few neuropsychiatric genetics studies have been published from LMICs. In this Editorial, we discuss important issues impinging on advances in neuropsychiatric genetics research in LMICs. It is essential that scientists educate policymakers and officials of funding agencies on the importance of providing adequate funding for research in these areas. Development of local well-supported research programs focused on NPD genetics should be an important asset to develop; it would facilitate the establishment of sustainable research efforts that could lead to appropriate diagnosis and specific, affordable and feasible interventions in LMICs. It is important to point out that research into the biological basis of human NPDs is not only an academic effort reserved for a few elite institutions in economically developed countries, but it is vitally important for the mental health of people around the world. 展开更多
关键词 NEUROGENETICS Psychiatric genetics Mental health Neurosciences Public health
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