期刊文献+
共找到1篇文章
< 1 >
每页显示 20 50 100
Recent advances in the development of activatable multifunctional probes for in vivo imaging of caspase-3 被引量:2
1
作者 Pengzhan Wang huocheng yang +5 位作者 Chang Liu Mingqiang Qiu Xin Ma Zhiqiang Mao Yao Sun Zhihong Liu 《Chinese Chemical Letters》 SCIE CAS CSCD 2021年第1期168-178,共11页
Caspases are a family of proteases that play critical roles in controlling inflammation and cell death.Apoptosis is a caspase-3 mainly controlled behavior to avoid inflammation and damage to surrounding cells,whereas ... Caspases are a family of proteases that play critical roles in controlling inflammation and cell death.Apoptosis is a caspase-3 mainly controlled behavior to avoid inflammation and damage to surrounding cells,whereas anomalistic cell apoptosis may be associated with many diseases.The detection and imaging of caspase-3 will be of great significance in evaluating the early therapeutic effect of tumors.Developing smart fluorescent probes may be helpful for the visualization of the rapeutic effect compared with "always on" probes.Thus,more and more works toward activatable fluorescent probes for caspase-3 imaging have been reported.In addition,multifunctional probes have also been designed to further improve the imaging of caspase-3.Herein,this review systematically summarized the representative wo rk of caspase-3 from the perspective of molecular design that it will play a guiding role in the design of probes that respond to caspase-3.Also,challenges and perspectives toward the field for imaging of cell apoptosis(caspase-3) are also discussed. 展开更多
关键词 Fluorescence imaging Multi-functional Activatable probe CASPASE-3
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部