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对易通过结肠曲的新型结肠镜的评估:一项随机研究
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作者 Hoff g. Bretthauer M. +1 位作者 huppertz-hauss g. 廖新华 《世界核心医学期刊文摘(胃肠病学分册)》 2006年第3期32-33,共2页
Background and study aims: A new colonoscope (XCFQ-160AW prototype, Olympus, Tokyo, Japan) has been developed, designed with an additional passive bending function to ease intubation through the left colonic flexure. ... Background and study aims: A new colonoscope (XCFQ-160AW prototype, Olympus, Tokyo, Japan) has been developed, designed with an additional passive bending function to ease intubation through the left colonic flexure. In this study we investigated whether this function could be included in a standard colonoscope without jeopardizing general performance, particularly passage through the sigmoid colon. Patients and methods: 280 outpatients referred for routine colonoscopy at Telemark Hospital were randomly allocated to colonoscopy with a standard colonoscope (Olympus 140 series) or the XCFQ160AW prototype. Sedation was given on demand. End points were cecal intubation and the patients’grading of pain in a questionnaire. Results: Cecal intubation rates were 85 %and 87 %for standard and prototype endoscopes, respectively (P=0.57). On-demand sedation was given to nine (7%) and 15 (11%) of the patients, respectively (P=0.17). Of the patients, 256 (85%) returned their questionnaire,with 87 (63%) in the standard group and 109 (77%) in the prototype group reporting that they had experienced ‘no pain/slight pain’(P < 0.001). In a multiple logistic regression analysis, this difference in experienced pain remained statistically significant after adjustment for interendoscopist variation and the use of the endoscope-stiffening function. Two patients in the study, in whom there had previously been several unsuccessful attempts at negotiating the splenic flexure, were successfully examined with the prototype colonoscope. Conclusion: Examination with the Olympus XCF-Q160AW prototype with a passive bending function caused less pain than use of a standard Olympus 140 series colonoscope, without compromising other endoscope functions for colonic intubation. 展开更多
关键词 结肠镜检查 随机研究 肠曲 对易 观察终点 插管率 常规组 结肠左曲 镇静药物 结肠脾曲
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