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Therapeutic Effects of Traditional Herbal Medicine on Cerebral Ischemia:A Perspective of Vascular Protection 被引量:5
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作者 Youngmin Bu Kyungjin Lee +1 位作者 hyuk-sang jung Sang-Kwan Moon 《Chinese Journal of Integrative Medicine》 SCIE CAS 2013年第11期804-814,共11页
Although many agents for acute ischemic stroke treatment have been developed from extensive preclinical studies, most have failed in clinical trials. As a result, researchers are seeking other methods or agents based ... Although many agents for acute ischemic stroke treatment have been developed from extensive preclinical studies, most have failed in clinical trials. As a result, researchers are seeking other methods or agents based on previous studies. Among the various prospective approaches, vascular protection might be the key for development of therapeutic agents for stroke and for improvements in the efficacy and safety of conventional therapies. Traditional medicines in Asian countries are based on clinical experiences and literature accumulated over thousands of years. To date, many studies have used traditional herbal medicines to prove or develop new agents based on stroke treatments mentioned in traditional medicinal theory or other clinical data. In the current review, we describe the vascular factors related to ischemic brain damage and the herbal medicines that impact these factors, including Salviae Miltiorrhizae Radix, Notoginseng Radix, and Curcumae Rhizoma, based on scientific reports and traditional medical theory. Further, we point out the problems associated with herbal medicines in stroke research and propose better methodologies to address these problems. 展开更多
关键词 traditional medicine vascular protection ischemic stroke Salviae Miltiorrhizae Radix Notoginseng Radix Curcumae Rhizoma
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