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Role of technical factors on the Sister Chromatid Exchanges frequency in Human and Primates.
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作者 Ch.Laurent i.joris +1 位作者 D.Bazzoni J.Collignon 《癌变.畸变.突变》 CAS CSCD 1991年第S1期273-273,共1页
Biomonitoring human exposed to alkylating agents with theSister Chromatid Exchanges assay(SCEs)and especially theHigh Frequency Cells concept(HFCs)is considered as asensitive approach for detecting a personal exposure... Biomonitoring human exposed to alkylating agents with theSister Chromatid Exchanges assay(SCEs)and especially theHigh Frequency Cells concept(HFCs)is considered as asensitive approach for detecting a personal exposure.Six yearsafter a two-year chronic exposure of primates to EtO,a highlymutagenic agent,an persistently increased SCEs frequency hasrecently been published.In this experiment,the appearance of ahighly mutated subpopulation of cells(the High Frequency 展开更多
关键词 APPEARANCE detecting exposure exposed mutated shortest RESTRICTED RELEVANCE ETHYLENE COMPLEMENTARY
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