Bacterial lipoproteins are proteins that are post-trans-lationally modified with a diacylglyceride at an N-terminal cysteine,which serves to tether these proteins to the outer face of the plasma membrane or to the out...Bacterial lipoproteins are proteins that are post-trans-lationally modified with a diacylglyceride at an N-terminal cysteine,which serves to tether these proteins to the outer face of the plasma membrane or to the outer membrane.This paper reviews recent insights into the enzymology of bacterial lipoprotein biosynthe-sis and localization.Moreover,we use bioinformatic analyses of bacterial lipoprotein signal peptide features and of the key biosynthetic enzymes to consider the distribution of lipoprotein biosynthesis at the phylum level.展开更多
文摘Bacterial lipoproteins are proteins that are post-trans-lationally modified with a diacylglyceride at an N-terminal cysteine,which serves to tether these proteins to the outer face of the plasma membrane or to the outer membrane.This paper reviews recent insights into the enzymology of bacterial lipoprotein biosynthe-sis and localization.Moreover,we use bioinformatic analyses of bacterial lipoprotein signal peptide features and of the key biosynthetic enzymes to consider the distribution of lipoprotein biosynthesis at the phylum level.
