Alzheimer’s disease(AD)is the most common form of age-related dementia with the latest report(World Alzheimer Report,2015)showing 46.8 million people are currently affected by dementia.That number is expected to ...Alzheimer’s disease(AD)is the most common form of age-related dementia with the latest report(World Alzheimer Report,2015)showing 46.8 million people are currently affected by dementia.That number is expected to double every 20 years unless there is effective therapeutic intervention.The 42 amino acid peptide known as amyloid beta(or Aβ)has been implicated as one of the main causative agents of AD after its discovery in plaques in 1985(Masters et al.,1985).展开更多
文摘Alzheimer’s disease(AD)is the most common form of age-related dementia with the latest report(World Alzheimer Report,2015)showing 46.8 million people are currently affected by dementia.That number is expected to double every 20 years unless there is effective therapeutic intervention.The 42 amino acid peptide known as amyloid beta(or Aβ)has been implicated as one of the main causative agents of AD after its discovery in plaques in 1985(Masters et al.,1985).