The use of bee venom as a therapeutic agent for the relief of joint pains dates back to Hippocrates,and ref-erences to the treatment can be found in ancient Egyp-tian and Greek medical writings as well.Also known as a...The use of bee venom as a therapeutic agent for the relief of joint pains dates back to Hippocrates,and ref-erences to the treatment can be found in ancient Egyp-tian and Greek medical writings as well.Also known as apitherapy,the technique is widely used in Eastern Europe,Asia,and South America.The beneficial effects of bee stings can be attributed to mellitinin,an anti-in-flammatory agent,known to be hundred times stronger than cortisone.Unfortunately,certain substances in the bee venom trigger allergic reactions which can be life threatening in a sensitized individual.Multiple stings are known to cause hemolysis,kidney injury,hepatotoxicity and myocardial infarction.The toxicity can be immedi-ate or can manifest itself only weeks after the exposure.We describe hepatotoxicity in a 35-year-old female,following bee sting therapy for multiple sclerosis.She presented to our clinic 3 wk after therapy with a his-tory of progressive jaundice.The patient subsequently improved,and has been attending our clinic now for the last 9 mo.展开更多
We report progressive painless jaundice in a 39 year old female with a suspicion of metastatic liver disease on ultrasound and computed tomography scan of the abdomen. Although the most frequent liver lesions are live...We report progressive painless jaundice in a 39 year old female with a suspicion of metastatic liver disease on ultrasound and computed tomography scan of the abdomen. Although the most frequent liver lesions are liver metastasis because of dual blood supply of the liver and the impact of hormones, the index case proved to have acute autoimmune hepatitis (AIH) after liver biopsy was undertaken. AIH, an unresolving inflammation of liver, occurs predominantly among females worldwide. It may present acutely and even fulminant hepatitis has been described. The index case had a dramatic response to steroid treatment with total recovery and complete resolution of liver lesions. She is clinically fine and has been regularly attending our clinic for the last year. To our knowledge from a Medline search, this is the first report where AIH was seen to mimic metastatic liver disease.展开更多
文摘The use of bee venom as a therapeutic agent for the relief of joint pains dates back to Hippocrates,and ref-erences to the treatment can be found in ancient Egyp-tian and Greek medical writings as well.Also known as apitherapy,the technique is widely used in Eastern Europe,Asia,and South America.The beneficial effects of bee stings can be attributed to mellitinin,an anti-in-flammatory agent,known to be hundred times stronger than cortisone.Unfortunately,certain substances in the bee venom trigger allergic reactions which can be life threatening in a sensitized individual.Multiple stings are known to cause hemolysis,kidney injury,hepatotoxicity and myocardial infarction.The toxicity can be immedi-ate or can manifest itself only weeks after the exposure.We describe hepatotoxicity in a 35-year-old female,following bee sting therapy for multiple sclerosis.She presented to our clinic 3 wk after therapy with a his-tory of progressive jaundice.The patient subsequently improved,and has been attending our clinic now for the last 9 mo.
文摘We report progressive painless jaundice in a 39 year old female with a suspicion of metastatic liver disease on ultrasound and computed tomography scan of the abdomen. Although the most frequent liver lesions are liver metastasis because of dual blood supply of the liver and the impact of hormones, the index case proved to have acute autoimmune hepatitis (AIH) after liver biopsy was undertaken. AIH, an unresolving inflammation of liver, occurs predominantly among females worldwide. It may present acutely and even fulminant hepatitis has been described. The index case had a dramatic response to steroid treatment with total recovery and complete resolution of liver lesions. She is clinically fine and has been regularly attending our clinic for the last year. To our knowledge from a Medline search, this is the first report where AIH was seen to mimic metastatic liver disease.
