PURPOSE: To report on a case of bilateral conjunctival lymphoid hyperplasia pr esenting with bilateral panuveitis in a female patient. DESIGN: Observational ca se report. METHODS: In this case excisional biopsy indica...PURPOSE: To report on a case of bilateral conjunctival lymphoid hyperplasia pr esenting with bilateral panuveitis in a female patient. DESIGN: Observational ca se report. METHODS: In this case excisional biopsy indicated lymphoid tissue. Im munohistochemistry showed a follicular architecture with appropriate zoning of B and T lymphocytes. RESULTS: Causes of panuveitis were considered and excluded b ased on a detailed history, physical examination, and laboratory investigations. The bilateral panuveitis resolved on topical corticosteroids and visual acuity returned to normal. CONCLUSIONS: Ocular adnexal lymphoproliferative lesions cons ist of a spectrum of disease entities, including reactive lymphoid hyperplasia, atypical lymphoid hyperplasia, and lymphoma. There are no established clinical c riteria to differentiate between these lesions. This case highlights the importa nce of a thorough ophthalmic examination in these patients, as an intra-ocular inflammatory process may accompany the conjunctival findings. Futhermore, we adv ocate periodic follow-up examinations because of the small potential risk of de veloping ocular or systemic lymphoma in these patients.展开更多
Purpose: To report a case of unilateral keratoconus in a 7- yearold female, secondary to chronic persistent eye- rubbing in the absence of any systemic condition. Design: Observational case report. Methods: In the cas...Purpose: To report a case of unilateral keratoconus in a 7- yearold female, secondary to chronic persistent eye- rubbing in the absence of any systemic condition. Design: Observational case report. Methods: In the case of this child, no organic cause was found to explain the onset of keratoconus other than persistent eye- rubbing in the affected eye. Results: Nocturnal eye padding was instigated and the condition stabilized. She was reviewed over a 2- year period of follow- up. Conclusions: Eye- rubbing has been implicated in the pathogenesis of keratoconus. Eyerubbing is also often a feature of a number of conditions linked to keratoconus such as Down syndrome, atopic keratoconjunc- tivitis, mental retardation, and Lebers’ congenital amaurosis. There are a number of reports linking eye- rubbing and keratoconus in children, typically in relation to these conditions. However, in this case the keratoconus was secondary to chronic and persistent eye- rubbing in a healthy child.展开更多
文摘PURPOSE: To report on a case of bilateral conjunctival lymphoid hyperplasia pr esenting with bilateral panuveitis in a female patient. DESIGN: Observational ca se report. METHODS: In this case excisional biopsy indicated lymphoid tissue. Im munohistochemistry showed a follicular architecture with appropriate zoning of B and T lymphocytes. RESULTS: Causes of panuveitis were considered and excluded b ased on a detailed history, physical examination, and laboratory investigations. The bilateral panuveitis resolved on topical corticosteroids and visual acuity returned to normal. CONCLUSIONS: Ocular adnexal lymphoproliferative lesions cons ist of a spectrum of disease entities, including reactive lymphoid hyperplasia, atypical lymphoid hyperplasia, and lymphoma. There are no established clinical c riteria to differentiate between these lesions. This case highlights the importa nce of a thorough ophthalmic examination in these patients, as an intra-ocular inflammatory process may accompany the conjunctival findings. Futhermore, we adv ocate periodic follow-up examinations because of the small potential risk of de veloping ocular or systemic lymphoma in these patients.
文摘Purpose: To report a case of unilateral keratoconus in a 7- yearold female, secondary to chronic persistent eye- rubbing in the absence of any systemic condition. Design: Observational case report. Methods: In the case of this child, no organic cause was found to explain the onset of keratoconus other than persistent eye- rubbing in the affected eye. Results: Nocturnal eye padding was instigated and the condition stabilized. She was reviewed over a 2- year period of follow- up. Conclusions: Eye- rubbing has been implicated in the pathogenesis of keratoconus. Eyerubbing is also often a feature of a number of conditions linked to keratoconus such as Down syndrome, atopic keratoconjunc- tivitis, mental retardation, and Lebers’ congenital amaurosis. There are a number of reports linking eye- rubbing and keratoconus in children, typically in relation to these conditions. However, in this case the keratoconus was secondary to chronic and persistent eye- rubbing in a healthy child.
