Comparison of Clinical Efficacy between Laparoscopy and Open Operation in the Treatment of Early Ovarian Cancer

The purpose of the study was to investigate the clinical efficacy of laparoscopy and laparotomy in the treatment of early ovarian cancer.The clinical data of 86 patients with early-stage ovarian cancer admitted to the department of Obstetrics and Gynecology of Zhanjiang Central People’s Hospital from January 2012 to January 2015 were retrospectively analyzed.According to different surgical methods,42 patients undergoing laparoscopic surgery were included in the observation group and 44 patients undergoing open surgery were included in the control group.Serum level of hs-CRP were measured before treatment(T0),immediately after treatment(T1)and 24 h after treatment(T2),respectively.The perioperative indicators and recurrence rates were compared between the two groups.The results showed that the serum levels of hs-CRP in the T1 and T2 observation groups were 29.6±8.4 mg/L and 32.8±10.1 mg/L,respectively,which were significantly lower than those in the control group(35.4±10.3 mg/L and 39.7±12.6 mg/L),with statistically significant differences(P<0.05).The operative time of the observation group was 252.4±26.9 min,which was significantly longer than that of the control group 201.5±32.7 min,and the difference was statistically significant(P<0.05).The intraoperative blood loss in the observation group was 16.2±31.2 mL,which was significantly less than that in the control group 215.9±43.8 mL.The number of lymph node dissection in the observation group was 35.2±1.4,which was higher than that in the control group 22.4±9.2.The postoperative exhaust time was 36.4±1.5 h in observation group,which was shorter than that in the control group 49.2±13.7 h,and the differences in all the above indicators were statistically significant(P<0.05).The incidence of postoperative complications in the observation group was 7.14%,significantly lower than that in the control group(22.73%),and the difference was statistically significant(P<0.05).After 18 months of follow-up,the postoperative recurrence rate in the observation group and the control group was 9.52%and 6.82%,respectively,with no statistically significant difference(P>0.05).Therefore,laparoscopic surgery in the treatment of early ovarian cancer can achieve the same clinical effect as open surgery,and has the advantages of mild stress response,less bleeding,and lower incidence of postoperative complications.