Electric-Jet Assisted Layer-by-Layer Deposition of Gold Nanoparticles to Prepare Conducting Tracks

A suspension of 15nm diameter gold nanoparti-cles has been deposited along a line on a silicon substrate with the assistance of a jet generated in an electric field. In order to control the evaporation of the solvent used to suspend the gold nanoparticles, a heating device was used to change the substrate temperature. Layer-by- layer deposition enabled the direct writing of gold tracks having an electrical resistivity of 1.8 × 10-7 Ωm, only about an order of magnitude above the electrical resistivity of bulk gold.

The versatility of Fe(Ⅱ) in the synthesis of uniform citrate-stabilized plasmonic nanoparticles with tunable size at room temperature

A highly versatile seed-mediated approach for the synthesis of citrate-stabilized gold,silver and palladium nanoparticles(NPs)with size control is reported.The use of iron(Ⅱ)as a reducing agent enables the fabrication of monodisperse NPs in a wide range of sizes(from 15 nm to at least 120 nm(90 nm for Pd))at room temperature.The citrate as capping ligand on the NPs surface facilitates its further surface modification with proteins and thiolated molecules.

SERS sensing for cancer biomarker:Approaches and directions

These days,cancer is thought to be more than just one illness,with several complex subtypes that require different screening approaches.These subtypes can be distinguished by the distinct markings left by metabolites,proteins,miRNA,and DNA.Personalized illness management may be possible if cancer is categorized according to its biomarkers.In order to stop cancer from spreading and posing a significant risk to patient survival,early detection and prompt treatment are essential.Traditional cancer screening techniques are tedious,time-consuming,and require expert personnel for analysis.This has led scientists to reevaluate screening methodologies and make use of emerging technologies to achieve better results.Using time and money saving techniques,these methodologies integrate the procedures from sample preparation to detection in small devices with high accuracy and sensitivity.With its proven potential for biomedical use,surface-enhanced Raman scattering(SERS)has been widely used in biosensing applications,particularly in biomarker identification.Consideration was given especially to the potential of SERS as a portable clinical diagnostic tool.The approaches to SERS-based sensing technologies for both invasive and non-invasive samples are reviewed in this article,along with sample preparation techniques and obstacles.Aside from these significant constraints in the detection approach and techniques,the review also takes into account the complexity of biological fluids,the availability of biomarkers,and their sensitivity and selectivity,which are generally lowered.Massive ways to maintain sensing capabilities in clinical samples are being developed recently to get over this restriction.SERS is known to be a reliable diagnostic method for treatment judgments.Nonetheless,there is still room for advancement in terms of portability,creation of diagnostic apps,and interdisciplinary AI-based applications.Therefore,we will outline the current state of technological maturity for SERS-based cancer biomarker detection in this article.The review will meet the demand for reviewing various sample types(invasive and non-invasive)of cancer biomarkers and their detection using SERS.It will also shed light on the growing body of research on portable methods for clinical application and quick cancer detection.