Nerve growth factor(NGF) is a neurotrophic factor critical for cholinergic neuronal survival, phenotypic maintenance and plasticity in the mammalian brain. NGF has been implicated in the pathogenesis of neurodegenerat...Nerve growth factor(NGF) is a neurotrophic factor critical for cholinergic neuronal survival, phenotypic maintenance and plasticity in the mammalian brain. NGF has been implicated in the pathogenesis of neurodegenerative disorders, with direct administration of NGF into the brain capable of facilitating neuroprotection and repair.展开更多
基金supported by the Canadian Institutes of Health Research(grant FRN 137064 to IA)the FDC Foundation+3 种基金the WB Family FoundationGerald and Carla Connor,the Weston Brain Institute(TR130117 to IA)a Frederick Banting and Charles Best Canada Graduate Scholarship(GSD 152271 to KX)in part,from funding through the Canada Research Chairs program(to IA)。
文摘Nerve growth factor(NGF) is a neurotrophic factor critical for cholinergic neuronal survival, phenotypic maintenance and plasticity in the mammalian brain. NGF has been implicated in the pathogenesis of neurodegenerative disorders, with direct administration of NGF into the brain capable of facilitating neuroprotection and repair.
