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A study on p53 gene alterations in esophageal squamous cell carcinoma and their correlation to common dietary risk factors among population of the Kashmir valley 被引量:9
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作者 Imtiyaz Murtaza Dhuha Mushtaq +4 位作者 Mushtaq A Margoob Amit Dutt Nisar ahmad Wani ishfaq ahmad Mohan Lal Bhat 《World Journal of Gastroenterology》 SCIE CAS CSCD 2006年第25期4033-4037,共5页
瞄准:为了系统地检验风险因素的关联的程度,例如年龄,与原因的体的 Tp53 分子损害消费了饮食的习惯和家庭倾向在北印度的 Kashmiri 人口之中提高食道的有鳞的房间癌(ESCC ) 的致癌作用严厉。方法:所有情况(n = 51 ) 并且控制(n = 15... 瞄准:为了系统地检验风险因素的关联的程度,例如年龄,与原因的体的 Tp53 分子损害消费了饮食的习惯和家庭倾向在北印度的 Kashmiri 人口之中提高食道的有鳞的房间癌(ESCC ) 的致癌作用严厉。方法:所有情况(n = 51 ) 并且控制(n = 150 ) 是克什米尔山谷的永久居民。基因改变在 Tp53 肿瘤的前 ons 5-8 被决定压制或在 45 个 ESCC 盒子之中的基因组织学地由 PCR-SSCP 分析证实了。为单个癌症盒子的数据(n = 45 ) 并且住院病人控制(n = 150 ) 与非癌症,疾病在癌症的家庭历史上包括了信息,与病人的年龄组一起的三十个占优势的普通饮食的风险因素。在到从这些参数的万物有灵论的数据的 p53 前 ons 的基因损害的关联被 Chi 平方测试与健康控制一起产生到所有 45 个组织学地证实的 ESCC 盒子。结果:(77.8%) 45 中的 35 个组织学地描绘了与 45 正常样品中的 1 个对比的有的类似的体细胞突变从一样的耐心的显示出的细菌线变化从邻近的区域获得了的肿瘤样品。 SSCP 分析表明了改变在 6 上在前被发现的那很普通的 p53 基因(77.7%),那没与个人和 clinicopathological 参数的年龄相关,但是与癌症的家庭历史显示出重要词语索引( P【0.05 )( CD = 58 ),在消费的一个未知地点,和饮食的习惯建议细菌线倾向局部地种芥属蔬菜“ Hakh ”( CD = 19.5 ),红 chillies ( CD = 20.2 ),热咸苏打茶( CD = 2.37 )并且本地烤的面包( CD = 1.1 )。结论:我们的学习建议那体的染色体变化特别在 6 Tp53 基因上的前,在人种上的食道的癌症病人之中,克什米尔山谷的同质的人口是仔细与到各种各样的普通饮食的风险因素,特别热的咸茶,肉,烤的面包和“ Hakh ”的继续的暴露有关,那富于 nitrosoamines 和家庭癌症历史。 展开更多
关键词 P53基因 食道癌 饮食习惯 治疗
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Optimized viewport-adaptive 360-degree video streaming 被引量:2
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作者 Xiaolei Chen Di Wu ishfaq ahmad 《CAAI Transactions on Intelligence Technology》 EI 2021年第3期347-359,共13页
Because of the rapid growth of head-mounted displays and 5G networking deployment,360-degree video has become increasingly popular.To generate the real experience of a virtual environment,360-degree videos require an ... Because of the rapid growth of head-mounted displays and 5G networking deployment,360-degree video has become increasingly popular.To generate the real experience of a virtual environment,360-degree videos require an ultrahigh resolution and frame rate to cover an omnidirectional view.These two prerequisites impose challenges for the transmission bandwidth and storage capacity of 360-degree video streaming.To reduce bandwidth and storage waste while providing a good immersive experience,we propose an optimized viewport-adaptive 360-degree video streaming method using high-efficiency video coding tiling,motion-constrained tile sets and MPEG dynamic adaptive streaming over HTTP spatial relationship description.The paper describes the rigorous design of the optimized system,which can assign different bitrates to different tiles in the viewport.The experimental results show that the proposed streaming system compares favourably with existing methods in terms of bitrate savings and storage capacity reduction. 展开更多
关键词 VIDEO STREAMING system
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A New Class of L-Moments Based Calibration Variance Estimators 被引量:1
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作者 Usman Shahzad ishfaq ahmad +2 位作者 Ibrahim Mufrah Almanjahie Nadia H.Al Noor Muhammad Hanif 《Computers, Materials & Continua》 SCIE EI 2021年第3期3013-3028,共16页
Variance is one of themost important measures of descriptive statistics and commonly used for statistical analysis.The traditional second-order central moment based variance estimation is a widely utilized methodology... Variance is one of themost important measures of descriptive statistics and commonly used for statistical analysis.The traditional second-order central moment based variance estimation is a widely utilized methodology.However,traditional variance estimator is highly affected in the presence of extreme values.So this paper initially,proposes two classes of calibration estimators based on an adaptation of the estimators recently proposed by Koyuncu and then presents a new class of L-Moments based calibration variance estimators utilizing L-Moments characteristics(L-location,Lscale,L-CV)and auxiliary information.It is demonstrated that the proposed L-Moments based calibration variance estimators are more efficient than adapted ones.Artificial data is considered for assessing the performance of the proposed estimators.We also demonstrated an application related to apple fruit for purposes of the article.Using artificial and real data sets,percentage relative efficiency(PRE)of the proposed class of estimators with respect to adapted ones are calculated.The PRE results indicate to the superiority of the proposed class over adapted ones in the presence of extreme values.In this manner,the proposed class of estimators could be applied over an expansive range of survey sampling whenever auxiliary information is available in the presence of extreme values. 展开更多
关键词 L-MOMENTS variance estimation calibration approach stratified random sampling
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Roadside dust contamination with toxic metals along industrial area in Islamabad, Pakistan
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作者 Waheed Akram Morgan Madhuku +4 位作者 Kashif Shahzad Ali Awais ishfaq ahmad Muhammad Arif Ishaq ahmad 《Nuclear Science and Techniques》 SCIE CAS CSCD 2014年第3期8-13,共6页
An investigation has been carried out to understand the contamination characteristics of roadside dust in the industrial area of Islamabad, Pakistan. The amounts of Si, S, Cl, K, Ca, Sc, Ti, V, Cr, Mn, Fe, Co, Ni, Cu,... An investigation has been carried out to understand the contamination characteristics of roadside dust in the industrial area of Islamabad, Pakistan. The amounts of Si, S, Cl, K, Ca, Sc, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Pb,Zn, Ga, As, Se and Cd were determined from 95 roadside dust samples collected along the Islamabad industrial area using Proton Induced X-ray Emission(PIXE). The results indicated that concentrations of all elements,except Cd, in the roadside dust were significant. The results of the enrichment factor show that the elementary composition of the roadside dust could be categorized as soil elements from the crust of the earth and elements from anthropogenic pollution. The high enrichment factors imply that elements such Cr, Cu, Pb, Zn, As, Se,Cd, Ni, Co and S came from anthropogenic activities. The source of metal contamination was identified using multivariate statistical analysis. It has been concluded that Ca, Sc, Ti, V, Mn and Fe mainly originate from crustal sources; Cr, Cu, Ni, Pb, Zn and Ga are associated with point-sources from industrial pollution/traffic;and S, Cl, K, As and Se are mainly related to oil/coal combustion. 展开更多
关键词 伊斯兰堡 灰尘污染 巴基斯坦 工业区 有毒金属 土壤元素 多元统计分析 X射线发射
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L-Moments Based Calibrated Variance Estimators Using Double Stratified Sampling
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作者 Usman Shahzad ishfaq ahmad +1 位作者 Ibrahim Mufrah Almanjahie Nadia H.Al–Noor 《Computers, Materials & Continua》 SCIE EI 2021年第9期3411-3430,共20页
Variance is one of the most vital measures of dispersion widely employed in practical aspects.A commonly used approach for variance estimation is the traditional method of moments that is strongly influenced by the pr... Variance is one of the most vital measures of dispersion widely employed in practical aspects.A commonly used approach for variance estimation is the traditional method of moments that is strongly influenced by the presence of extreme values,and thus its results cannot be relied on.Finding momentum from Koyuncu’s recent work,the present paper focuses first on proposing two classes of variance estimators based on linear moments(L-moments),and then employing them with auxiliary data under double stratified sampling to introduce a new class of calibration variance estimators using important properties of L-moments(L-location,L-cv,L-variance).Three populations are taken into account to assess the efficiency of the new estimators.The first and second populations are concerned with artificial data,and the third populations is concerned with real data.The percentage relative efficiency of the proposed estimators over existing ones is evaluated.In the presence of extreme values,our findings depict the superiority and high efficiency of the proposed classes over traditional classes.Hence,when auxiliary data is available along with extreme values,the proposed classes of estimators may be implemented in an extensive variety of sampling surveys. 展开更多
关键词 Variance estimation L-MOMENTS calibration approach double sampling stratified random sampling
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Standardization of proton-induced x-ray emission technique for analysis of thick samples
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作者 Shad Ali Johar Zeb +3 位作者 Abdul Ahad ishfaq ahmad M.Haneef Jehan Akbar 《Chinese Physics B》 SCIE EI CAS CSCD 2015年第9期171-176,共6页
This paper describes the standardization of the proton-induced x-ray emission(PIXE) technique for finding the elemental composition of thick samples. For the standardization, three different samples of standard refe... This paper describes the standardization of the proton-induced x-ray emission(PIXE) technique for finding the elemental composition of thick samples. For the standardization, three different samples of standard reference materials(SRMs) were analyzed using this technique and the data were compared with the already known data of these certified SRMs. These samples were selected in order to cover the maximum range of elements in the periodic table. Each sample was irradiated for three different values of collected beam charges at three different times. A proton beam of 2.57 Me V obtained using 5UDH-II Pelletron accelerator was used for excitation of x-rays from the sample. The acquired experimental data were analyzed using the GUPIXWIN software. The results show that the SRM data and the data obtained using the PIXE technique are in good agreement. 展开更多
关键词 STANDARDIZATION thick samples PIXE analysis
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