Our laboratory has pursued T cell therapy withantigen-specific T cell clones as means to treat humandisease.Our studies in the prevention of CMV disease in immunosuppressed patients with hematologic malignancies under...Our laboratory has pursued T cell therapy withantigen-specific T cell clones as means to treat humandisease.Our studies in the prevention of CMV disease in immunosuppressed patients with hematologic malignancies undergoing bone marrow transplantation(BMT),in which patients receive infusions of CMV-speeific CD8^(+)and CD4^(+)T cell clones derived from the BMT donor,have highlighted the potential for amplifying human immune responses by transfer of antigen-specific T cells.展开更多
文摘Our laboratory has pursued T cell therapy withantigen-specific T cell clones as means to treat humandisease.Our studies in the prevention of CMV disease in immunosuppressed patients with hematologic malignancies undergoing bone marrow transplantation(BMT),in which patients receive infusions of CMV-speeific CD8^(+)and CD4^(+)T cell clones derived from the BMT donor,have highlighted the potential for amplifying human immune responses by transfer of antigen-specific T cells.
