Purpose: To investigate whether the mixed beta-blocker, metipranolol, possesses calcium and sodium channel blocking activities and blunts the effects of retinal ischaemia as reported for the betal-antagonist, betaxolo...Purpose: To investigate whether the mixed beta-blocker, metipranolol, possesses calcium and sodium channel blocking activities and blunts the effects of retinal ischaemia as reported for the betal-antagonist, betaxolol (Expt. Eye Research 1999, 69, 331-342). Methods: Rat retinas or rat brain synaptosomes were exposed to radioactive calcium or sodium and NM-展开更多
文摘Purpose: To investigate whether the mixed beta-blocker, metipranolol, possesses calcium and sodium channel blocking activities and blunts the effects of retinal ischaemia as reported for the betal-antagonist, betaxolol (Expt. Eye Research 1999, 69, 331-342). Methods: Rat retinas or rat brain synaptosomes were exposed to radioactive calcium or sodium and NM-