Nontuberculous mycobacteria(NTM)are opportunistic pathogens of environmental origin that can cause human infections in a wide variety of tissues[1].Lung involvement is the most common manifestation of NTM infection[1]...Nontuberculous mycobacteria(NTM)are opportunistic pathogens of environmental origin that can cause human infections in a wide variety of tissues[1].Lung involvement is the most common manifestation of NTM infection[1].The symptoms and radiographic signs are similar to those of patients with pulmonary tuberculosis(TB)who are infected with Mycobacterium tuberculosis complex(MTBC)[1].Most NTM species are naturally resistant to first-line anti-TB drugs and have different resistance profiles,thus misdiagnosis leads to inappropriate treatment and increases the risk of poor prognosis for patients with an NTM infection,and even wider spread through person-to-person contact[2].展开更多
基金funded in part by the Sanming Project of Medicine in Shenzhen[SZSM201611030]the Fundamental Research Funds for the Central Universities[2042021kf0041]Guangdong Medical Science and Technology Research Fund[B2021075].
文摘Nontuberculous mycobacteria(NTM)are opportunistic pathogens of environmental origin that can cause human infections in a wide variety of tissues[1].Lung involvement is the most common manifestation of NTM infection[1].The symptoms and radiographic signs are similar to those of patients with pulmonary tuberculosis(TB)who are infected with Mycobacterium tuberculosis complex(MTBC)[1].Most NTM species are naturally resistant to first-line anti-TB drugs and have different resistance profiles,thus misdiagnosis leads to inappropriate treatment and increases the risk of poor prognosis for patients with an NTM infection,and even wider spread through person-to-person contact[2].