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Interdisciplinary Research Unveils How SID-1 Recognizes dsRNA and Initiates Systemic RNAi
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作者 jiang daohua 《Bulletin of the Chinese Academy of Sciences》 2024年第2期112-113,共2页
RNA interference(RNAi)is a fascinating biological process in worms,plants,fungi,and metazoans that has been used as a valuable tool in studying gene functions and as therapeutics.In Caenorhabditis elegans,the multipas... RNA interference(RNAi)is a fascinating biological process in worms,plants,fungi,and metazoans that has been used as a valuable tool in studying gene functions and as therapeutics.In Caenorhabditis elegans,the multipass transmembrane protein,systemic RNA interference defective protein 1(SID-1),has an indispensable role in the uptake and spreading of double-stranded RNA(dsRNA)between cells and tissues,resulting in systemic RNAi. 展开更多
关键词 SID indispensable valuable
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VMAT2 Transport and Inhibition Mechanisms Revealed by Cryo-EM
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作者 jiang daohua 《Bulletin of the Chinese Academy of Sciences》 2023年第4期237-237,共1页
Neurotransmitters are a class of signaling chemicals,including monoamines such as serotonin,dopamine,and histamine,which play a vital role in a variety of neurological activities,including mood,memory,growth and devel... Neurotransmitters are a class of signaling chemicals,including monoamines such as serotonin,dopamine,and histamine,which play a vital role in a variety of neurological activities,including mood,memory,growth and development,and drug addiction.The cytosolic neurotransmitters in presynaptic neurons must be transported into synaptic vesicles for storage and subsequent release. 展开更多
关键词 DOPAMINE SEROTONIN subsequent
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