The Impact of Directly Observed Therapy on Preventive Treatment for Latent Tuberculosis Infection among Students in Dalian, China

Preventive treatment has an essential effect on latent tuberculosis infection(LTBI)[purified protein derivative(PPD)induration≥15 mm].Between2010 and 2013,there were 6 tuberculosis(TB)outbreaks in the universities in Dalian,China.So far,in Dalian,the directly observed therapy(DOT)and

超声TI-RADS 4级甲状腺结节的回顾性分析

目的回顾性分析超声TI-RADS 4级甲状腺结节(Φ≤1 cm)患者184例,探究TI-RADS 4级甲状腺结节需临床干预的高危因素,避免临床对TI-RADS 4级甲状腺结节的盲目治疗。方法收集攀枝花攀钢集团总医院2010年1月-2018年9月间,门诊首次经超声诊断的TI-R ADS 4级甲状腺结节(Φ≤1 cm)患者184例的临床病理资料进行回顾性研究。结果 184例患者中,随访终止78例,随访终止患者中甲状腺癌34例,结节性甲状腺肿39例,甲状腺腺瘤5例;TI-RADS 4级甲状腺结节患者随访中出现疾病进展与性别、年龄、颈部放射史、合并甲状腺其他疾病、甲状腺癌家族史、TI-RADS分级及TSH水平密切相关,差异有统计学意义(P<0.05);与结节个数及结节位置不相关,差异无统计学意义(P≥0.05)。多因素Logistic回归分析显示年龄、TI-R ADS分级、性别、TSH水平是TI-R ADS 4级甲状腺结节患者的独立危险因素。结论年龄<45岁、TI-R ADS分级高、男性、TSH高水平与甲状腺结节疾病进展关系密切,存在以上高危因素者应避免长期随访,尽快手术治疗。