目的探讨改良早期预警评分(Modified Early Warning Score,MEWS)联合Braden评分对ICU老年患者压力性损伤的预测作用。方法收集某三级甲等医院201例ICU老年患者的一般资料、MEWS评分、Braden评分以及住院期间发生压力性损伤的资料。通过...目的探讨改良早期预警评分(Modified Early Warning Score,MEWS)联合Braden评分对ICU老年患者压力性损伤的预测作用。方法收集某三级甲等医院201例ICU老年患者的一般资料、MEWS评分、Braden评分以及住院期间发生压力性损伤的资料。通过受试者工作特征(receiver operating characteristic,ROC)曲线,评价MEWS评分、Braden评分及两者联合对老年患者压力性损伤的预测作用。结果MEWS评分联合Braden评分预测老年患者压力性损伤发生的ROC曲线下面积(area under the curve,AUC)为0.948[95%CI(0.891,0.982)],显著高于单独应用MEWS评分、Braden评分的0.834[95%CI(0.762,0.942)]、0.863[95%CI(0.783,0.939)](P<0.001);联合应用的灵敏度和特异度分别为92.6%和93.1%。结论MEWS评分联合Braden评分能够有效预测ICU老年患者压力性损伤的发生。展开更多
[ Objective] The aim was to use response surface methodology to determine optimum conditions for extraction of polysaccharides from Tegillarca granosa. [ Method] Response surface methodology with three-factors and thr...[ Objective] The aim was to use response surface methodology to determine optimum conditions for extraction of polysaccharides from Tegillarca granosa. [ Method] Response surface methodology with three-factors and throe-levels was carried out for optimizing the extraction process of polysacchafides from Tegillarca granosa. A central composite des（gn including independent variables, such as extraction temperature （A）, extraction time （B）, and ethanol concentration （C） was obtained through Box-Benhnken central combination design. Selected response which evaluates the extraction process was polysacchadde yield. [ Result] The independent variable with the largest effect on response was ethanol concentration （C）. The optimum extraction conditions were found to be extraction temperature 69.6℃, extraction time 6.2 h, and ethanol concen- tration of 78% （V/V）, respectively. Under these conditions, the extraction efficiency of polysaccharide can increase to 1. 635%. [ Coaclusioa] Study on the extraction of polysaccharides from Tegillarca granosa could provide certain theoretical direction for extracting polysaccharides from Tegillarca granosa on a large scale.展开更多
文摘目的探讨改良早期预警评分(Modified Early Warning Score,MEWS)联合Braden评分对ICU老年患者压力性损伤的预测作用。方法收集某三级甲等医院201例ICU老年患者的一般资料、MEWS评分、Braden评分以及住院期间发生压力性损伤的资料。通过受试者工作特征(receiver operating characteristic,ROC)曲线,评价MEWS评分、Braden评分及两者联合对老年患者压力性损伤的预测作用。结果MEWS评分联合Braden评分预测老年患者压力性损伤发生的ROC曲线下面积(area under the curve,AUC)为0.948[95%CI(0.891,0.982)],显著高于单独应用MEWS评分、Braden评分的0.834[95%CI(0.762,0.942)]、0.863[95%CI(0.783,0.939)](P<0.001);联合应用的灵敏度和特异度分别为92.6%和93.1%。结论MEWS评分联合Braden评分能够有效预测ICU老年患者压力性损伤的发生。
基金Supported by Key Scientific Research Program of Wannan MedicalCollege ( WK2012Z208)
文摘[ Objective] The aim was to use response surface methodology to determine optimum conditions for extraction of polysaccharides from Tegillarca granosa. [ Method] Response surface methodology with three-factors and throe-levels was carried out for optimizing the extraction process of polysacchafides from Tegillarca granosa. A central composite des（gn including independent variables, such as extraction temperature （A）, extraction time （B）, and ethanol concentration （C） was obtained through Box-Benhnken central combination design. Selected response which evaluates the extraction process was polysacchadde yield. [ Result] The independent variable with the largest effect on response was ethanol concentration （C）. The optimum extraction conditions were found to be extraction temperature 69.6℃, extraction time 6.2 h, and ethanol concen- tration of 78% （V/V）, respectively. Under these conditions, the extraction efficiency of polysaccharide can increase to 1. 635%. [ Coaclusioa] Study on the extraction of polysaccharides from Tegillarca granosa could provide certain theoretical direction for extracting polysaccharides from Tegillarca granosa on a large scale.
