[Objectives]This study was conducted to select small seedless watermelon varieties with excellent quality and high yield suitable for planting in Beijing.[Methods]Under the conditions of facility cultivation in Beijin...[Objectives]This study was conducted to select small seedless watermelon varieties with excellent quality and high yield suitable for planting in Beijing.[Methods]Under the conditions of facility cultivation in Beijing,a screening test was conducted on seven small seedless watermelon varieties for growth process,field traits,yield traits,fruit quality,and disease resistance.[Results]Varieties Mitong,Motong and Tianbao Xiaowuzi had a short growth period and relatively stable growth,and bore fruit easily,and their female flowers were closely spaced.Their yields exceeded 60000 kg/hm~2,ranking in the top three among all varieties.The fruit had a thin skin,a bright red flesh color,and a high mass fraction of soluble solids in the center.The flesh was tight or crispy,and tasted good.They also showed good disease resistance.Overall,they showed excellent comprehensive agronomic traits,and are thus suitable for facility cultivation in Beijing and its surrounding areas.[Conclusions]This study provides a theoretical basis for the upgrading of varieties and the increase in production and farmers'income in the suburbs of Beijing.展开更多
[Objectives]This study was conducted to select suitable medium-sized watermelon varieties for early spring cultivation in Beijing.[Methods]Seven watermelon varieties were collected,including Beinong Tianjiao 2,Beinong...[Objectives]This study was conducted to select suitable medium-sized watermelon varieties for early spring cultivation in Beijing.[Methods]Seven watermelon varieties were collected,including Beinong Tianjiao 2,Beinong Tianjiao,Hongfuji,Yongfeng 1,Beinong Futian,Beinong Shijia,and Beinong Jinxiu,and Jingxin 2 was used as the control check(CK).The growth period,morphological traits,yield traits and fruit quality of the tested varieties were investigated.[Results]Beinong Tianjiao 2 had an earlier maturation stage,a fruit development period of 38 d and a total growth period of 118 d.It showed stable growth,with a single fruit weight of 7.56 kg,a fruit setting rate of 0.99 per plant,and a yield of 83076.9 kg/hm~2,which ranked,respectively,second,first,and second among all tested varieties,and were significantly superior to the CK.Furthermore,this variety had thin and tough peel,a bright red flesh color,high central sugar content,loose and crisp flesh,and a good taste.[Conclusions]It is preliminarily believed that it is suitable for early spring watermelon production in Beijing area.展开更多
Bod et al.1 recently published a study in Nature that garnered attention to B cell-associated anti-tumor immunity and immunotherapy of melanoma and other tumors1.As a promising supplemental immunotherapy to mainstream...Bod et al.1 recently published a study in Nature that garnered attention to B cell-associated anti-tumor immunity and immunotherapy of melanoma and other tumors1.As a promising supplemental immunotherapy to mainstream methods that target T and natural killer(NK)cells,B cell-associated anti-tumor immunotherapy is promising。展开更多
The Fabry–Perot(FP) resonant cavity is widely used in laser and spectroscopic measurements due to its unique interference transfer function(ITF). In the ideal case of parallel incident light, the ITF of the FP resona...The Fabry–Perot(FP) resonant cavity is widely used in laser and spectroscopic measurements due to its unique interference transfer function(ITF). In the ideal case of parallel incident light, the ITF of the FP resonant cavity can be expressed by the Airy function. However, in reality, it is difficult to achieve perfect parallelism with collimated beams. In this article, a theoretical model is established for non-parallel light incidence, which assumes that the non-parallel incident light is a cone-shaped beam, and the cone angle is used to quantify the non-parallelism of the beam. The transmittance function of the FP resonant cavity under non-parallel light incidence is derived. The accuracy of the model is experimentally verified. Based on this model, the effects of divergence angle, tilt angle and FP cavity parameters(reflectivity, cavity length)on the ITF are studied. The reasons for the decrease in peak value, broadening and asymmetry of the interference peak under non-parallel light incidence are explained. It is suggested that a fine balance between the interference peak and the collimation effect of the incident light should be considered in the design and application of FP resonant cavities, especially for tilted applications such as angle-scanned spectroscopy. The research results of this article have certain significance for the design and application of FP resonant cavities.展开更多
The remarkable capabilities of 2D plasmonic surfaces in controlling optical waves havegarnered significant attention.However,the challenge of large-scale manufacturing of uniform,well-aligned,and tunable plasmonic sur...The remarkable capabilities of 2D plasmonic surfaces in controlling optical waves havegarnered significant attention.However,the challenge of large-scale manufacturing of uniform,well-aligned,and tunable plasmonic surfaces has hindered their industrialization.To address this,we present a groundbreaking tunable plasmonic platform design achieved throughmagnetic field(MF)assisted ultrafast laser direct deposition in air.Through precise control of metal nanoparticles(NPs),with cobalt(Co)serving as the model material,employing an MF,and fine-tuning ultrafast laser parameters,we have effectively converted coarse and non-uniform NPs into densely packed,uniform,and ultrafine NPs(~3 nm).This revolutionary advancement results in the creation of customizable plasmonic‘hot spots,’which play a pivotal role insurface-enhanced Raman spectroscopy(SERS)sensors.The profound impact of this designable plasmonic platform lies in its close association with plasmonic resonance and energyenhancement.When the plasmonic nanostructures resonate with incident light,they generate intense local electromagnetic fields,thus vastly increasing the Raman scattering signal.This enhancement leads to an outstanding 2–18 fold boost in SERS performance and unparalleled sensing sensitivity down to 10^(-10)M.Notably,the plasmonic platform also demonstratesrobustness,retaining its sensing capability even after undergoing 50 cycles of rinsing andre-loading of chemicals.Moreover,this work adheres to green manufacturing standards,making it an efficient and environmentally friendly method for customizing plasmonic‘hot spots’inSERS devices.Our study not only achieves the formation of high-density,uniform,and ultrafine NP arrays on a tunable plasmonic platform but also showcases the profound relation betweenplasmonic resonance and energy enhancement.The outstanding results observed in SERS sensors further emphasize the immense potential of this technology for energy-relatedapplications,including photocatalysis,photovoltaics,and clean water,propelling us closer to a sustainable and cleaner future.展开更多
Objective:This study aimed to investigate the role of receptor tyrosine kinase-like orphan receptor 2(ROR2)in triple-negative breast cancer(TNBC).Methods:ROR2 expression in primary TNBC and metastatic TNBC tissues was...Objective:This study aimed to investigate the role of receptor tyrosine kinase-like orphan receptor 2(ROR2)in triple-negative breast cancer(TNBC).Methods:ROR2 expression in primary TNBC and metastatic TNBC tissues was analyzed by immunohistochemical staining and PCR.ROR2 expression in TNBC cell lines was detected by PCR and Western blot analysis.The migration,invasion and chemosensitivity of TNBC cells with overexpression or knockdown of ROR2 were examined.Results:ROR2 expression was high in metastatic TNBC tissues.ROR2 knockdown suppressed the migration,invasion and chemoresistance of TNBC cells.ROR2 overexpression in MDA-MB-435 cells promoted the migration,invasion,and chemoresistance.Moreover,ROR2 knockdown in HC1599 and MDA-MB-435 adriamycin-resistant cells enhanced chemosensitivity to adriamycin.ROR2 could activate PI3K/AKT/mTOR signaling in TNBC cells.Conclusion:ROR2 is upregulated and promotes metastatic phenotypes of TNBC by activating PI3K/AKT/mTOR signaling.展开更多
文中提出一种二维空间相干信号波达方向(Direction of Arrival,DOA)估计方法。该方法首先对L形阵接收数据协方差矩阵进行共轭重构,将原协方差矩阵的平方与重构矩阵的平方相加后求均值,得到新协方差矩阵。然后采用前后向空间平滑技术对...文中提出一种二维空间相干信号波达方向(Direction of Arrival,DOA)估计方法。该方法首先对L形阵接收数据协方差矩阵进行共轭重构,将原协方差矩阵的平方与重构矩阵的平方相加后求均值,得到新协方差矩阵。然后采用前后向空间平滑技术对新协方差矩阵进行预处理,最后通过Root-MUSIC算法进行DOA估计。仿真实验和湖试数据分析结果表明,与常规方法相比,文中方法避免了谱峰搜索,减小了计算量,提高了相干信号DOA估计的分辨成功概率和估计精度,具有较高的工程应用价值。展开更多
A time-synchronization strategy for packetized transmission of target position about a large-aperture telescope observation control system has been proposed in this study.Compared with the existing telescope tracking ...A time-synchronization strategy for packetized transmission of target position about a large-aperture telescope observation control system has been proposed in this study.Compared with the existing telescope tracking strategy,the target position packing and sending strategy based on the time synchronization method proposed in this paper has the advantages of high stability and reliability.First,the telescope tracking observation control method was elaborated in this paper,including the motion pattern during telescope tracking.Then,the strategy for packetizes transmission of target positions based on time-synchronization is established and lists the detailed steps.Finally,the performance of the tracking strategy is verified using the 2.5 m telescope for the simulated uniform speed star and the blind-tracking fixed star HIP 31216,respectively.The test results show that the accuracy root mean square of the tracking strategy proposed in this paper is less than 0".02 at 30 minutes,and the performance is much better than the design requirement of 0".3.The most important advantage of this tracking strategy is that the telescope can guarantee normal tracking for a certain period of time even if the hardware or software of the host computer is abnormal.展开更多
基金Supported by Special Crop Innovation Team of Beijing(BAIC04-2022)。
文摘[Objectives]This study was conducted to select small seedless watermelon varieties with excellent quality and high yield suitable for planting in Beijing.[Methods]Under the conditions of facility cultivation in Beijing,a screening test was conducted on seven small seedless watermelon varieties for growth process,field traits,yield traits,fruit quality,and disease resistance.[Results]Varieties Mitong,Motong and Tianbao Xiaowuzi had a short growth period and relatively stable growth,and bore fruit easily,and their female flowers were closely spaced.Their yields exceeded 60000 kg/hm~2,ranking in the top three among all varieties.The fruit had a thin skin,a bright red flesh color,and a high mass fraction of soluble solids in the center.The flesh was tight or crispy,and tasted good.They also showed good disease resistance.Overall,they showed excellent comprehensive agronomic traits,and are thus suitable for facility cultivation in Beijing and its surrounding areas.[Conclusions]This study provides a theoretical basis for the upgrading of varieties and the increase in production and farmers'income in the suburbs of Beijing.
文摘[Objectives]This study was conducted to select suitable medium-sized watermelon varieties for early spring cultivation in Beijing.[Methods]Seven watermelon varieties were collected,including Beinong Tianjiao 2,Beinong Tianjiao,Hongfuji,Yongfeng 1,Beinong Futian,Beinong Shijia,and Beinong Jinxiu,and Jingxin 2 was used as the control check(CK).The growth period,morphological traits,yield traits and fruit quality of the tested varieties were investigated.[Results]Beinong Tianjiao 2 had an earlier maturation stage,a fruit development period of 38 d and a total growth period of 118 d.It showed stable growth,with a single fruit weight of 7.56 kg,a fruit setting rate of 0.99 per plant,and a yield of 83076.9 kg/hm~2,which ranked,respectively,second,first,and second among all tested varieties,and were significantly superior to the CK.Furthermore,this variety had thin and tough peel,a bright red flesh color,high central sugar content,loose and crisp flesh,and a good taste.[Conclusions]It is preliminarily believed that it is suitable for early spring watermelon production in Beijing area.
文摘Bod et al.1 recently published a study in Nature that garnered attention to B cell-associated anti-tumor immunity and immunotherapy of melanoma and other tumors1.As a promising supplemental immunotherapy to mainstream methods that target T and natural killer(NK)cells,B cell-associated anti-tumor immunotherapy is promising。
基金Project supported by the National Natural Science Foundation of China (Grant No.U19A2044)the National Natural Science Foundation of China (Grant No.41975037)the Key Technologies Research and Development Program of Anhui Province (Grant No.202004i07020013)。
文摘The Fabry–Perot(FP) resonant cavity is widely used in laser and spectroscopic measurements due to its unique interference transfer function(ITF). In the ideal case of parallel incident light, the ITF of the FP resonant cavity can be expressed by the Airy function. However, in reality, it is difficult to achieve perfect parallelism with collimated beams. In this article, a theoretical model is established for non-parallel light incidence, which assumes that the non-parallel incident light is a cone-shaped beam, and the cone angle is used to quantify the non-parallelism of the beam. The transmittance function of the FP resonant cavity under non-parallel light incidence is derived. The accuracy of the model is experimentally verified. Based on this model, the effects of divergence angle, tilt angle and FP cavity parameters(reflectivity, cavity length)on the ITF are studied. The reasons for the decrease in peak value, broadening and asymmetry of the interference peak under non-parallel light incidence are explained. It is suggested that a fine balance between the interference peak and the collimation effect of the incident light should be considered in the design and application of FP resonant cavities, especially for tilted applications such as angle-scanned spectroscopy. The research results of this article have certain significance for the design and application of FP resonant cavities.
基金the support by the Office of Naval Research’s NEPTUNE Program under the Grant Number N00014-16-1-3109the National Science Foundation CMMI NanoManufacturing Program。
文摘The remarkable capabilities of 2D plasmonic surfaces in controlling optical waves havegarnered significant attention.However,the challenge of large-scale manufacturing of uniform,well-aligned,and tunable plasmonic surfaces has hindered their industrialization.To address this,we present a groundbreaking tunable plasmonic platform design achieved throughmagnetic field(MF)assisted ultrafast laser direct deposition in air.Through precise control of metal nanoparticles(NPs),with cobalt(Co)serving as the model material,employing an MF,and fine-tuning ultrafast laser parameters,we have effectively converted coarse and non-uniform NPs into densely packed,uniform,and ultrafine NPs(~3 nm).This revolutionary advancement results in the creation of customizable plasmonic‘hot spots,’which play a pivotal role insurface-enhanced Raman spectroscopy(SERS)sensors.The profound impact of this designable plasmonic platform lies in its close association with plasmonic resonance and energyenhancement.When the plasmonic nanostructures resonate with incident light,they generate intense local electromagnetic fields,thus vastly increasing the Raman scattering signal.This enhancement leads to an outstanding 2–18 fold boost in SERS performance and unparalleled sensing sensitivity down to 10^(-10)M.Notably,the plasmonic platform also demonstratesrobustness,retaining its sensing capability even after undergoing 50 cycles of rinsing andre-loading of chemicals.Moreover,this work adheres to green manufacturing standards,making it an efficient and environmentally friendly method for customizing plasmonic‘hot spots’inSERS devices.Our study not only achieves the formation of high-density,uniform,and ultrafine NP arrays on a tunable plasmonic platform but also showcases the profound relation betweenplasmonic resonance and energy enhancement.The outstanding results observed in SERS sensors further emphasize the immense potential of this technology for energy-relatedapplications,including photocatalysis,photovoltaics,and clean water,propelling us closer to a sustainable and cleaner future.
基金supported by Medical and Health Research Project of Nanjing Health Science and Technology Development Special Fund(ZKX21040).
文摘Objective:This study aimed to investigate the role of receptor tyrosine kinase-like orphan receptor 2(ROR2)in triple-negative breast cancer(TNBC).Methods:ROR2 expression in primary TNBC and metastatic TNBC tissues was analyzed by immunohistochemical staining and PCR.ROR2 expression in TNBC cell lines was detected by PCR and Western blot analysis.The migration,invasion and chemosensitivity of TNBC cells with overexpression or knockdown of ROR2 were examined.Results:ROR2 expression was high in metastatic TNBC tissues.ROR2 knockdown suppressed the migration,invasion and chemoresistance of TNBC cells.ROR2 overexpression in MDA-MB-435 cells promoted the migration,invasion,and chemoresistance.Moreover,ROR2 knockdown in HC1599 and MDA-MB-435 adriamycin-resistant cells enhanced chemosensitivity to adriamycin.ROR2 could activate PI3K/AKT/mTOR signaling in TNBC cells.Conclusion:ROR2 is upregulated and promotes metastatic phenotypes of TNBC by activating PI3K/AKT/mTOR signaling.
文摘文中提出一种二维空间相干信号波达方向(Direction of Arrival,DOA)估计方法。该方法首先对L形阵接收数据协方差矩阵进行共轭重构,将原协方差矩阵的平方与重构矩阵的平方相加后求均值,得到新协方差矩阵。然后采用前后向空间平滑技术对新协方差矩阵进行预处理,最后通过Root-MUSIC算法进行DOA估计。仿真实验和湖试数据分析结果表明,与常规方法相比,文中方法避免了谱峰搜索,减小了计算量,提高了相干信号DOA估计的分辨成功概率和估计精度,具有较高的工程应用价值。
基金supported by the National Natural Science Foundation of China(grant Nos.11973065 and U1931207)Jiangsu Funding Program for Excellent Postdoctoral Talent(2022ZB449)to this paper+1 种基金financial support from China Scholarship Council(No.CSC201904910254)Chinese Academy of Sciences Public Study Abroad Fund(Lingzhe Xu)。
文摘A time-synchronization strategy for packetized transmission of target position about a large-aperture telescope observation control system has been proposed in this study.Compared with the existing telescope tracking strategy,the target position packing and sending strategy based on the time synchronization method proposed in this paper has the advantages of high stability and reliability.First,the telescope tracking observation control method was elaborated in this paper,including the motion pattern during telescope tracking.Then,the strategy for packetizes transmission of target positions based on time-synchronization is established and lists the detailed steps.Finally,the performance of the tracking strategy is verified using the 2.5 m telescope for the simulated uniform speed star and the blind-tracking fixed star HIP 31216,respectively.The test results show that the accuracy root mean square of the tracking strategy proposed in this paper is less than 0".02 at 30 minutes,and the performance is much better than the design requirement of 0".3.The most important advantage of this tracking strategy is that the telescope can guarantee normal tracking for a certain period of time even if the hardware or software of the host computer is abnormal.
