Several simple analogues of peroxyplakoric acid were synthesized by using Kobayashi's method to construct the key 1,2-dioxane core and tested in vitro for antimalarial activity. The scope and limitation of the method...Several simple analogues of peroxyplakoric acid were synthesized by using Kobayashi's method to construct the key 1,2-dioxane core and tested in vitro for antimalarial activity. The scope and limitation of the method was also briefly examined.展开更多
基金Project supported by the National Natural Science Foundation of China (Nos. 20025207, 20272071, 20372075, 20321202), the Chinese Academy ot Sciences (“Knowledge Innovation”project, KGCX2-SW-209), and the Major State Basic Research Development Program (No. G2000077502) of China.
文摘Several simple analogues of peroxyplakoric acid were synthesized by using Kobayashi's method to construct the key 1,2-dioxane core and tested in vitro for antimalarial activity. The scope and limitation of the method was also briefly examined.