Background: Surgery is the treatment for early-stage cervical cancer. Radiochemotherapy is used in the treatment of locally advanced stages. But the choice of treatment can be difficult. Objective: The objective of th...Background: Surgery is the treatment for early-stage cervical cancer. Radiochemotherapy is used in the treatment of locally advanced stages. But the choice of treatment can be difficult. Objective: The objective of this work was to evaluate the therapeutic aspects of cervical cancer in the early stages IA to IIA in the oncology department of A Ledantec Hospital in Dakar. Patients and methods: This was a descriptive retrospective study, from January 2015 to December 2020, in the oncology department of A Ledantec Hospital, including all the patients who had been treated for early-stage invasive cervical cancer. Results: We included 28 patients. The average age was 49.54 years old. There were 11 patients (39.3%) with a stage ≤ IB1. Surgery was the first in 14 patients (50%). The initial approach was a midline supra and subumbilical laparotomy. The surgery was R0 in 65.22%. Postoperative complications were found in 4 patients including 1 case of operative wound suppuration, 1 case of dysuria, 1 case of postoperative eventration and 1 case of rectovaginal fistula. Concomitant Radiochemotherapy was neoadjuvant in 7 cases (25%), adjuvant in 14 cases (50%). The chemotherapy was neoadjuvant in 09 cases (56.25%) and adjuvant in 7 cases (43.75%) with minor toxicities. We had recorded 2 deaths. Conclusion: The treatment of the early stages of invasive cervical cancer is based on surgery. Neoadjuvant treatments may be useful in particular situations.展开更多
<strong>Introduction:</strong><span style="font-family:Verdana;"> The principal postoperative complication of mastectomies with</span><span style="font-family:Verdana;"&g...<strong>Introduction:</strong><span style="font-family:Verdana;"> The principal postoperative complication of mastectomies with</span><span style="font-family:Verdana;"> axillary dissection is the lymphocele that can last many months after surgery. The purpose of our study was to prevent its formation using the padding.</span><span style="font-family:""> </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> Sixty-one patients have been included in our study. The follow-up was 6 months. The patients were divided in two groups through a random draw (simple drainage and drainage associated with padding). All patients had a mastectomy with axillary dissection following the Madden technique. All quantities of lymphoceles during postoperative hospitalization and ambulatory care have been noted.</span><span style="font-family:""> </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> Twenty-five patients had benefited f</span><span style="font-family:Verdana;">rom</span><span style="font-family:Verdana;"> the padding and 36 of a simple axillary drainage. Six months after the surgery, the patients benefitting from the padding had a quantity of lymphocele equal to half that of the control group (761.83 mL against 1373.60 mL;p = 0.01). During the postoperative hospitalization, the quantities were of 362.80 mL for the padding group versus 630.83 mL;p < 0.01. The hospitalization period was shorter for the padding patients (3.72 days vs 5.14 days;p = 0.01). However, pain was greater for the padding group upon 6 months (0.26 vs 0.10;p = 0.04). On another note, padding does not influence the duration of the surgery.</span><span style="font-family:""> </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> The production of postoperative lymphocele is heterogenous, varying from one patient to another. Nevertheless, the padding of the mastectomy compartment and of the axillary cavity allow</span><span style="font-family:Verdana;">s</span><span style="font-family:Verdana;"> a noticeable reduction of the produced quantity and of the hospitalization period at the expense of more pain.</span>展开更多
The intercostobrachial nerve (ICBN) is responsible for the sensory</span></span></span></span></span><span><span><span><span><span><span style="font-...The intercostobrachial nerve (ICBN) is responsible for the sensory</span></span></span></span></span><span><span><span><span><span><span style="font-family:""><span style="font-family:Verdana;"> innervation of a part of the inner side of the arm. Injury of the intercostobrachial nerve is </span><span style="font-family:Verdana;">a complication of axillary dissection during lymph node dissection.</span> <b><span style="font-family:Verdana;">Objective</span></b><span style="font-family:Verdana;">: </span><span style="font-family:Verdana;">This study aimed to determine the effect of preservation of the</span><span style="font-family:Verdana;"> intercostobra</span><span><span style="font-family:Verdana;">chial nerve on postoperative sensory disturbances. </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> This is a</span></span><span style="font-family:Verdana;"> prospective, single-center study which was carried out in 90 patients followed in the oncology department of the Aristide Le Dantec hospital in Dakar, suffering </span><span style="font-family:Verdana;">from breast cancer and having undergone breast surgery associated with</span><span style="font-family:Verdana;"> axillary </span><span style="font-family:Verdana;">dissection, for a period of 6 months. The patients were divided into two</span><span style="font-family:Verdana;"> groups depending on whether the intercostobrachial nerve (ICBN) was preserved or </span><span style="font-family:Verdana;">not. The two groups were compared in terms of the incidence of sensory</span><span style="font-family:Verdana;"> disturbances. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> Sixty patients without nerve preservation and 30 patients with nerve preservation were included in the study, </span><i><span style="font-family:Verdana;">i.e.</span></i><span style="font-family:Verdana;">, 90 patients in total. </span><span style="font-family:Verdana;">ICBN was injured in 60 patients of which 41 patients (83.7%) developed</span><span style="font-family:Verdana;"> numbness in the inner arm. While in the preserved group, only 8 patients suffered from numbness (16.3%) with a significant P value of 0.002;however, for </span><span style="font-family:Verdana;">other </span><span style="font-family:Verdana;">variables such as the incidence of neuropathic pain and hypoesthesia-like</span><span style="font-family:Verdana;"> sensory </span><span><span style="font-family:Verdana;">deficit, there was no significant difference. </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> Preservation of the </span></span><span style="font-family:Verdana;">intercostobrachial nerve during axillary dissection for breast cancer reduces the incidence of sensory disturbances on the upper limb.展开更多
<strong>Introduction:</strong><span><span><span style="font-family:""><span style="font-family:Verdana;"> Cystic breast cancer is a rare entity. Breast cyst...<strong>Introduction:</strong><span><span><span style="font-family:""><span style="font-family:Verdana;"> Cystic breast cancer is a rare entity. Breast cysts are most often benign. The clinical characteristics of malignancy are not specific. </span><b><span style="font-family:Verdana;">Objective:</span></b> <span style="font-family:Verdana;">To report a series of malignant cystic tumors of the breast and to describe</span><span style="font-family:Verdana;"> their different characteristics. </span><b><span style="font-family:Verdana;">Materials and Methods:</span></b><span style="font-family:Verdana;"> This was an observational study carried out between January 2018 and October 2021 at the Dakar </span><span style="font-family:Verdana;">university surgical oncology unit. We studied the clinical appearance, im</span><span style="font-family:Verdana;">ag</span><span style="font-family:Verdana;">ing, </span><span style="font-family:Verdana;">histopathology, extent of disease and treatment. We did not include cases of</span><span style="font-family:Verdana;"> pure, single, or multiple chronically progressive cysts. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> There were 8 </span><span style="font-family:Verdana;">patients, 6 women and 2 men. The average age was 44. All patients presented </span><span style="font-family:Verdana;">with a palpable unilateral deforming skin mass without inflammatory </span><span style="font-family:Verdana;">character. One patient presented with a bloody discharge. The cyst was</span><span style="font-family:Verdana;"> multilocular with</span><span style="font-family:Verdana;">out intracystic growth in 2 cases and presented a growth signal in 6 cases.</span> <span style="font-family:Verdana;">Imaging was ACR 3 in 5 cases and ACR 4 in 3 cases. Histopathology found 6</span><span style="font-family:Verdana;"> in</span><span style="font-family:Verdana;">va</span><span style="font-family:Verdana;">sive carcinomas including 2 papillary, 3 Invasive Carcinoma of No Special</span><span style="font-family:Verdana;"> Type (ICNST), 1 lobular carcinoma as well as one case of lobular carcinoma </span><i><span style="font-family:Verdana;">in situ</span></i><span style="font-family:Verdana;"> of the comedocarcinoma type in women and 2 ICNST in men. The extension </span><span style="font-family:Verdana;">workup was found in only 1 male patient in the presence of metastases.</span><span style="font-family:Verdana;"> Treatment included chemotherapy, mastectomy and radiotherapy for 6 of </span><span style="font-family:Verdana;">the patients. There wasn’t any complete response for invasive cases. Survival is 100% to date.</span><span> <b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> Cystic breast tumors sometimes hide the cancer</span></span><span style="font-family:Verdana;"> that is difficult to diagnose. The prognosis seems favorable, however.</span></span></span></span>展开更多
文摘Background: Surgery is the treatment for early-stage cervical cancer. Radiochemotherapy is used in the treatment of locally advanced stages. But the choice of treatment can be difficult. Objective: The objective of this work was to evaluate the therapeutic aspects of cervical cancer in the early stages IA to IIA in the oncology department of A Ledantec Hospital in Dakar. Patients and methods: This was a descriptive retrospective study, from January 2015 to December 2020, in the oncology department of A Ledantec Hospital, including all the patients who had been treated for early-stage invasive cervical cancer. Results: We included 28 patients. The average age was 49.54 years old. There were 11 patients (39.3%) with a stage ≤ IB1. Surgery was the first in 14 patients (50%). The initial approach was a midline supra and subumbilical laparotomy. The surgery was R0 in 65.22%. Postoperative complications were found in 4 patients including 1 case of operative wound suppuration, 1 case of dysuria, 1 case of postoperative eventration and 1 case of rectovaginal fistula. Concomitant Radiochemotherapy was neoadjuvant in 7 cases (25%), adjuvant in 14 cases (50%). The chemotherapy was neoadjuvant in 09 cases (56.25%) and adjuvant in 7 cases (43.75%) with minor toxicities. We had recorded 2 deaths. Conclusion: The treatment of the early stages of invasive cervical cancer is based on surgery. Neoadjuvant treatments may be useful in particular situations.
文摘<strong>Introduction:</strong><span style="font-family:Verdana;"> The principal postoperative complication of mastectomies with</span><span style="font-family:Verdana;"> axillary dissection is the lymphocele that can last many months after surgery. The purpose of our study was to prevent its formation using the padding.</span><span style="font-family:""> </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> Sixty-one patients have been included in our study. The follow-up was 6 months. The patients were divided in two groups through a random draw (simple drainage and drainage associated with padding). All patients had a mastectomy with axillary dissection following the Madden technique. All quantities of lymphoceles during postoperative hospitalization and ambulatory care have been noted.</span><span style="font-family:""> </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> Twenty-five patients had benefited f</span><span style="font-family:Verdana;">rom</span><span style="font-family:Verdana;"> the padding and 36 of a simple axillary drainage. Six months after the surgery, the patients benefitting from the padding had a quantity of lymphocele equal to half that of the control group (761.83 mL against 1373.60 mL;p = 0.01). During the postoperative hospitalization, the quantities were of 362.80 mL for the padding group versus 630.83 mL;p < 0.01. The hospitalization period was shorter for the padding patients (3.72 days vs 5.14 days;p = 0.01). However, pain was greater for the padding group upon 6 months (0.26 vs 0.10;p = 0.04). On another note, padding does not influence the duration of the surgery.</span><span style="font-family:""> </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> The production of postoperative lymphocele is heterogenous, varying from one patient to another. Nevertheless, the padding of the mastectomy compartment and of the axillary cavity allow</span><span style="font-family:Verdana;">s</span><span style="font-family:Verdana;"> a noticeable reduction of the produced quantity and of the hospitalization period at the expense of more pain.</span>
文摘The intercostobrachial nerve (ICBN) is responsible for the sensory</span></span></span></span></span><span><span><span><span><span><span style="font-family:""><span style="font-family:Verdana;"> innervation of a part of the inner side of the arm. Injury of the intercostobrachial nerve is </span><span style="font-family:Verdana;">a complication of axillary dissection during lymph node dissection.</span> <b><span style="font-family:Verdana;">Objective</span></b><span style="font-family:Verdana;">: </span><span style="font-family:Verdana;">This study aimed to determine the effect of preservation of the</span><span style="font-family:Verdana;"> intercostobra</span><span><span style="font-family:Verdana;">chial nerve on postoperative sensory disturbances. </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> This is a</span></span><span style="font-family:Verdana;"> prospective, single-center study which was carried out in 90 patients followed in the oncology department of the Aristide Le Dantec hospital in Dakar, suffering </span><span style="font-family:Verdana;">from breast cancer and having undergone breast surgery associated with</span><span style="font-family:Verdana;"> axillary </span><span style="font-family:Verdana;">dissection, for a period of 6 months. The patients were divided into two</span><span style="font-family:Verdana;"> groups depending on whether the intercostobrachial nerve (ICBN) was preserved or </span><span style="font-family:Verdana;">not. The two groups were compared in terms of the incidence of sensory</span><span style="font-family:Verdana;"> disturbances. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> Sixty patients without nerve preservation and 30 patients with nerve preservation were included in the study, </span><i><span style="font-family:Verdana;">i.e.</span></i><span style="font-family:Verdana;">, 90 patients in total. </span><span style="font-family:Verdana;">ICBN was injured in 60 patients of which 41 patients (83.7%) developed</span><span style="font-family:Verdana;"> numbness in the inner arm. While in the preserved group, only 8 patients suffered from numbness (16.3%) with a significant P value of 0.002;however, for </span><span style="font-family:Verdana;">other </span><span style="font-family:Verdana;">variables such as the incidence of neuropathic pain and hypoesthesia-like</span><span style="font-family:Verdana;"> sensory </span><span><span style="font-family:Verdana;">deficit, there was no significant difference. </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> Preservation of the </span></span><span style="font-family:Verdana;">intercostobrachial nerve during axillary dissection for breast cancer reduces the incidence of sensory disturbances on the upper limb.
文摘<strong>Introduction:</strong><span><span><span style="font-family:""><span style="font-family:Verdana;"> Cystic breast cancer is a rare entity. Breast cysts are most often benign. The clinical characteristics of malignancy are not specific. </span><b><span style="font-family:Verdana;">Objective:</span></b> <span style="font-family:Verdana;">To report a series of malignant cystic tumors of the breast and to describe</span><span style="font-family:Verdana;"> their different characteristics. </span><b><span style="font-family:Verdana;">Materials and Methods:</span></b><span style="font-family:Verdana;"> This was an observational study carried out between January 2018 and October 2021 at the Dakar </span><span style="font-family:Verdana;">university surgical oncology unit. We studied the clinical appearance, im</span><span style="font-family:Verdana;">ag</span><span style="font-family:Verdana;">ing, </span><span style="font-family:Verdana;">histopathology, extent of disease and treatment. We did not include cases of</span><span style="font-family:Verdana;"> pure, single, or multiple chronically progressive cysts. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> There were 8 </span><span style="font-family:Verdana;">patients, 6 women and 2 men. The average age was 44. All patients presented </span><span style="font-family:Verdana;">with a palpable unilateral deforming skin mass without inflammatory </span><span style="font-family:Verdana;">character. One patient presented with a bloody discharge. The cyst was</span><span style="font-family:Verdana;"> multilocular with</span><span style="font-family:Verdana;">out intracystic growth in 2 cases and presented a growth signal in 6 cases.</span> <span style="font-family:Verdana;">Imaging was ACR 3 in 5 cases and ACR 4 in 3 cases. Histopathology found 6</span><span style="font-family:Verdana;"> in</span><span style="font-family:Verdana;">va</span><span style="font-family:Verdana;">sive carcinomas including 2 papillary, 3 Invasive Carcinoma of No Special</span><span style="font-family:Verdana;"> Type (ICNST), 1 lobular carcinoma as well as one case of lobular carcinoma </span><i><span style="font-family:Verdana;">in situ</span></i><span style="font-family:Verdana;"> of the comedocarcinoma type in women and 2 ICNST in men. The extension </span><span style="font-family:Verdana;">workup was found in only 1 male patient in the presence of metastases.</span><span style="font-family:Verdana;"> Treatment included chemotherapy, mastectomy and radiotherapy for 6 of </span><span style="font-family:Verdana;">the patients. There wasn’t any complete response for invasive cases. Survival is 100% to date.</span><span> <b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> Cystic breast tumors sometimes hide the cancer</span></span><span style="font-family:Verdana;"> that is difficult to diagnose. The prognosis seems favorable, however.</span></span></span></span>