期刊文献+
共找到1篇文章
< 1 >
每页显示 20 50 100
Gut Microbiota in Metabolic-associated Fatty Liver Disease and in Other Chronic Metabolic Diseases 被引量:8
1
作者 Winston Hernández-Ceballos jacqueline cordova-gallardo Nahum Mendez-Sanchez 《Journal of Clinical and Translational Hepatology》 SCIE 2021年第2期227-238,共12页
The gut microbiome plays a key role in the health-disease balance in the human body.Although its composition is unique for each person and tends to remain stable throughout lifetime,it has been shown that certain bact... The gut microbiome plays a key role in the health-disease balance in the human body.Although its composition is unique for each person and tends to remain stable throughout lifetime,it has been shown that certain bacterial patterns may be determining factors in the onset of certain chronic metabolic diseases,such as type 2 diabetes mellitus(T2DM),obesity,metabolic-associated fatty liver disease(MAFLD),and metabolic syndrome.The gut-liver axis embodies the close relationship between the gut and the liver;disturbance of the normal gut microbiota,also known as dysbiosis,may lead to a cascade of mechanisms that modify the epithelial properties and facilitate bacterial translocation.Regulation of gut microbiota is fundamental to maintaining gut integrity,as well as the bile acids composition.In the present review,we summarize the current knowledge regarding the microbiota,bile acids composition and their association with MAFLD,obesity,T2DM and metabolic syndrome. 展开更多
关键词 Metabolic-associated fatty liver disease Metabolic-associated steatohepatitis Gut microbiota Gut-liver axis DYSBIOSIS Bile acids
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部