Exploitation of green chemistry approach for the synthesis of Indium Oxide nanoparticles using green synthesis has received a great attention in the field of nanotechnology. To demonstrate a biogenic method that invol...Exploitation of green chemistry approach for the synthesis of Indium Oxide nanoparticles using green synthesis has received a great attention in the field of nanotechnology. To demonstrate a biogenic method that involves the Katira gum (Astragalus gummifer) leading to the formation of different morphological In<sub>2</sub>O<sub>3</sub> using the precursor Indium (III) Acetylacetonate and TG-DTA is characterised for calcination temperature and it is found to be above 500℃. Different techniques such as XRD, UV-VIS, SEM and EDAX have been used for the characterisation of In<sub>2</sub>O<sub>3</sub> nanoparticles. The average crystallite size of Indiumoxide nanoparticles is determined as 19 nm by using Scherrer’s Equation and PSA and studying optical properties.展开更多
10-（4-Formylphenyl）-5,15-bis（pentafluorophenyl）corrole 1 and its gallium complex 1-Ga were used to investigate their photocytotoxicity in liver cancer （BEL-7402）, lung cancer （A549） and cervical cancer （Siha,...10-（4-Formylphenyl）-5,15-bis（pentafluorophenyl）corrole 1 and its gallium complex 1-Ga were used to investigate their photocytotoxicity in liver cancer （BEL-7402）, lung cancer （A549） and cervical cancer （Siha, Hela） cell lines. Among all the tested tumor cells, Siha tumor cells were the most sensitive to photodynamic therapy （PDT） treatment by 1 and 1-Ga. PDT IC50 of 1 and 1-Ga toward Siha tumor cell reaches 1.3 and 0.8 gmol/L respectively, which is 10-fold higher than that of cisplatin. 1 and 1-Ga might pass across the tumor cell membrane smoothly without the help of carrier protein, and mainly localized in the cytoplasm of tumor cell. After PDT treatment, the intracellular reactive oxygen species （ROS） level increased and the mitochondrial membrane potential decreased significantly, which would finally result in the apoptosis of tumor cells.展开更多
A new 2-chloro-5,10,15-tris（2,4,6-triphenylphenyl）-corrole was accidentally synthesized in an acceptable yield of 5.7% during the synthesis of its parent corrole, in which DDQ served as oxidant and chlorinating agen...A new 2-chloro-5,10,15-tris（2,4,6-triphenylphenyl）-corrole was accidentally synthesized in an acceptable yield of 5.7% during the synthesis of its parent corrole, in which DDQ served as oxidant and chlorinating agent. The compound was well characterized by X-ray diffraction analysis,;H NMR, mass spectroscopy and absorption spectroscopy. Photophysical properties tests revealed that the chlorination caused a sharp decrease in fluorescence intensity, fluorescence life time, and fluorescence quantum yield.Electrochemical investigation demonstrated the positive shift of redox potentials for chlorinated corrole as compared to non-chlorinated corrole.展开更多
文摘Exploitation of green chemistry approach for the synthesis of Indium Oxide nanoparticles using green synthesis has received a great attention in the field of nanotechnology. To demonstrate a biogenic method that involves the Katira gum (Astragalus gummifer) leading to the formation of different morphological In<sub>2</sub>O<sub>3</sub> using the precursor Indium (III) Acetylacetonate and TG-DTA is characterised for calcination temperature and it is found to be above 500℃. Different techniques such as XRD, UV-VIS, SEM and EDAX have been used for the characterisation of In<sub>2</sub>O<sub>3</sub> nanoparticles. The average crystallite size of Indiumoxide nanoparticles is determined as 19 nm by using Scherrer’s Equation and PSA and studying optical properties.
基金This work was supported by National Natural Sci-ence Foundation of China （NNSFC） under Grant （Nos., 21371059, 21671068）, the National Science Foundation of Guangdong Province （No. 2016A030313728）, the Open Fund of State Key Laboratory of Optoelectronic Materials and Technologies （Sun Yat-sen University） （No. OEMT-2015-KF-05）.
文摘10-（4-Formylphenyl）-5,15-bis（pentafluorophenyl）corrole 1 and its gallium complex 1-Ga were used to investigate their photocytotoxicity in liver cancer （BEL-7402）, lung cancer （A549） and cervical cancer （Siha, Hela） cell lines. Among all the tested tumor cells, Siha tumor cells were the most sensitive to photodynamic therapy （PDT） treatment by 1 and 1-Ga. PDT IC50 of 1 and 1-Ga toward Siha tumor cell reaches 1.3 and 0.8 gmol/L respectively, which is 10-fold higher than that of cisplatin. 1 and 1-Ga might pass across the tumor cell membrane smoothly without the help of carrier protein, and mainly localized in the cytoplasm of tumor cell. After PDT treatment, the intracellular reactive oxygen species （ROS） level increased and the mitochondrial membrane potential decreased significantly, which would finally result in the apoptosis of tumor cells.
基金financially supported by the National Natural Science Foundation of China(Nos.21671068,81400023,61178037,81273549)National Basic Research Program(973 Program)of China(No.2013CB922403)the Open Fund of State Key Laboratory of Optoelectronic Materials and Technologies,Sun Yatsen University(No.OEMT-2015-KF-05)
文摘A new 2-chloro-5,10,15-tris（2,4,6-triphenylphenyl）-corrole was accidentally synthesized in an acceptable yield of 5.7% during the synthesis of its parent corrole, in which DDQ served as oxidant and chlorinating agent. The compound was well characterized by X-ray diffraction analysis,;H NMR, mass spectroscopy and absorption spectroscopy. Photophysical properties tests revealed that the chlorination caused a sharp decrease in fluorescence intensity, fluorescence life time, and fluorescence quantum yield.Electrochemical investigation demonstrated the positive shift of redox potentials for chlorinated corrole as compared to non-chlorinated corrole.
